GATA5 (GATA binding protein 5)

2007-02-01  

Identity

HGNC
LOCATION
20q13.33
LOCUSID
ALIAS
CHTD5,GATAS,bB379O24.1

Other Information

Locus ID:

NCBI: 140628
MIM: 611496
HGNC: 15802
Ensembl: ENSG00000130700

Variants:

dbSNP: 140628
ClinVar: 140628
TCGA: ENSG00000130700
COSMIC: GATA5

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000130700ENST00000252997Q9BWX5

Expression (GTEx)

0
5
10
15
20
25
30

Pathways

PathwaySourceExternal ID
HemostasisREACTOMER-HSA-109582
Factors involved in megakaryocyte development and platelet productionREACTOMER-HSA-983231

References

Pubmed IDYearTitleCitations
146123892003GATA-4 and GATA-5 transcription factor genes and potential downstream antitumor target genes are epigenetically silenced in colorectal and gastric cancer.81
195091522009GATA4 and GATA5 are potential tumor suppressors and biomarkers in colorectal cancer.64
155856252004Hypermethylation of the GATA genes in lung cancer.46
226411492012Rare non-synonymous variations in the transcriptional activation domains of GATA5 in bicuspid aortic valve disease.32
168238492006Hypermethylation of the GATA gene family in esophageal cancer.23
202221622010Methylation of GATA-4 and GATA-5 and development of sporadic gastric carcinomas.23
247963702014Rare GATA5 sequence variants identified in individuals with bicuspid aortic valve.23
246388952014GATA5 loss-of-function mutations associated with congenital bicuspid aortic valve.19
163377382006Involvement of GATA-4/-5 transcription factors in ovarian carcinogenesis.18
257595302015Combined detection of plasma GATA5 and SFRP2 methylation is a valid noninvasive biomarker for colorectal cancer and adenomas.17

Citation

Dessen P

GATA5 (GATA binding protein 5)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/43802/gata5