Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2587
MIM: 600377
HGNC: 4132
Ensembl: ENSG00000166573
Variants:
dbSNP: 2587
ClinVar: 2587
TCGA: ENSG00000166573
COSMIC: GALR1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000166573 | ENST00000299727 | P47211 |
Expression (GTEx)
Pathways
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA445876 | Tobacco Use Disorder | Disease | ClinicalAnnotation | associated | PD | 21430647, 22373943 | |
| PA448687 | bupropion | Chemical | ClinicalAnnotation | associated | PD | ||
| PA450626 | nicotine | Chemical | ClinicalAnnotation | associated | PD | 21430647, 22373943 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35409094 | 2022 | Galanin Receptors (GalR1, GalR2, and GalR3) Expression in Colorectal Cancer Tissue and Correlations to the Overall Survival and Poor Prognosis of CRC Patients. | 6 |
| 35606503 | 2022 | Promoter hypermethylation of GALR1 acts as an early epigenetic susceptibility event in colorectal carcinogenesis. | 2 |
| 35409094 | 2022 | Galanin Receptors (GalR1, GalR2, and GalR3) Expression in Colorectal Cancer Tissue and Correlations to the Overall Survival and Poor Prognosis of CRC Patients. | 6 |
| 35606503 | 2022 | Promoter hypermethylation of GALR1 acts as an early epigenetic susceptibility event in colorectal carcinogenesis. | 2 |
| 32757697 | 2020 | Further evidence for the association of GAL, GALR1 and NPY1R variants with opioid dependence. | 1 |
| 33150179 | 2020 | A Three Protein-Coding Gene Prognostic Model Predicts Overall Survival in Bladder Cancer Patients. | 5 |
| 32757697 | 2020 | Further evidence for the association of GAL, GALR1 and NPY1R variants with opioid dependence. | 1 |
| 33150179 | 2020 | A Three Protein-Coding Gene Prognostic Model Predicts Overall Survival in Bladder Cancer Patients. | 5 |
| 30616468 | 2019 | Galanin expression is down-regulated in patients with gastric cancer. | 8 |
| 30616468 | 2019 | Galanin expression is down-regulated in patients with gastric cancer. | 8 |
| 27685843 | 2017 | Site-specific methylation patterns of the GAL and GALR1/2 genes in head and neck cancer: Potential utility as biomarkers for prognosis. | 19 |
| 28007761 | 2017 | Functional μ-Opioid-Galanin Receptor Heteromers in the Ventral Tegmental Area. | 16 |
| 27685843 | 2017 | Site-specific methylation patterns of the GAL and GALR1/2 genes in head and neck cancer: Potential utility as biomarkers for prognosis. | 19 |
| 28007761 | 2017 | Functional μ-Opioid-Galanin Receptor Heteromers in the Ventral Tegmental Area. | 16 |
| 26572146 | 2016 | Epigenetic inactivation of galanin and GALR1/2 is associated with early recurrence in head and neck cancer. | 15 |
Citation
Dessen P
GALR1 (galanin receptor 1)
Atlas Genet Cytogenet Oncol Haematol. 2009-03-01
Online version: http://atlasgeneticsoncology.org/gene/50690/galr1
