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GATAD2A (GATA zinc finger domain containing 2A)

Identity

Alias_symbol (synonym)p66alpha
Other alias
HGNC (Hugo) GATAD2A
LocusID (NCBI) 54815
Atlas_Id 54325
Location 19p13.11  [Link to chromosome band 19p13]
Location_base_pair Starts at 19576149 and ends at 19619741 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
GATAD2A (19p13.11) / GATAD2A (19p13.11)GATAD2A (19p13.11) / PRDM2 (1p36.21)GATAD2A (19p13.11) / PRKACA (19p13.12)
GATAD2A (19p13.11) / ZC3H18 (16q24.2)NFIX (19p13.2) / GATAD2A (19p13.11)PMPCA (9q34.3) / GATAD2A (19p13.11)
GATAD2A 19p13.11 / PRKACA 19p13.12NFIX 19p13.2 / GATAD2A 19p13.11

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  Lung: Translocations in Small Cell Carcinoma


External links

Nomenclature
HGNC (Hugo)GATAD2A   29989
Cards
Entrez_Gene (NCBI)GATAD2A  54815  GATA zinc finger domain containing 2A
Aliasesp66alpha
GeneCards (Weizmann)GATAD2A
Ensembl hg19 (Hinxton)ENSG00000167491 [Gene_View]  chr19:19576149-19619741 [Contig_View]  GATAD2A [Vega]
Ensembl hg38 (Hinxton)ENSG00000167491 [Gene_View]  chr19:19576149-19619741 [Contig_View]  GATAD2A [Vega]
ICGC DataPortalENSG00000167491
TCGA cBioPortalGATAD2A
AceView (NCBI)GATAD2A
Genatlas (Paris)GATAD2A
WikiGenes54815
SOURCE (Princeton)GATAD2A
Genetics Home Reference (NIH)GATAD2A
Genomic and cartography
GoldenPath hg19 (UCSC)GATAD2A  -     chr19:19576149-19619741 +  19p13.11   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)GATAD2A  -     19p13.11   [Description]    (hg38-Dec_2013)
EnsemblGATAD2A - 19p13.11 [CytoView hg19]  GATAD2A - 19p13.11 [CytoView hg38]
Mapping of homologs : NCBIGATAD2A [Mapview hg19]  GATAD2A [Mapview hg38]
OMIM614997   
Gene and transcription
Genbank (Entrez)AK000092 AK024670 AK125974 AK225198 AK296781
RefSeq transcript (Entrez)NM_001300946 NM_017660
RefSeq genomic (Entrez)NC_000019 NC_018930 NT_011295 NW_004929414
Consensus coding sequences : CCDS (NCBI)GATAD2A
Cluster EST : UnigeneHs.118964 [ NCBI ]
CGAP (NCI)Hs.118964
Alternative Splicing GalleryENSG00000167491
Gene ExpressionGATAD2A [ NCBI-GEO ]   GATAD2A [ EBI - ARRAY_EXPRESS ]   GATAD2A [ SEEK ]   GATAD2A [ MEM ]
Gene Expression Viewer (FireBrowse)GATAD2A [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)54815
GTEX Portal (Tissue expression)GATAD2A
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ86YP4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ86YP4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ86YP4
Splice isoforms : SwissVarQ86YP4
PhosPhoSitePlusQ86YP4
Domaine pattern : Prosite (Expaxy)GATA_ZN_FINGER_1 (PS00344)    GATA_ZN_FINGER_2 (PS50114)   
Domains : Interpro (EBI)P66_CC    Znf_GATA    Znf_NHR/GATA   
Domain families : Pfam (Sanger)GATA (PF00320)    P66_CC (PF16563)   
Domain families : Pfam (NCBI)pfam00320    pfam16563   
Conserved Domain (NCBI)GATAD2A
DMDM Disease mutations54815
Blocks (Seattle)GATAD2A
PDB (SRS)2L2L   
PDB (PDBSum)2L2L   
PDB (IMB)2L2L   
PDB (RSDB)2L2L   
Structural Biology KnowledgeBase2L2L   
SCOP (Structural Classification of Proteins)2L2L   
CATH (Classification of proteins structures)2L2L   
SuperfamilyQ86YP4
Human Protein AtlasENSG00000167491
Peptide AtlasQ86YP4
HPRD11741
IPIIPI00410330   IPI00444526   IPI01012784   IPI00478128   IPI00892860   IPI00892770   IPI00892992   IPI00892840   IPI00892710   
