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GANAB (glucosidase II alpha subunit)

Identity

Alias_namesglucosidase
Alias_symbol (synonym)GluII
G2AN
KIAA0088
GIIA
Other aliasGLUII
PKD3
HGNC (Hugo) GANAB
LocusID (NCBI) 23193
Atlas_Id 52541
Location 11q12.3  [Link to chromosome band 11q12]
Location_base_pair Starts at 62624826 and ends at 62646726 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ASNA1 (19p13.2) / GANAB (11q12.3)B3GAT3 (11q12.3) / GANAB (11q12.3)GANAB (11q12.3) / GANAB (11q12.3)
GANAB (11q12.3) / STX7 (6q23.2)GANAB (11q12.3) / STXBP5L (3q13.33)GRM8 (7q31.33) / GANAB (11q12.3)
PRKCSH (19p13.2) / GANAB (11q12.3)RAMP1 (2q37.3) / GANAB (11q12.3)RPL18 (19q13.33) / GANAB (11q12.3)
RPS6 (9p22.1) / GANAB (11q12.3)TRAF6 (11p12) / GANAB (11q12.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GANAB   4138
Cards
Entrez_Gene (NCBI)GANAB  23193  glucosidase II alpha subunit
AliasesG2AN; GIIA; GLUII; PKD3
GeneCards (Weizmann)GANAB
Ensembl hg19 (Hinxton)ENSG00000089597 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000089597 [Gene_View]  chr11:62624826-62646726 [Contig_View]  GANAB [Vega]
ICGC DataPortalENSG00000089597
TCGA cBioPortalGANAB
AceView (NCBI)GANAB
Genatlas (Paris)GANAB
WikiGenes23193
SOURCE (Princeton)GANAB
Genetics Home Reference (NIH)GANAB
Genomic and cartography
GoldenPath hg38 (UCSC)GANAB  -     chr11:62624826-62646726 -  11q12.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GANAB  -     11q12.3   [Description]    (hg19-Feb_2009)
EnsemblGANAB - 11q12.3 [CytoView hg19]  GANAB - 11q12.3 [CytoView hg38]
Mapping of homologs : NCBIGANAB [Mapview hg19]  GANAB [Mapview hg38]
OMIM104160   600666   
Gene and transcription
Genbank (Entrez)AA618561 AF144074 AJ000332 AK026548 AK026567
RefSeq transcript (Entrez)NM_001278192 NM_001278193 NM_001278194 NM_001329222 NM_001329223 NM_001329224 NM_001329225 NM_014610 NM_198334 NM_198335
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GANAB
Cluster EST : UnigeneHs.595071 [ NCBI ]
CGAP (NCI)Hs.595071
Alternative Splicing GalleryENSG00000089597
Gene ExpressionGANAB [ NCBI-GEO ]   GANAB [ EBI - ARRAY_EXPRESS ]   GANAB [ SEEK ]   GANAB [ MEM ]
Gene Expression Viewer (FireBrowse)GANAB [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23193
GTEX Portal (Tissue expression)GANAB
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ14697   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ14697  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ14697
Splice isoforms : SwissVarQ14697
Catalytic activity : Enzyme3.2.1.84 [ Enzyme-Expasy ]   3.2.1.843.2.1.84 [ IntEnz-EBI ]   3.2.1.84 [ BRENDA ]   3.2.1.84 [ KEGG ]   
PhosPhoSitePlusQ14697
Domaine pattern : Prosite (Expaxy)GLYCOSYL_HYDROL_F31_1 (PS00129)    GLYCOSYL_HYDROL_F31_2 (PS00707)   
Domains : Interpro (EBI)Gal_mutarotase_SF_dom    Glyco_hydro_31    Glyco_hydro_31_AS    Glyco_hydro_31_CS    Glyco_hydro_31_N_dom    Glycoside_hydrolase_SF   
Domain families : Pfam (Sanger)Gal_mutarotas_2 (PF13802)    Glyco_hydro_31 (PF01055)   
Domain families : Pfam (NCBI)pfam13802    pfam01055   
Conserved Domain (NCBI)GANAB
DMDM Disease mutations23193
Blocks (Seattle)GANAB
SuperfamilyQ14697
Human Protein AtlasENSG00000089597
Peptide AtlasQ14697
HPRD03516
IPIIPI00011454   IPI00441414   IPI00383581   IPI01012526   IPI00747078   IPI00983378   IPI00977245   IPI00984677   IPI00977946   IPI01012142   
Protein Interaction databases
DIP (DOE-UCLA)Q14697
IntAct (EBI)Q14697
FunCoupENSG00000089597
BioGRIDGANAB
STRING (EMBL)GANAB
ZODIACGANAB
Ontologies - Pathways
QuickGOQ14697
Ontology : AmiGORNA binding  endoplasmic reticulum lumen  Golgi apparatus  carbohydrate metabolic process  protein folding  membrane  glucosidase II complex  carbohydrate binding  extracellular matrix  glucan 1,3-alpha-glucosidase activity  melanosome  extracellular exosome  
Ontology : EGO-EBIRNA binding  endoplasmic reticulum lumen  Golgi apparatus  carbohydrate metabolic process  protein folding  membrane  glucosidase II complex  carbohydrate binding  extracellular matrix  glucan 1,3-alpha-glucosidase activity  melanosome  extracellular exosome  
Pathways : BIOCARTAER?associated degradation (ERAD) Pathway [Genes]   
Pathways : KEGGN-Glycan biosynthesis    Protein processing in endoplasmic reticulum   
NDEx NetworkGANAB
Atlas of Cancer Signalling NetworkGANAB
Wikipedia pathwaysGANAB
Orthology - Evolution
OrthoDB23193
GeneTree (enSembl)ENSG00000089597
Phylogenetic Trees/Animal Genes : TreeFamGANAB
HOVERGENQ14697
HOGENOMQ14697
Homologs : HomoloGeneGANAB
Homology/Alignments : Family Browser (UCSC)GANAB
Gene fusions - Rearrangements
Fusion Cancer (Beijing)B3GAT3 [11q12.3]  -  GANAB [11q12.3]  [FUSC001248]  [FUSC001248]  [FUSC001248]
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGANAB [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GANAB
dbVarGANAB
ClinVarGANAB
1000_GenomesGANAB 
Exome Variant ServerGANAB
ExAC (Exome Aggregation Consortium)GANAB (select the gene name)
Genetic variants : HAPMAP23193
Genomic Variants (DGV)GANAB [DGVbeta]
DECIPHERGANAB [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGANAB 
Mutations
ICGC Data PortalGANAB 
TCGA Data PortalGANAB 
Broad Tumor PortalGANAB
OASIS PortalGANAB [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGANAB  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGANAB
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GANAB
DgiDB (Drug Gene Interaction Database)GANAB
DoCM (Curated mutations)GANAB (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GANAB (select a term)
intoGenGANAB
Cancer3DGANAB(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM104160    600666   
Orphanet
MedgenGANAB
Genetic Testing Registry GANAB
NextProtQ14697 [Medical]
TSGene23193
GENETestsGANAB
Target ValidationGANAB
Huge Navigator GANAB [HugePedia]
snp3D : Map Gene to Disease23193
BioCentury BCIQGANAB
ClinGenGANAB
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD23193
Chemical/Pharm GKB GenePA28551
Clinical trialGANAB
Miscellaneous
canSAR (ICR)GANAB (select the gene name)
Probes
Litterature
PubMed94 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGANAB
EVEXGANAB
GoPubMedGANAB
iHOPGANAB
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 12:34:51 CEST 2017

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