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GATAD2B (GATA zinc finger domain containing 2B)

Identity

Alias (NCBI)GANDS
MRD18
P66beta
p68
HGNC (Hugo) GATAD2B
HGNC Alias symbP66beta
HGNC Alias nametranscription repressor p66 beta component of the MeCP1 complex
LocusID (NCBI) 57459
Atlas_Id 54326
Location 1q21.3  [Link to chromosome band 1q21]
Location_base_pair Starts at 153804727 and ends at 153922972 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ASH1L (1q22) / GATAD2B (1q21.3)FBXO34 (14q22.3) / GATAD2B (1q21.3)GATAD2B (1q21.3) / ASH1L (1q22)
GATAD2B (1q21.3) / CRTC2 (1q21.3)GATAD2B (1q21.3) / DPY19L2P2 (7q22.1)GATAD2B (1q21.3) / ERI3 (1p34.1)
GATAD2B (1q21.3) / GATAD2B (1q21.3)GATAD2B (1q21.3) / KCNN3 (1q21.3)GATAD2B (1q21.3) / NUP210L (1q21.3)
GATAD2B (1q21.3) / PRKAB2 (1q21.1)GATAD2B (1q21.3) / PTRF (17q21.2)GATAD2B (1q21.3) / RP11-574F21.3 ()
GATAD2B (1q21.3) / SLC9C2 (1q25.1)GATAD2B (1q21.3) / TNFSF18 (1q25.1)GATAD2B (1q21.3) / TTTY14 (Yq11.222)
GATAD2B (1q21.3) / USP7 (16p13.2)MAP7 (6q23.3) / GATAD2B (1q21.3)RPN1 (3q21.3) / GATAD2B (1q21.3)
ZSWIM6 (5q12.1) / GATAD2B (1q21.3)ASH1L 1q22 / GATAD2B 1q21.3GATAD2B 1q21.3 / ASH1L 1q22
GATAD2B 1q21.3 / CRTC2 1q21.3GATAD2B 1q21.3 / ERI3 1p34.1GATAD2B 1q21.3 / KCNN3 1q21.3
GATAD2B 1q21.3 / NUP210L 1q21.3GATAD2B 1q21.3 RP11-574F21.3GATAD2B 1q21.3 SLC9A11
GATAD2B 1q21.3 / TNFSF18 1q25.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)GATAD2B   30778
Cards
Entrez_Gene (NCBI)GATAD2B    GATA zinc finger domain containing 2B
AliasesGANDS; MRD18; P66beta; p68
GeneCards (Weizmann)GATAD2B
Ensembl hg19 (Hinxton)ENSG00000143614 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000143614 [Gene_View]  ENSG00000143614 [Sequence]  chr1:153804727-153922972 [Contig_View]  GATAD2B [Vega]
ICGC DataPortalENSG00000143614
TCGA cBioPortalGATAD2B
AceView (NCBI)GATAD2B
Genatlas (Paris)GATAD2B
SOURCE (Princeton)GATAD2B
Genetics Home Reference (NIH)GATAD2B
Genomic and cartography
GoldenPath hg38 (UCSC)GATAD2B  -     chr1:153804727-153922972 -  1q21.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GATAD2B  -     1q21.3   [Description]    (hg19-Feb_2009)
GoldenPathGATAD2B - 1q21.3 [CytoView hg19]  GATAD2B - 1q21.3 [CytoView hg38]
ImmunoBaseENSG00000143614
Genome Data Viewer NCBIGATAD2B [Mapview hg19]  
OMIM614998   615074   
Gene and transcription
Genbank (Entrez)AB032976 AF411836 AI701819 AK094665 BC069419
RefSeq transcript (Entrez)NM_020699
Consensus coding sequences : CCDS (NCBI)GATAD2B
Gene ExpressionGATAD2B [ NCBI-GEO ]   GATAD2B [ EBI - ARRAY_EXPRESS ]   GATAD2B [ SEEK ]   GATAD2B [ MEM ]
Gene Expression Viewer (FireBrowse)GATAD2B [ Firebrowse - Broad ]
GenevisibleExpression of GATAD2B in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)57459
GTEX Portal (Tissue expression)GATAD2B
Human Protein AtlasENSG00000143614-GATAD2B [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8WXI9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8WXI9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8WXI9
PhosPhoSitePlusQ8WXI9
Domaine pattern : Prosite (Expaxy)GATA_ZN_FINGER_2 (PS50114)   
Domains : Interpro (EBI)P66    P66_CC    Znf_GATA    Znf_NHR/GATA   
Domain families : Pfam (Sanger)GATA (PF00320)    P66_CC (PF16563)   
Domain families : Pfam (NCBI)pfam00320    pfam16563   
