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GBP6 (guanylate binding protein family member 6)

Identity

Alias_namesguanylate binding protein family, member 6
Alias_symbol (synonym)DKFZp686G0786
Other alias-
HGNC (Hugo) GBP6
LocusID (NCBI) 163351
Atlas_Id 63728
Location 1p22.2  [Link to chromosome band 1p22]
Location_base_pair Starts at 89363877 and ends at 89388160 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
HS2ST1 (1p22.3) / GBP6 (1p22.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GBP6   25395
Cards
Entrez_Gene (NCBI)GBP6  163351  guanylate binding protein family member 6
Aliases
GeneCards (Weizmann)GBP6
Ensembl hg19 (Hinxton)ENSG00000183347 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000183347 [Gene_View]  chr1:89363877-89388160 [Contig_View]  GBP6 [Vega]
ICGC DataPortalENSG00000183347
TCGA cBioPortalGBP6
AceView (NCBI)GBP6
Genatlas (Paris)GBP6
WikiGenes163351
SOURCE (Princeton)GBP6
Genetics Home Reference (NIH)GBP6
Genomic and cartography
GoldenPath hg38 (UCSC)GBP6  -     chr1:89363877-89388160 +  1p22.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GBP6  -     1p22.2   [Description]    (hg19-Feb_2009)
EnsemblGBP6 - 1p22.2 [CytoView hg19]  GBP6 - 1p22.2 [CytoView hg38]
Mapping of homologs : NCBIGBP6 [Mapview hg19]  GBP6 [Mapview hg38]
OMIM612467   
Gene and transcription
Genbank (Entrez)AI199897 AK096454 AK131329 AK131356 AK290303
RefSeq transcript (Entrez)NM_001320257 NM_198460
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GBP6
Cluster EST : UnigeneHs.254338 [ NCBI ]
CGAP (NCI)Hs.254338
Alternative Splicing GalleryENSG00000183347
Gene ExpressionGBP6 [ NCBI-GEO ]   GBP6 [ EBI - ARRAY_EXPRESS ]   GBP6 [ SEEK ]   GBP6 [ MEM ]
Gene Expression Viewer (FireBrowse)GBP6 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)163351
GTEX Portal (Tissue expression)GBP6
Human Protein AtlasENSG00000183347-GBP6 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6ZN66   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6ZN66  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6ZN66
Splice isoforms : SwissVarQ6ZN66
PhosPhoSitePlusQ6ZN66
Domaine pattern : Prosite (Expaxy)G_GB1_RHD3 (PS51715)   
Domains : Interpro (EBI)G_GB1_RHD3_dom    Guanylate-bd_C    Guanylate-bd_N    P-loop_NTPase   
Domain families : Pfam (Sanger)GBP (PF02263)    GBP_C (PF02841)   
Domain families : Pfam (NCBI)pfam02263    pfam02841   
Conserved Domain (NCBI)GBP6
DMDM Disease mutations163351
Blocks (Seattle)GBP6
SuperfamilyQ6ZN66
Human Protein Atlas [tissue]ENSG00000183347-GBP6 [tissue]
Peptide AtlasQ6ZN66
HPRD13572
IPIIPI00375746   IPI01009416   IPI00910685   IPI00879248   
Protein Interaction databases
DIP (DOE-UCLA)Q6ZN66
IntAct (EBI)Q6ZN66
FunCoupENSG00000183347
BioGRIDGBP6
STRING (EMBL)GBP6
ZODIACGBP6
Ontologies - Pathways
QuickGOQ6ZN66
Ontology : AmiGOGTPase activity  GTP binding  immune response  defense response to bacterium  extracellular exosome  cellular response to interferon-gamma  
Ontology : EGO-EBIGTPase activity  GTP binding  immune response  defense response to bacterium  extracellular exosome  cellular response to interferon-gamma  
NDEx NetworkGBP6
Atlas of Cancer Signalling NetworkGBP6
Wikipedia pathwaysGBP6
Orthology - Evolution
OrthoDB163351
GeneTree (enSembl)ENSG00000183347
Phylogenetic Trees/Animal Genes : TreeFamGBP6
HOVERGENQ6ZN66
HOGENOMQ6ZN66
Homologs : HomoloGeneGBP6
Homology/Alignments : Family Browser (UCSC)GBP6
Gene fusions - Rearrangements
Fusion: Tumor Portal GBP6
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGBP6 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GBP6
dbVarGBP6
ClinVarGBP6
1000_GenomesGBP6 
Exome Variant ServerGBP6
ExAC (Exome Aggregation Consortium)ENSG00000183347
GNOMAD BrowserENSG00000183347
Genetic variants : HAPMAP163351
Genomic Variants (DGV)GBP6 [DGVbeta]
DECIPHERGBP6 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGBP6 
Mutations
ICGC Data PortalGBP6 
TCGA Data PortalGBP6 
Broad Tumor PortalGBP6
OASIS PortalGBP6 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGBP6  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGBP6
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GBP6
DgiDB (Drug Gene Interaction Database)GBP6
DoCM (Curated mutations)GBP6 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GBP6 (select a term)
intoGenGBP6
Cancer3DGBP6(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612467   
Orphanet
MedgenGBP6
Genetic Testing Registry GBP6
NextProtQ6ZN66 [Medical]
TSGene163351
GENETestsGBP6
Target ValidationGBP6
Huge Navigator GBP6 [HugePedia]
snp3D : Map Gene to Disease163351
BioCentury BCIQGBP6
ClinGenGBP6
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD163351
Chemical/Pharm GKB GenePA134964409
Clinical trialGBP6
Miscellaneous
canSAR (ICR)GBP6 (select the gene name)
Probes
Litterature
PubMed12 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGBP6
EVEXGBP6
GoPubMedGBP6
iHOPGBP6
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Nov 9 11:48:49 CET 2017

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