Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2634
MIM: 600412
HGNC: 4183
Ensembl: ENSG00000162645
Variants:
dbSNP: 2634
ClinVar: 2634
TCGA: ENSG00000162645
COSMIC: GBP2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000162645 | ENST00000370466 | P32456 |
| ENSG00000162645 | ENST00000464839 | P32456 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38636926 | 2024 | GBP2 inhibits pathological angiogenesis in the retina via the AKT/mTOR/VEGFA axis. | 0 |
| 38636926 | 2024 | GBP2 inhibits pathological angiogenesis in the retina via the AKT/mTOR/VEGFA axis. | 0 |
| 36346541 | 2023 | Guanine nucleotide-binding protein 2, GNBP2, accelerates the progression of clear cell renal cell carcinoma via regulation of STAT3 signaling transduction pathway. | 0 |
| 36460216 | 2023 | Differential expression of interferon inducible protein: Guanylate binding protein (GBP1 & GBP2) in severe dengue. | 2 |
| 36609599 | 2023 | Dnmt1/Tet2-mediated changes in Cmip methylation regulate the development of nonalcoholic fatty liver disease by controlling the Gbp2-Pparγ-CD36 axis. | 4 |
| 36660930 | 2023 | GBP2 promotes clear cell renal cell carcinoma progression through immune infiltration and regulation of PD‑L1 expression via STAT1 signaling. | 9 |
| 37622120 | 2023 | GBP2 promotes M1 macrophage polarization by activating the notch1 signaling pathway in diabetic nephropathy. | 2 |
| 36346541 | 2023 | Guanine nucleotide-binding protein 2, GNBP2, accelerates the progression of clear cell renal cell carcinoma via regulation of STAT3 signaling transduction pathway. | 0 |
| 36460216 | 2023 | Differential expression of interferon inducible protein: Guanylate binding protein (GBP1 & GBP2) in severe dengue. | 2 |
| 36609599 | 2023 | Dnmt1/Tet2-mediated changes in Cmip methylation regulate the development of nonalcoholic fatty liver disease by controlling the Gbp2-Pparγ-CD36 axis. | 4 |
| 36660930 | 2023 | GBP2 promotes clear cell renal cell carcinoma progression through immune infiltration and regulation of PD‑L1 expression via STAT1 signaling. | 9 |
| 37622120 | 2023 | GBP2 promotes M1 macrophage polarization by activating the notch1 signaling pathway in diabetic nephropathy. | 2 |
| 35383115 | 2022 | Subtyping of microsatellite stability colorectal cancer reveals guanylate binding protein 2 (GBP2) as a potential immunotherapeutic target. | 16 |
| 35543550 | 2022 | Lower Expression of GBP2 Associated With Less Immune Cell Infiltration and Poor Prognosis in Skin Cutaneous Melanoma (SKCM). | 5 |
| 36115937 | 2022 | GBP2 acts as a member of the interferon signalling pathway in lupus nephritis. | 2 |
Citation
Dessen P
GBP2 (guanylate binding protein 2)
Atlas Genet Cytogenet Oncol Haematol. 2003-06-01
Online version: http://atlasgeneticsoncology.org/gene/40692/gbp2