Conserved Domain (NCBI)GATAD2B
SuperfamilyQ8WXI9
AlphaFold pdb e-kbQ8WXI9   
Human Protein Atlas [tissue]ENSG00000143614-GATAD2B [tissue]
HPRD15094
Protein Interaction databases
DIP (DOE-UCLA)Q8WXI9
IntAct (EBI)Q8WXI9
BioGRIDGATAD2B
STRING (EMBL)GATAD2B
ZODIACGATAD2B
Ontologies - Pathways
QuickGOQ8WXI9
Ontology : AmiGOnegative regulation of transcription by RNA polymerase II  chromatin  protein binding  nucleoplasm  zinc ion binding  NuRD complex  nuclear speck  nucleosomal DNA binding  protein-containing complex  ATP-dependent chromatin remodeling  sequence-specific DNA binding  
Ontology : EGO-EBInegative regulation of transcription by RNA polymerase II  chromatin  protein binding  nucleoplasm  zinc ion binding  NuRD complex  nuclear speck  nucleosomal DNA binding  protein-containing complex  ATP-dependent chromatin remodeling  sequence-specific DNA binding  
NDEx NetworkGATAD2B
Atlas of Cancer Signalling NetworkGATAD2B
Wikipedia pathwaysGATAD2B
Orthology - Evolution
OrthoDB57459
GeneTree (enSembl)ENSG00000143614
Phylogenetic Trees/Animal Genes : TreeFamGATAD2B
Homologs : HomoloGeneGATAD2B
Homology/Alignments : Family Browser (UCSC)GATAD2B
Gene fusions - Rearrangements
Fusion : MitelmanASH1L/GATAD2B [1q22/1q21.3]  
Fusion : MitelmanGATAD2B/ASH1L [1q21.3/1q22]  
Fusion : MitelmanGATAD2B/CRTC2 [1q21.3/1q21.3]  
Fusion : MitelmanGATAD2B/ERI3 [1q21.3/1p34.1]  
Fusion : MitelmanGATAD2B/KCNN3 [1q21.3/1q21.3]  
Fusion : MitelmanGATAD2B/NUP210L [1q21.3/1q21.3]  
Fusion : MitelmanGATAD2B/PRKAB2 [1q21.3/1q21.1]  
Fusion : MitelmanGATAD2B/SLC9C2 [1q21.3/1q25.1]  
Fusion : MitelmanGATAD2B/TNFSF18 [1q21.3/1q25.1]  
Fusion : QuiverGATAD2B
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGATAD2B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GATAD2B
dbVarGATAD2B
ClinVarGATAD2B
MonarchGATAD2B
1000_GenomesGATAD2B 
Exome Variant ServerGATAD2B
GNOMAD BrowserENSG00000143614
Varsome BrowserGATAD2B
ACMGGATAD2B variants
VarityQ8WXI9
Genomic Variants (DGV)GATAD2B [DGVbeta]
DECIPHERGATAD2B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGATAD2B 
Mutations
ICGC Data PortalGATAD2B 
TCGA Data PortalGATAD2B 
Broad Tumor PortalGATAD2B
OASIS PortalGATAD2B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGATAD2B  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DGATAD2B
Mutations and Diseases : HGMDGATAD2B
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaGATAD2B
DgiDB (Drug Gene Interaction Database)GATAD2B
DoCM (Curated mutations)GATAD2B
CIViC (Clinical Interpretations of Variants in Cancer)GATAD2B
Cancer3DGATAD2B
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM614998    615074   
Orphanet22339   
DisGeNETGATAD2B
MedgenGATAD2B
Genetic Testing Registry GATAD2B
NextProtQ8WXI9 [Medical]
GENETestsGATAD2B
Target ValidationGATAD2B
Huge Navigator GATAD2B [HugePedia]
ClinGenGATAD2B
Clinical trials, drugs, therapy
MyCancerGenomeGATAD2B
Protein Interactions : CTDGATAD2B
Pharm GKB GenePA142671747
PharosQ8WXI9
Clinical trialGATAD2B
Miscellaneous
canSAR (ICR)GATAD2B
HarmonizomeGATAD2B
DataMed IndexGATAD2B
Probes
Litterature
PubMed103 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXGATAD2B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Oct 4 15:10:27 CEST 2021

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