Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

GAMT (guanidinoacetate N-methyltransferase)

Identity

Alias (NCBI)CCDS2
HEL-S-20
PIG2
TP53I2
HGNC (Hugo) GAMT
HGNC Alias symbPIG2
TP53I2
LocusID (NCBI) 2593
Atlas_Id 63694
Location 19p13.3  [Link to chromosome band 19p13]
Location_base_pair Starts at 1397815 and ends at 1401542 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)GAMT   4136
Cards
Entrez_Gene (NCBI)GAMT    guanidinoacetate N-methyltransferase
AliasesCCDS2; HEL-S-20; PIG2; TP53I2
GeneCards (Weizmann)GAMT
Ensembl hg19 (Hinxton)ENSG00000130005 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000130005 [Gene_View]  ENSG00000130005 [Sequence]  chr19:1397815-1401542 [Contig_View]  GAMT [Vega]
ICGC DataPortalENSG00000130005
TCGA cBioPortalGAMT
AceView (NCBI)GAMT
Genatlas (Paris)GAMT
SOURCE (Princeton)GAMT
Genetics Home Reference (NIH)GAMT
Genomic and cartography
GoldenPath hg38 (UCSC)GAMT  -     chr19:1397815-1401542 -  19p13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GAMT  -     19p13.3   [Description]    (hg19-Feb_2009)
GoldenPathGAMT - 19p13.3 [CytoView hg19]  GAMT - 19p13.3 [CytoView hg38]
ImmunoBaseENSG00000130005
Genome Data Viewer NCBIGAMT [Mapview hg19]  
OMIM601240   612736   
Gene and transcription
Genbank (Entrez)AF086508 AK289465 AK297487 BC016760 BC017936
RefSeq transcript (Entrez)NM_000156 NM_138924
Consensus coding sequences : CCDS (NCBI)GAMT
Gene ExpressionGAMT [ NCBI-GEO ]   GAMT [ EBI - ARRAY_EXPRESS ]   GAMT [ SEEK ]   GAMT [ MEM ]
Gene Expression Viewer (FireBrowse)GAMT [ Firebrowse - Broad ]
GenevisibleExpression of GAMT in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2593
GTEX Portal (Tissue expression)GAMT
Human Protein AtlasENSG00000130005-GAMT [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ14353   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ14353  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ14353
PhosPhoSitePlusQ14353
Domaine pattern : Prosite (Expaxy)SAM_RMT2 (PS51559)   
Domains : Interpro (EBI)GuanidinoAc_N-MeTrfase    RMT2_dom    SAM-dependent_MTases   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)GAMT
PDB (RSDB)3ORH   
PDB Europe3ORH   
PDB (PDBSum)3ORH   
PDB (IMB)3ORH   
Structural Biology KnowledgeBase3ORH   
SCOP (Structural Classification of Proteins)3ORH   
CATH (Classification of proteins structures)3ORH   
SuperfamilyQ14353
AlphaFold pdb e-kbQ14353   
Human Protein Atlas [tissue]ENSG00000130005-GAMT [tissue]
HPRD03142
Protein Interaction databases
DIP (DOE-UCLA)Q14353
IntAct (EBI)Q14353
BioGRIDGAMT
STRING (EMBL)GAMT
ZODIACGAMT
Ontologies - Pathways
QuickGOQ14353
Ontology : AmiGOprotein binding  nucleus  cytoplasm  cytosol  creatine metabolic process  creatine biosynthetic process  creatine biosynthetic process  creatine biosynthetic process  muscle contraction  spermatogenesis  methyltransferase activity  S-adenosylmethionine-dependent methyltransferase activity  animal organ morphogenesis  guanidinoacetate N-methyltransferase activity  guanidinoacetate N-methyltransferase activity  methylation  regulation of multicellular organism growth  
Ontology : EGO-EBIprotein binding  nucleus  cytoplasm  cytosol  creatine metabolic process  creatine biosynthetic process  creatine biosynthetic process  creatine biosynthetic process  muscle contraction  spermatogenesis  methyltransferase activity  S-adenosylmethionine-dependent methyltransferase activity  animal organ morphogenesis  guanidinoacetate N-methyltransferase activity  guanidinoacetate N-methyltransferase activity  methylation  regulation of multicellular organism growth  
Pathways : KEGGGlycine, serine and threonine metabolism    Urea cycle and metabolism of amino groups    Arginine and proline metabolism   
NDEx NetworkGAMT
Atlas of Cancer Signalling NetworkGAMT
Wikipedia pathwaysGAMT
Orthology - Evolution
OrthoDB2593
GeneTree (enSembl)ENSG00000130005
Phylogenetic Trees/Animal Genes : TreeFamGAMT
Homologs : HomoloGeneGAMT
Homology/Alignments : Family Browser (UCSC)GAMT
Gene fusions - Rearrangements
Fusion : QuiverGAMT
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGAMT [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GAMT
dbVarGAMT
ClinVarGAMT
MonarchGAMT
1000_GenomesGAMT 
Exome Variant ServerGAMT
GNOMAD BrowserENSG00000130005
Varsome BrowserGAMT
ACMGGAMT variants
VarityQ14353
Genomic Variants (DGV)GAMT [DGVbeta]
DECIPHERGAMT [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGAMT 
Mutations
ICGC Data PortalGAMT 
TCGA Data PortalGAMT 
Broad Tumor PortalGAMT
OASIS PortalGAMT [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGAMT  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DGAMT
Mutations and Diseases : HGMDGAMT
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaGAMT
DgiDB (Drug Gene Interaction Database)GAMT
DoCM (Curated mutations)GAMT
CIViC (Clinical Interpretations of Variants in Cancer)GAMT
Cancer3DGAMT
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601240    612736   
Orphanet1726   
DisGeNETGAMT
MedgenGAMT
Genetic Testing Registry GAMT
NextProtQ14353 [Medical]
GENETestsGAMT
Target ValidationGAMT
Huge Navigator GAMT [HugePedia]
ClinGenGAMT
Clinical trials, drugs, therapy
MyCancerGenomeGAMT
Protein Interactions : CTDGAMT
Pharm GKB GenePA28549
PharosQ14353
Clinical trialGAMT
Miscellaneous
canSAR (ICR)GAMT
HarmonizomeGAMT
DataMed IndexGAMT
Probes
Litterature
PubMed38 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXGAMT
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Oct 4 15:51:10 CEST 2021

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.