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GAN (gigaxonin)

Identity

Other aliasGAN1
KLHL16
HGNC (Hugo) GAN
LocusID (NCBI) 8139
Atlas_Id 57035
Location 16q23.2  [Link to chromosome band 16q23]
Location_base_pair Starts at 81314966 and ends at 81380198 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
GAN (16q23.2) / GRM7 (3p26.1)MIR100HG (11q24.1) / GAN (16q23.2)RRP1 (21q22.3) / GAN (16q23.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GAN   4137
Cards
Entrez_Gene (NCBI)GAN  8139  gigaxonin
AliasesGAN1; KLHL16
GeneCards (Weizmann)GAN
Ensembl hg19 (Hinxton) [Gene_View]
Ensembl hg38 (Hinxton) [Gene_View]  chr16:81314966-81380198 [Contig_View]  GAN [Vega]
TCGA cBioPortalGAN
AceView (NCBI)GAN
Genatlas (Paris)GAN
WikiGenes8139
SOURCE (Princeton)GAN
Genetics Home Reference (NIH)GAN
Genomic and cartography
GoldenPath hg38 (UCSC)GAN  -     chr16:81314966-81380198 +  16q23.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GAN  -     16q23.2   [Description]    (hg19-Feb_2009)
EnsemblGAN - 16q23.2 [CytoView hg19]  GAN - 16q23.2 [CytoView hg38]
Mapping of homologs : NCBIGAN [Mapview hg19]  GAN [Mapview hg38]
OMIM256850   605379   
Gene and transcription
Genbank (Entrez)AF291673 AK095378 BC016717 BC044840 HQ257897
RefSeq transcript (Entrez)NM_022041
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GAN
Cluster EST : UnigeneHs.112569 [ NCBI ]
CGAP (NCI)Hs.112569
Gene ExpressionGAN [ NCBI-GEO ]   GAN [ EBI - ARRAY_EXPRESS ]   GAN [ SEEK ]   GAN [ MEM ]
Gene Expression Viewer (FireBrowse)GAN [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8139
GTEX Portal (Tissue expression)GAN
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H2C0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H2C0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H2C0
Splice isoforms : SwissVarQ9H2C0
PhosPhoSitePlusQ9H2C0
Domaine pattern : Prosite (Expaxy)BTB (PS50097)   
Domains : Interpro (EBI)BACK    BTB-kelch_protein    BTB/POZ_dom    Kelch-typ_b-propeller    Kelch_1    KLHL16    SKP1/BTB/POZ   
Domain families : Pfam (Sanger)BACK (PF07707)    BTB (PF00651)    Kelch_1 (PF01344)   
Domain families : Pfam (NCBI)pfam07707    pfam00651    pfam01344   
Domain families : Smart (EMBL)BACK (SM00875)  BTB (SM00225)  Kelch (SM00612)  
Conserved Domain (NCBI)GAN
DMDM Disease mutations8139
Blocks (Seattle)GAN
PDB (SRS)2PPI    3HVE   
PDB (PDBSum)2PPI    3HVE   
PDB (IMB)2PPI    3HVE   
PDB (RSDB)2PPI    3HVE   
Structural Biology KnowledgeBase2PPI    3HVE   
SCOP (Structural Classification of Proteins)2PPI    3HVE   
CATH (Classification of proteins structures)2PPI    3HVE   
SuperfamilyQ9H2C0
Peptide AtlasQ9H2C0
IPIIPI00022758   
Protein Interaction databases
DIP (DOE-UCLA)Q9H2C0
IntAct (EBI)Q9H2C0
BioGRIDGAN
STRING (EMBL)GAN
ZODIACGAN
Ontologies - Pathways
QuickGOQ9H2C0
Ontology : AmiGOmolecular_function  ubiquitin-protein transferase activity  protein binding  cytoplasm  cytosol  cytoskeleton  cytoskeleton organization  protein ubiquitination  protein ubiquitination  Cul3-RING ubiquitin ligase complex  post-translational protein modification  
Ontology : EGO-EBImolecular_function  ubiquitin-protein transferase activity  protein binding  cytoplasm  cytosol  cytoskeleton  cytoskeleton organization  protein ubiquitination  protein ubiquitination  Cul3-RING ubiquitin ligase complex  post-translational protein modification  
NDEx NetworkGAN
Atlas of Cancer Signalling NetworkGAN
Wikipedia pathwaysGAN
Orthology - Evolution
OrthoDB8139
Phylogenetic Trees/Animal Genes : TreeFamGAN
HOVERGENQ9H2C0
HOGENOMQ9H2C0
Homologs : HomoloGeneGAN
Homology/Alignments : Family Browser (UCSC)GAN
Gene fusions - Rearrangements
Fusion: Tumor Portal GAN
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGAN [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GAN
dbVarGAN
ClinVarGAN
1000_GenomesGAN 
Exome Variant ServerGAN
ExAC (Exome Aggregation Consortium)
Genetic variants : HAPMAP8139
Genomic Variants (DGV)GAN [DGVbeta]
DECIPHERGAN [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGAN 
Mutations
ICGC Data PortalGAN 
TCGA Data PortalGAN 
Broad Tumor PortalGAN
OASIS PortalGAN [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGAN  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGAN
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GAN
DgiDB (Drug Gene Interaction Database)GAN
DoCM (Curated mutations)GAN (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GAN (select a term)
intoGenGAN
Cancer3DGAN(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM256850    605379   
Orphanet
MedgenGAN
Genetic Testing Registry GAN
NextProtQ9H2C0 [Medical]
TSGene8139
GENETestsGAN
Target ValidationGAN
Huge Navigator GAN [HugePedia]
snp3D : Map Gene to Disease8139
BioCentury BCIQGAN
ClinGenGAN
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD8139
Chemical/Pharm GKB GenePA28550
Clinical trialGAN
Miscellaneous
canSAR (ICR)GAN (select the gene name)
Probes
Litterature
PubMed39 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGAN
EVEXGAN
GoPubMedGAN
iHOPGAN
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Nov 9 12:50:55 CET 2017

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