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GBX2 (gastrulation brain homeobox 2)

Identity

Other names-
HGNC (Hugo) GBX2
LocusID (NCBI) 2637
Atlas_Id 40693
Location 2q37.2
Location_base_pair Starts at 237073879 and ends at 237076652 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)GBX2   4186
Cards
Entrez_Gene (NCBI)GBX2  2637  gastrulation brain homeobox 2
GeneCards (Weizmann)GBX2
Ensembl hg19 (Hinxton)ENSG00000168505 [Gene_View]  chr2:237073879-237076652 [Contig_View]  GBX2 [Vega]
Ensembl hg38 (Hinxton)ENSG00000168505 [Gene_View]  chr2:237073879-237076652 [Contig_View]  GBX2 [Vega]
ICGC DataPortalENSG00000168505
TCGA cBioPortalGBX2
AceView (NCBI)GBX2
Genatlas (Paris)GBX2
WikiGenes2637
SOURCE (Princeton)GBX2
Genomic and cartography
GoldenPath hg19 (UCSC)GBX2  -     chr2:237073879-237076652 -  2q37.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)GBX2  -     2q37.2   [Description]    (hg38-Dec_2013)
EnsemblGBX2 - 2q37.2 [CytoView hg19]  GBX2 - 2q37.2 [CytoView hg38]
Mapping of homologs : NCBIGBX2 [Mapview hg19]  GBX2 [Mapview hg38]
OMIM601135   
Gene and transcription
Genbank (Entrez)AA176205 AF118452 AK311262 BC137448 BC137449
RefSeq transcript (Entrez)NM_001301687 NM_001485
RefSeq genomic (Entrez)NC_000002 NC_018913 NT_005403 NW_004929306
Consensus coding sequences : CCDS (NCBI)GBX2
Cluster EST : UnigeneHs.735751 [ NCBI ]
CGAP (NCI)Hs.735751
Alternative Splicing : Fast-db (Paris)GSHG0018433
Alternative Splicing GalleryENSG00000168505
Gene ExpressionGBX2 [ NCBI-GEO ]     GBX2 [ SEEK ]   GBX2 [ MEM ]
SOURCE (Princeton)Expression in : [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP52951 (Uniprot)
NextProtP52951  [Medical]
With graphics : InterProP52951
Splice isoforms : SwissVarP52951 (Swissvar)
Domaine pattern : Prosite (Expaxy)HOMEOBOX_1 (PS00027)    HOMEOBOX_2 (PS50071)   
Domains : Interpro (EBI)Homeobox_CS    Homeobox_dom    Homeobox_metazoa    Homeodomain-like   
Related proteins : CluSTrP52951
Domain families : Pfam (Sanger)Homeobox (PF00046)   
Domain families : Pfam (NCBI)pfam00046   
Domain families : Smart (EMBL)HOX (SM00389)  
DMDM Disease mutations2637
Blocks (Seattle)P52951
Human Protein AtlasENSG00000168505
Peptide AtlasP52951
HPRD03087
IPIIPI00006053   IPI01020826   
Protein Interaction databases
DIP (DOE-UCLA)P52951
IntAct (EBI)P52951
FunCoupENSG00000168505
BioGRIDGBX2
IntegromeDBGBX2
STRING (EMBL)GBX2
Ontologies - Pathways
QuickGOP52951
Ontology : AmiGOpatterning of blood vessels  neural crest cell migration  sequence-specific DNA binding transcription factor activity  nucleus  transcription, DNA-templated  regulation of transcription, DNA-templated  nervous system development  axon guidance  cerebellum development  midbrain-hindbrain boundary morphogenesis  rhombomere 2 development  thalamus development  forebrain neuron development  cerebellar granule cell precursor proliferation  inner ear morphogenesis  sequence-specific DNA binding  autonomic nervous system development  
Ontology : EGO-EBIpatterning of blood vessels  neural crest cell migration  sequence-specific DNA binding transcription factor activity  nucleus  transcription, DNA-templated  regulation of transcription, DNA-templated  nervous system development  axon guidance  cerebellum development  midbrain-hindbrain boundary morphogenesis  rhombomere 2 development  thalamus development  forebrain neuron development  cerebellar granule cell precursor proliferation  inner ear morphogenesis  sequence-specific DNA binding  autonomic nervous system development  
Protein Interaction DatabaseGBX2
DoCM (Curated mutations)GBX2
Wikipedia pathwaysGBX2
Gene fusion - Rearrangements
Gene fusion: TCGA
Polymorphisms : SNP, variants
NCBI Variation ViewerGBX2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GBX2
dbVarGBX2
ClinVarGBX2
1000_GenomesGBX2 
Exome Variant ServerGBX2
SNP (GeneSNP Utah)GBX2
SNP : HGBaseGBX2
Genetic variants : HAPMAPGBX2
Genomic Variants (DGV)GBX2 [DGVbeta]
Mutations
ICGC Data PortalGBX2 
TCGA Data PortalGBX2 
Tumor PortalGBX2
Somatic Mutations in Cancer : COSMICGBX2 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)2:237073879-237076652
CONAN: Copy Number AnalysisGBX2 
Mutations and Diseases : HGMDGBX2
OMIM601135   
MedgenGBX2
NextProtP52951 [Medical]
GENETestsGBX2
Disease Genetic AssociationGBX2
Huge Navigator GBX2 [HugePedia]  GBX2 [HugeCancerGEM]
snp3D : Map Gene to Disease2637
DGIdb (Drug Gene Interaction db)GBX2
General knowledge
Homologs : HomoloGeneGBX2
Homology/Alignments : Family Browser (UCSC)GBX2
Phylogenetic Trees/Animal Genes : TreeFamGBX2
Chemical/Protein Interactions : CTD2637
Chemical/Pharm GKB GenePA28600
Clinical trialGBX2
Cancer Resource (Charite)ENSG00000168505
Other databases
Probes
Litterature
PubMed12 Pubmed reference(s) in Entrez
CoreMineGBX2
GoPubMedGBX2
iHOPGBX2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated02-2015Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 20 19:19:44 CEST 2015

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