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GBP4 (guanylate binding protein 4)

Identity

Alias_symbol (synonym)Mpa2
Other alias
HGNC (Hugo) GBP4
LocusID (NCBI) 115361
Atlas_Id 63727
Location 1p22.2  [Link to chromosome band 1p22]
Location_base_pair Starts at 89181148 and ends at 89198950 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
FTL (19q13.33) / GBP4 (1p22.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GBP4   20480
Cards
Entrez_Gene (NCBI)GBP4  115361  guanylate binding protein 4
AliasesMpa2
GeneCards (Weizmann)GBP4
Ensembl hg19 (Hinxton)ENSG00000162654 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000162654 [Gene_View]  chr1:89181148-89198950 [Contig_View]  GBP4 [Vega]
ICGC DataPortalENSG00000162654
TCGA cBioPortalGBP4
AceView (NCBI)GBP4
Genatlas (Paris)GBP4
WikiGenes115361
SOURCE (Princeton)GBP4
Genetics Home Reference (NIH)GBP4
Genomic and cartography
GoldenPath hg38 (UCSC)GBP4  -     chr1:89181148-89198950 -  1p22.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GBP4  -     1p22.2   [Description]    (hg19-Feb_2009)
EnsemblGBP4 - 1p22.2 [CytoView hg19]  GBP4 - 1p22.2 [CytoView hg38]
Mapping of homologs : NCBIGBP4 [Mapview hg19]  GBP4 [Mapview hg38]
OMIM612466   
Gene and transcription
Genbank (Entrez)AF288814 AK131094 AK304245 AK312417 AL832576
RefSeq transcript (Entrez)NM_052941
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GBP4
Cluster EST : UnigeneHs.409925 [ NCBI ]
CGAP (NCI)Hs.409925
Alternative Splicing GalleryENSG00000162654
Gene ExpressionGBP4 [ NCBI-GEO ]   GBP4 [ EBI - ARRAY_EXPRESS ]   GBP4 [ SEEK ]   GBP4 [ MEM ]
Gene Expression Viewer (FireBrowse)GBP4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)115361
GTEX Portal (Tissue expression)GBP4
Human Protein AtlasENSG00000162654-GBP4 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96PP9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96PP9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96PP9
Splice isoforms : SwissVarQ96PP9
PhosPhoSitePlusQ96PP9
Domaine pattern : Prosite (Expaxy)G_GB1_RHD3 (PS51715)   
Domains : Interpro (EBI)G_GB1_RHD3_dom    Guanylate-bd_C    Guanylate-bd_N    P-loop_NTPase   
Domain families : Pfam (Sanger)GBP (PF02263)    GBP_C (PF02841)   
Domain families : Pfam (NCBI)pfam02263    pfam02841   
Conserved Domain (NCBI)GBP4
DMDM Disease mutations115361
Blocks (Seattle)GBP4
SuperfamilyQ96PP9
Human Protein Atlas [tissue]ENSG00000162654-GBP4 [tissue]
Peptide AtlasQ96PP9
HPRD13570
IPIIPI00419541   
Protein Interaction databases
DIP (DOE-UCLA)Q96PP9
IntAct (EBI)Q96PP9
FunCoupENSG00000162654
BioGRIDGBP4
STRING (EMBL)GBP4
ZODIACGBP4
Ontologies - Pathways
QuickGOQ96PP9
Ontology : AmiGOGolgi membrane  GTPase activity  GTP binding  nucleus  perinuclear region of cytoplasm  
Ontology : EGO-EBIGolgi membrane  GTPase activity  GTP binding  nucleus  perinuclear region of cytoplasm  
NDEx NetworkGBP4
Atlas of Cancer Signalling NetworkGBP4
Wikipedia pathwaysGBP4
Orthology - Evolution
OrthoDB115361
GeneTree (enSembl)ENSG00000162654
Phylogenetic Trees/Animal Genes : TreeFamGBP4
HOVERGENQ96PP9
HOGENOMQ96PP9
Homologs : HomoloGeneGBP4
Homology/Alignments : Family Browser (UCSC)GBP4
Gene fusions - Rearrangements
Tumor Fusion PortalGBP4
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGBP4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GBP4
dbVarGBP4
ClinVarGBP4
1000_GenomesGBP4 
Exome Variant ServerGBP4
ExAC (Exome Aggregation Consortium)ENSG00000162654
GNOMAD BrowserENSG00000162654
Genetic variants : HAPMAP115361
Genomic Variants (DGV)GBP4 [DGVbeta]
DECIPHERGBP4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGBP4 
Mutations
ICGC Data PortalGBP4 
TCGA Data PortalGBP4 
Broad Tumor PortalGBP4
OASIS PortalGBP4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGBP4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGBP4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GBP4
DgiDB (Drug Gene Interaction Database)GBP4
DoCM (Curated mutations)GBP4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GBP4 (select a term)
intoGenGBP4
Cancer3DGBP4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612466   
Orphanet
DisGeNETGBP4
MedgenGBP4
Genetic Testing Registry GBP4
NextProtQ96PP9 [Medical]
TSGene115361
GENETestsGBP4
Target ValidationGBP4
Huge Navigator GBP4 [HugePedia]
snp3D : Map Gene to Disease115361
BioCentury BCIQGBP4
ClinGenGBP4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD115361
Chemical/Pharm GKB GenePA134959399
Clinical trialGBP4
Miscellaneous
canSAR (ICR)GBP4 (select the gene name)
Probes
Litterature
PubMed9 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGBP4
EVEXGBP4
GoPubMedGBP4
iHOPGBP4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 13:00:16 CET 2017

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