GALNT11 (polypeptide N-acetylgalactosaminyltransferase 11)

2014-11-01  

Identity

HGNC
GALNT11
LOCATION
7q36.1
LOCUSID
63917
ALIAS
GALNAC-T11,GALNACT11
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 63917
MIM: 615130
HGNC: 19875
Ensembl: ENSG00000178234

Variants:

dbSNP: 63917
ClinVar: 63917
TCGA: ENSG00000178234
COSMIC: GALNT11

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000178234ENST00000415421Q8NCW6
ENSG00000178234ENST00000419245C9J8A7
ENSG00000178234ENST00000422997Q8NCW6
ENSG00000178234ENST00000423337C9K0N9
ENSG00000178234ENST00000430044Q8NCW6
ENSG00000178234ENST00000430044A0A090N7X6
ENSG00000178234ENST00000431668C9JMT8
ENSG00000178234ENST00000431940H7BZL5
ENSG00000178234ENST00000434507Q8NCW6
ENSG00000178234ENST00000434507A0A090N7X6
ENSG00000178234ENST00000446096C9JPR8
ENSG00000178234ENST00000447778B7Z3L9
ENSG00000178234ENST00000447796C9J111

Expression (GTEx)

0
5
10
15
20
25
30
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Mucin type O-glycan biosynthesisKEGGko00512
Mucin type O-glycan biosynthesisKEGGhsa00512
Metabolic pathwaysKEGGhsa01100
O-glycan biosynthesis, mucin type coreKEGGhsa_M00056
O-glycan biosynthesis, mucin type coreKEGGM00056
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
O-linked glycosylationREACTOMER-HSA-5173105
O-linked glycosylation of mucinsREACTOMER-HSA-913709

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
254939552015Genome-wide association study of kidney function decline in individuals of European descent.36
204224472010Rescue of Drosophila Melanogaster l(2)35Aa lethality is only mediated by polypeptide GalNAc-transferase pgant35A, but not by the evolutionary conserved human ortholog GalNAc-transferase-T11.8
240763512014GALNT11 as a new molecular marker in chronic lymphocytic leukemia.7
205470882010A Japanese-specific allele in the GALNT11 gene.0
205470882010A Japanese-specific allele in the GALNT11 gene.0

Citation

Dessen P

GALNT11 (polypeptide N-acetylgalactosaminyltransferase 11)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/63683/galnt11