Protein Interaction databases
DIP (DOE-UCLA)Q86YP4
IntAct (EBI)Q86YP4
FunCoupENSG00000167491
BioGRIDGATAD2A
STRING (EMBL)GATAD2A
ZODIACGATAD2A
Ontologies - Pathways
QuickGOQ86YP4
Ontology : AmiGOnegative regulation of transcription from RNA polymerase II promoter  RNA polymerase II regulatory region sequence-specific DNA binding  transcription factor activity, sequence-specific DNA binding  protein binding  nucleus  nucleoplasm  DNA methylation  transcription, DNA-templated  zinc ion binding  NuRD complex  nuclear speck  protein binding, bridging  negative regulation of transcription, DNA-templated  
Ontology : EGO-EBInegative regulation of transcription from RNA polymerase II promoter  RNA polymerase II regulatory region sequence-specific DNA binding  transcription factor activity, sequence-specific DNA binding  protein binding  nucleus  nucleoplasm  DNA methylation  transcription, DNA-templated  zinc ion binding  NuRD complex  nuclear speck  protein binding, bridging  negative regulation of transcription, DNA-templated  
NDEx NetworkGATAD2A
Atlas of Cancer Signalling NetworkGATAD2A
Wikipedia pathwaysGATAD2A
Orthology - Evolution
OrthoDB54815
GeneTree (enSembl)ENSG00000167491
Phylogenetic Trees/Animal Genes : TreeFamGATAD2A
HOVERGENQ86YP4
HOGENOMQ86YP4
Homologs : HomoloGeneGATAD2A
Homology/Alignments : Family Browser (UCSC)GATAD2A
Gene fusions - Rearrangements
Fusion : MitelmanGATAD2A/PRKACA [19p13.11/19p13.12]  
Fusion : MitelmanNFIX/GATAD2A [19p13.2/19p13.11]  [t(19;19)(p13;p13)]  
Fusion: TCGAGATAD2A 19p13.11 PRKACA 19p13.12 BRCA
Fusion: TCGANFIX 19p13.2 GATAD2A 19p13.11 THCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGATAD2A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GATAD2A
dbVarGATAD2A
ClinVarGATAD2A
1000_GenomesGATAD2A 
Exome Variant ServerGATAD2A
ExAC (Exome Aggregation Consortium)GATAD2A (select the gene name)
Genetic variants : HAPMAP54815
Genomic Variants (DGV)GATAD2A [DGVbeta]
DECIPHER (Syndromes)19:19576149-19619741  ENSG00000167491
CONAN: Copy Number AnalysisGATAD2A 
Mutations
ICGC Data PortalGATAD2A 
TCGA Data PortalGATAD2A 
Broad Tumor PortalGATAD2A
OASIS PortalGATAD2A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGATAD2A  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGATAD2A
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GATAD2A
DgiDB (Drug Gene Interaction Database)GATAD2A
DoCM (Curated mutations)GATAD2A (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GATAD2A (select a term)
intoGenGATAD2A
Cancer3DGATAD2A(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM614997   
Orphanet
MedgenGATAD2A
Genetic Testing Registry GATAD2A
NextProtQ86YP4 [Medical]
TSGene54815
GENETestsGATAD2A
Huge Navigator GATAD2A [HugePedia]
snp3D : Map Gene to Disease54815
BioCentury BCIQGATAD2A
ClinGenGATAD2A
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD54815
Chemical/Pharm GKB GenePA142671746
Clinical trialGATAD2A
Miscellaneous
canSAR (ICR)GATAD2A (select the gene name)
Probes
Litterature
PubMed33 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGATAD2A
EVEXGATAD2A
GoPubMedGATAD2A
iHOPGATAD2A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Mar 14 13:07:07 CET 2017

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