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GBX2 (gastrulation brain homeobox 2)

Identity

Other names-
HGNC (Hugo) GBX2
LocusID (NCBI) 2637
Atlas_Id 40693
Location 2q37.2  [Link to chromosome band 2q37]
Location_base_pair Starts at 237073879 and ends at 237076652 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GBX2   4186
Cards
Entrez_Gene (NCBI)GBX2  2637  gastrulation brain homeobox 2
Aliases
GeneCards (Weizmann)GBX2
Ensembl hg19 (Hinxton)ENSG00000168505 [Gene_View]  chr2:237073879-237076652 [Contig_View]  GBX2 [Vega]
Ensembl hg38 (Hinxton)ENSG00000168505 [Gene_View]  chr2:237073879-237076652 [Contig_View]  GBX2 [Vega]
ICGC DataPortalENSG00000168505
TCGA cBioPortalGBX2
AceView (NCBI)GBX2
Genatlas (Paris)GBX2
WikiGenes2637
SOURCE (Princeton)GBX2
Genomic and cartography
GoldenPath hg19 (UCSC)GBX2  -     chr2:237073879-237076652 -  2q37.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)GBX2  -     2q37.2   [Description]    (hg38-Dec_2013)
EnsemblGBX2 - 2q37.2 [CytoView hg19]  GBX2 - 2q37.2 [CytoView hg38]
Mapping of homologs : NCBIGBX2 [Mapview hg19]  GBX2 [Mapview hg38]
OMIM601135   
Gene and transcription
Genbank (Entrez)AA176205 AF118452 AK311262 BC137448 BC137449
RefSeq transcript (Entrez)NM_001301687 NM_001485
RefSeq genomic (Entrez)NC_000002 NC_018913 NT_005403 NW_004929306
Consensus coding sequences : CCDS (NCBI)GBX2
Cluster EST : UnigeneHs.735751 [ NCBI ]
CGAP (NCI)Hs.735751
Alternative Splicing GalleryENSG00000168505
Gene ExpressionGBX2 [ NCBI-GEO ]   GBX2 [ EBI - ARRAY_EXPRESS ]   GBX2 [ SEEK ]   GBX2 [ MEM ]
Gene Expression Viewer (FireBrowse)GBX2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2637
GTEX Portal (Tissue expression)GBX2
Protein : pattern, domain, 3D structure
UniProt/SwissProtP52951 (Uniprot)
NextProtP52951  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP52951
Splice isoforms : SwissVarP52951 (Swissvar)
PhosPhoSitePlusP52951
Domaine pattern : Prosite (Expaxy)HOMEOBOX_1 (PS00027)    HOMEOBOX_2 (PS50071)   
Domains : Interpro (EBI)GBX-2    Homeobox_CS    Homeobox_dom    Homeobox_metazoa    Homeodomain-like   
Domain families : Pfam (Sanger)Homeobox (PF00046)   
Domain families : Pfam (NCBI)pfam00046   
Domain families : Smart (EMBL)HOX (SM00389)  
DMDM Disease mutations2637
Blocks (Seattle)GBX2
SuperfamilyP52951
Human Protein AtlasENSG00000168505
Peptide AtlasP52951
HPRD03087
IPIIPI00006053   IPI01020826   
Protein Interaction databases
DIP (DOE-UCLA)P52951
IntAct (EBI)P52951
FunCoupENSG00000168505
BioGRIDGBX2
STRING (EMBL)GBX2
ZODIACGBX2
Ontologies - Pathways
QuickGOP52951
Ontology : AmiGORNA polymerase II core promoter sequence-specific DNA binding  transcriptional activator activity, RNA polymerase II transcription factor binding  patterning of blood vessels  neural crest cell migration  transcription factor activity, sequence-specific DNA binding  nucleus  transcription from RNA polymerase II promoter  nervous system development  axon guidance  cerebellum development  midbrain-hindbrain boundary morphogenesis  rhombomere 2 development  thalamus development  forebrain neuron development  cerebellar granule cell precursor proliferation  inner ear morphogenesis  positive regulation of transcription from RNA polymerase II promoter  autonomic nervous system development  
Ontology : EGO-EBIRNA polymerase II core promoter sequence-specific DNA binding  transcriptional activator activity, RNA polymerase II transcription factor binding  patterning of blood vessels  neural crest cell migration  transcription factor activity, sequence-specific DNA binding  nucleus  transcription from RNA polymerase II promoter  nervous system development  axon guidance  cerebellum development  midbrain-hindbrain boundary morphogenesis  rhombomere 2 development  thalamus development  forebrain neuron development  cerebellar granule cell precursor proliferation  inner ear morphogenesis  positive regulation of transcription from RNA polymerase II promoter  autonomic nervous system development  
NDEx Network
Atlas of Cancer Signalling NetworkGBX2
Wikipedia pathwaysGBX2
Orthology - Evolution
OrthoDB2637
GeneTree (enSembl)ENSG00000168505
Phylogenetic Trees/Animal Genes : TreeFamGBX2
Homologs : HomoloGeneGBX2
Homology/Alignments : Family Browser (UCSC)GBX2
Gene fusions - Rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerGBX2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GBX2
dbVarGBX2
ClinVarGBX2
1000_GenomesGBX2 
Exome Variant ServerGBX2
ExAC (Exome Aggregation Consortium)GBX2 (select the gene name)
Genetic variants : HAPMAP2637
Genomic Variants (DGV)GBX2 [DGVbeta]
Mutations
ICGC Data PortalGBX2 
TCGA Data PortalGBX2 
Broad Tumor PortalGBX2
OASIS PortalGBX2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGBX2 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GBX2
DgiDB (Drug Gene Interaction Database)GBX2
DoCM (Curated mutations)GBX2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GBX2 (select a term)
intoGenGBX2
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)2:237073879-237076652  ENSG00000168505
CONAN: Copy Number AnalysisGBX2 
Mutations and Diseases : HGMDGBX2
OMIM601135   
MedgenGBX2
Genetic Testing Registry GBX2
NextProtP52951 [Medical]
TSGene2637
GENETestsGBX2
Huge Navigator GBX2 [HugePedia]
snp3D : Map Gene to Disease2637
BioCentury BCIQGBX2
ClinGenGBX2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2637
Chemical/Pharm GKB GenePA28600
Clinical trialGBX2
Miscellaneous
canSAR (ICR)GBX2 (select the gene name)
Probes
Litterature
PubMed13 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGBX2
EVEXGBX2
GoPubMedGBX2
iHOPGBX2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 9 19:02:59 CEST 2016

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