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GATM (glycine amidinotransferase)

Identity

Alias_symbol (synonym)AGAT
Other aliasAT
CCDS3
HGNC (Hugo) GATM
LocusID (NCBI) 2628
Atlas_Id 55531
Location 1q21.3  [Link to chromosome band 1q21]
Location_base_pair Starts at 45361124 and ends at 45378782 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
GATM (15q21.1) / BRAF (7q34)GATM (15q21.1) / DDX3X (Xp11.4)GATM (15q21.1) / TSEN2 (3p25.2)
WSB1 (17q11.1) / GATM (15q21.1)GATM BRAF 7q34

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)GATM   4175
Cards
Entrez_Gene (NCBI)GATM  2628  glycine amidinotransferase
AliasesAGAT; AT; CCDS3
GeneCards (Weizmann)GATM
Ensembl hg19 (Hinxton)ENSG00000171766 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000171766 [Gene_View]  ENSG00000171766 [Sequence]  chr15:45361124-45378782 [Contig_View]  GATM [Vega]
ICGC DataPortalENSG00000171766
TCGA cBioPortalGATM
AceView (NCBI)GATM
Genatlas (Paris)GATM
WikiGenes2628
SOURCE (Princeton)GATM
Genetics Home Reference (NIH)GATM
Genomic and cartography
GoldenPath hg38 (UCSC)GATM  -     chr15:45361124-45378782 -  1q21.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GATM  -     1q21.3   [Description]    (hg19-Feb_2009)
EnsemblGATM - 1q21.3 [CytoView hg19]  GATM - 1q21.3 [CytoView hg38]
Mapping of homologs : NCBIGATM [Mapview hg19]  GATM [Mapview hg38]
OMIM602360   612718   
Gene and transcription
Genbank (Entrez)AI253042 AK098055 AK098393 AK223585 AK294995
RefSeq transcript (Entrez)NM_001321015 NM_001482
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GATM
Cluster EST : UnigeneHs.729565 [ NCBI ]
CGAP (NCI)Hs.729565
Alternative Splicing GalleryENSG00000171766
Gene ExpressionGATM [ NCBI-GEO ]   GATM [ EBI - ARRAY_EXPRESS ]   GATM [ SEEK ]   GATM [ MEM ]
Gene Expression Viewer (FireBrowse)GATM [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2628
GTEX Portal (Tissue expression)GATM
Human Protein AtlasENSG00000171766-GATM [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP50440   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP50440  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP50440
Splice isoforms : SwissVarP50440
PhosPhoSitePlusP50440
Domains : Interpro (EBI)AmidinoTrfase   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)GATM
DMDM Disease mutations2628
Blocks (Seattle)GATM
PDB (SRS)1JDW    1JDX    2JDW    2JDX    3JDW    4JDW    5JDW    6JDW    7JDW    8JDW    9JDW   
PDB (PDBSum)1JDW    1JDX    2JDW    2JDX    3JDW    4JDW    5JDW    6JDW    7JDW    8JDW    9JDW   
PDB (IMB)1JDW    1JDX    2JDW    2JDX    3JDW    4JDW    5JDW    6JDW    7JDW    8JDW    9JDW   
PDB (RSDB)1JDW    1JDX    2JDW    2JDX    3JDW    4JDW    5JDW    6JDW    7JDW    8JDW    9JDW   
Structural Biology KnowledgeBase1JDW    1JDX    2JDW    2JDX    3JDW    4JDW    5JDW    6JDW    7JDW    8JDW    9JDW   
SCOP (Structural Classification of Proteins)1JDW    1JDX    2JDW    2JDX    3JDW    4JDW    5JDW    6JDW    7JDW    8JDW    9JDW   
CATH (Classification of proteins structures)1JDW    1JDX    2JDW    2JDX    3JDW    4JDW    5JDW    6JDW    7JDW    8JDW    9JDW   
SuperfamilyP50440
Human Protein Atlas [tissue]ENSG00000171766-GATM [tissue]
Peptide AtlasP50440
HPRD03838
IPIIPI00032103   IPI00216279   IPI00970843   
Protein Interaction databases
DIP (DOE-UCLA)P50440
IntAct (EBI)P50440
FunCoupENSG00000171766
BioGRIDGATM
STRING (EMBL)GATM
ZODIACGATM
Ontologies - Pathways
QuickGOP50440
Ontology : AmiGOmitochondrion  mitochondrion  mitochondrial inner membrane  mitochondrial intermembrane space  mitochondrial intermembrane space  creatine metabolic process  creatine metabolic process  creatine biosynthetic process  creatine biosynthetic process  creatine biosynthetic process  multicellular organism development  learning or memory  muscle atrophy  amidinotransferase activity  glycine amidinotransferase activity  glycine amidinotransferase activity  extracellular exosome  
Ontology : EGO-EBImitochondrion  mitochondrion  mitochondrial inner membrane  mitochondrial intermembrane space  mitochondrial intermembrane space  creatine metabolic process  creatine metabolic process  creatine biosynthetic process  creatine biosynthetic process  creatine biosynthetic process  multicellular organism development  learning or memory  muscle atrophy  amidinotransferase activity  glycine amidinotransferase activity  glycine amidinotransferase activity  extracellular exosome  
Pathways : KEGGGlycine, serine and threonine metabolism    Arginine and proline metabolism   
NDEx NetworkGATM
Atlas of Cancer Signalling NetworkGATM
Wikipedia pathwaysGATM
Orthology - Evolution
OrthoDB2628
GeneTree (enSembl)ENSG00000171766
Phylogenetic Trees/Animal Genes : TreeFamGATM
HOVERGENP50440
HOGENOMP50440
Homologs : HomoloGeneGATM
Homology/Alignments : Family Browser (UCSC)GATM
Gene fusions - Rearrangements
Fusion : QuiverGATM
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGATM [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GATM
dbVarGATM
ClinVarGATM
1000_GenomesGATM 
Exome Variant ServerGATM
ExAC (Exome Aggregation Consortium)ENSG00000171766
GNOMAD BrowserENSG00000171766
Varsome BrowserGATM
Genetic variants : HAPMAP2628
Genomic Variants (DGV)GATM [DGVbeta]
DECIPHERGATM [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGATM 
Mutations
ICGC Data PortalGATM 
TCGA Data PortalGATM 
Broad Tumor PortalGATM
OASIS PortalGATM [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGATM  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGATM
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
BioMutasearch GATM
DgiDB (Drug Gene Interaction Database)GATM
DoCM (Curated mutations)GATM (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GATM (select a term)
intoGenGATM
Cancer3DGATM(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602360    612718   
Orphanet10393   
DisGeNETGATM
MedgenGATM
Genetic Testing Registry GATM
NextProtP50440 [Medical]
TSGene2628
GENETestsGATM
Target ValidationGATM
Huge Navigator GATM [HugePedia]
snp3D : Map Gene to Disease2628
BioCentury BCIQGATM
ClinGenGATM
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2628
Chemical/Pharm GKB GenePA28590
Clinical trialGATM
Miscellaneous
canSAR (ICR)GATM (select the gene name)
Probes
Litterature
PubMed44 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGATM
EVEXGATM
GoPubMedGATM
iHOPGATM
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Jul 30 14:54:24 CEST 2018
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