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GAREM2 (GRB2 associated regulator of MAPK1 subtype 2)

Identity

Alias_namesFAM59B
GAREML
family with sequence similarity 59, member B
GRB2 associated, regulator of MAPK1-like
Alias_symbol (synonym)KIAA2038
FLJ00375
Other alias
HGNC (Hugo) GAREM2
LocusID (NCBI) 150946
Atlas_Id 77834
Location 2p23.3  [Link to chromosome band 2p23]
Location_base_pair Starts at 26173091 and ends at 26189663 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GAREM2   27172
Cards
Entrez_Gene (NCBI)GAREM2  150946  GRB2 associated regulator of MAPK1 subtype 2
AliasesFAM59B; GAREML
GeneCards (Weizmann)GAREM2
Ensembl hg19 (Hinxton)ENSG00000157833 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000157833 [Gene_View]  chr2:26173091-26189663 [Contig_View]  GAREM2 [Vega]
ICGC DataPortalENSG00000157833
TCGA cBioPortalGAREM2
AceView (NCBI)GAREM2
Genatlas (Paris)GAREM2
WikiGenes150946
SOURCE (Princeton)GAREM2
Genetics Home Reference (NIH)GAREM2
Genomic and cartography
GoldenPath hg38 (UCSC)GAREM2  -     chr2:26173091-26189663 +  2p23.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GAREM2  -     2p23.3   [Description]    (hg19-Feb_2009)
EnsemblGAREM2 - 2p23.3 [CytoView hg19]  GAREM2 - 2p23.3 [CytoView hg38]
Mapping of homologs : NCBIGAREM2 [Mapview hg19]  GAREM2 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AA736392 AB015349 AB124552 AK090454 CX759737
RefSeq transcript (Entrez)NM_001168241 NM_001191033
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GAREM2
Cluster EST : UnigeneHs.187912 [ NCBI ]
CGAP (NCI)Hs.187912
Alternative Splicing GalleryENSG00000157833
Gene ExpressionGAREM2 [ NCBI-GEO ]   GAREM2 [ EBI - ARRAY_EXPRESS ]   GAREM2 [ SEEK ]   GAREM2 [ MEM ]
Gene Expression Viewer (FireBrowse)GAREM2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)150946
GTEX Portal (Tissue expression)GAREM2
Human Protein AtlasENSG00000157833-GAREM2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ75VX8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ75VX8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ75VX8
Splice isoforms : SwissVarQ75VX8
PhosPhoSitePlusQ75VX8
Domains : Interpro (EBI)CABIT_dom    SAM/pointed   
Domain families : Pfam (Sanger)CABIT (PF12736)   
Domain families : Pfam (NCBI)pfam12736   
Conserved Domain (NCBI)GAREM2
DMDM Disease mutations150946
Blocks (Seattle)GAREM2
SuperfamilyQ75VX8
Human Protein Atlas [tissue]ENSG00000157833-GAREM2 [tissue]
Peptide AtlasQ75VX8
IPIIPI00302557   IPI01009275   IPI00742896   
Protein Interaction databases
DIP (DOE-UCLA)Q75VX8
IntAct (EBI)Q75VX8
FunCoupENSG00000157833
BioGRIDGAREM2
STRING (EMBL)GAREM2
ZODIACGAREM2
Ontologies - Pathways
QuickGOQ75VX8
Ontology : AmiGOextracellular exosome  
Ontology : EGO-EBIextracellular exosome  
NDEx NetworkGAREM2
Atlas of Cancer Signalling NetworkGAREM2
Wikipedia pathwaysGAREM2
Orthology - Evolution
OrthoDB150946
GeneTree (enSembl)ENSG00000157833
Phylogenetic Trees/Animal Genes : TreeFamGAREM2
HOVERGENQ75VX8
HOGENOMQ75VX8
Homologs : HomoloGeneGAREM2
Homology/Alignments : Family Browser (UCSC)GAREM2
Gene fusions - Rearrangements
Tumor Fusion PortalGAREM2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGAREM2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GAREM2
dbVarGAREM2
ClinVarGAREM2
1000_GenomesGAREM2 
Exome Variant ServerGAREM2
ExAC (Exome Aggregation Consortium)ENSG00000157833
GNOMAD BrowserENSG00000157833
Genetic variants : HAPMAP150946
Genomic Variants (DGV)GAREM2 [DGVbeta]
DECIPHERGAREM2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGAREM2 
Mutations
ICGC Data PortalGAREM2 
TCGA Data PortalGAREM2 
Broad Tumor PortalGAREM2
OASIS PortalGAREM2 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDGAREM2
BioMutasearch GAREM2
DgiDB (Drug Gene Interaction Database)GAREM2
DoCM (Curated mutations)GAREM2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GAREM2 (select a term)
intoGenGAREM2
Cancer3DGAREM2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETGAREM2
MedgenGAREM2
Genetic Testing Registry GAREM2
NextProtQ75VX8 [Medical]
TSGene150946
GENETestsGAREM2
Target ValidationGAREM2
Huge Navigator GAREM2 [HugePedia]
snp3D : Map Gene to Disease150946
BioCentury BCIQGAREM2
ClinGenGAREM2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD150946
Chemical/Pharm GKB GenePA142671865
Clinical trialGAREM2
Miscellaneous
canSAR (ICR)GAREM2 (select the gene name)
Probes
Litterature
PubMed7 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGAREM2
EVEXGAREM2
GoPubMedGAREM2
iHOPGAREM2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 13:04:35 CET 2017

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