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GC (GC vitamin D binding protein)

Identity

Alias (NCBI)DBP
DBP-maf
DBP/GC
GRD3
Gc-MAF
GcMAF
HEL-S-51
VDB
VDBG
VDBP
HGNC (Hugo) GC
HGNC Alias symbDBP
VDBP
hDBP
HGNC Previous namegroup-specific component (vitamin D binding protein)
 GC, vitamin D binding protein
LocusID (NCBI) 2638
Atlas_Id 45713
Location 4q13.3  [Link to chromosome band 4q13]
Location_base_pair Starts at 71741694 and ends at 71804041 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
GC (4q13.3) / GC (4q13.3)HOXC8 (12q13.13) / GC (4q13.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)GC   4187
Cards
Entrez_Gene (NCBI)GC    GC vitamin D binding protein
AliasesDBP; DBP-maf; DBP/GC; GRD3; 
Gc-MAF; GcMAF; HEL-S-51; VDB; VDBG; VDBP
GeneCards (Weizmann)GC
Ensembl hg19 (Hinxton)ENSG00000145321 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000145321 [Gene_View]  ENSG00000145321 [Sequence]  chr4:71741694-71804041 [Contig_View]  GC [Vega]
ICGC DataPortalENSG00000145321
TCGA cBioPortalGC
AceView (NCBI)GC
Genatlas (Paris)GC
SOURCE (Princeton)GC
Genetics Home Reference (NIH)GC
Genomic and cartography
GoldenPath hg38 (UCSC)GC  -     chr4:71741694-71804041 -  4q13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GC  -     4q13.3   [Description]    (hg19-Feb_2009)
GoldenPathGC - 4q13.3 [CytoView hg19]  GC - 4q13.3 [CytoView hg38]
ImmunoBaseENSG00000145321
Genome Data Viewer NCBIGC [Mapview hg19]  
OMIM139200   
Gene and transcription
Genbank (Entrez)AA702473 AK223458 AK290827 AK298433 AK309595
RefSeq transcript (Entrez)NM_000583 NM_001204306 NM_001204307
Consensus coding sequences : CCDS (NCBI)GC
Gene ExpressionGC [ NCBI-GEO ]   GC [ EBI - ARRAY_EXPRESS ]   GC [ SEEK ]   GC [ MEM ]
Gene Expression Viewer (FireBrowse)GC [ Firebrowse - Broad ]
GenevisibleExpression of GC in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2638
GTEX Portal (Tissue expression)GC
Human Protein AtlasENSG00000145321-GC [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP02774   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP02774  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP02774
PhosPhoSitePlusP02774
Domaine pattern : Prosite (Expaxy)ALBUMIN_1 (PS00212)    ALBUMIN_2 (PS51438)   
Domains : Interpro (EBI)ALB/AFP/VDB    Serum_albumin-like    Serum_albumin_CS    Serum_albumin_N    VitD-bd    VitD-bind_III   
Domain families : Pfam (Sanger)Serum_albumin (PF00273)    VitD-bind_III (PF09164)   
Domain families : Pfam (NCBI)pfam00273    pfam09164   
Domain families : Smart (EMBL)ALBUMIN (SM00103)  
Conserved Domain (NCBI)GC
PDB (RSDB)1J78    1J7E    1KW2    1KXP    1LOT    1MA9   
PDB Europe1J78    1J7E    1KW2    1KXP    1LOT    1MA9   
PDB (PDBSum)1J78    1J7E    1KW2    1KXP    1LOT    1MA9   
PDB (IMB)1J78    1J7E    1KW2    1KXP    1LOT    1MA9   
Structural Biology KnowledgeBase1J78    1J7E    1KW2    1KXP    1LOT    1MA9   
SCOP (Structural Classification of Proteins)1J78    1J7E    1KW2    1KXP    1LOT    1MA9   
CATH (Classification of proteins structures)1J78    1J7E    1KW2    1KXP    1LOT    1MA9   
SuperfamilyP02774
AlphaFold pdb e-kbP02774   
Human Protein Atlas [tissue]ENSG00000145321-GC [tissue]
HPRD00749
Protein Interaction databases
DIP (DOE-UCLA)P02774
IntAct (EBI)P02774
BioGRIDGC
STRING (EMBL)GC
ZODIACGC
Ontologies - Pathways
QuickGOP02774
Ontology : AmiGOactin binding  vitamin D binding  extracellular region  extracellular region  extracellular space  cytoplasm  cytosol  transport  vitamin transmembrane transport  vitamin D metabolic process  lysosomal lumen  vitamin transport  extracellular exosome  blood microparticle  vitamin transmembrane transporter activity  calcidiol binding  
Ontology : EGO-EBIactin binding  vitamin D binding  extracellular region  extracellular region  extracellular space  cytoplasm  cytosol  transport  vitamin transmembrane transport  vitamin D metabolic process  lysosomal lumen  vitamin transport  extracellular exosome  blood microparticle  vitamin transmembrane transporter activity  calcidiol binding  
NDEx NetworkGC
Atlas of Cancer Signalling NetworkGC
Wikipedia pathwaysGC
Orthology - Evolution
OrthoDB2638
GeneTree (enSembl)ENSG00000145321
Phylogenetic Trees/Animal Genes : TreeFamGC
Homologs : HomoloGeneGC
Homology/Alignments : Family Browser (UCSC)GC
Gene fusions - Rearrangements
Fusion Cancer (Beijing)HOXC8 [12q13.13]  -  GC [4q13.3]  [FUSC002283]
Fusion : QuiverGC
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGC [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GC
dbVarGC
ClinVarGC
MonarchGC
1000_GenomesGC 
Exome Variant ServerGC
GNOMAD BrowserENSG00000145321
Varsome BrowserGC
ACMGGC variants
VarityP02774
Genomic Variants (DGV)GC [DGVbeta]
DECIPHERGC [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGC 
Mutations
ICGC Data PortalGC 
TCGA Data PortalGC 
Broad Tumor PortalGC
OASIS PortalGC [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGC  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DGC
Mutations and Diseases : HGMDGC
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaGC
DgiDB (Drug Gene Interaction Database)GC
DoCM (Curated mutations)GC
CIViC (Clinical Interpretations of Variants in Cancer)GC
Cancer3DGC
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM139200   
Orphanet
DisGeNETGC
MedgenGC
Genetic Testing Registry GC
NextProtP02774 [Medical]
GENETestsGC
Target ValidationGC
Huge Navigator GC [HugePedia]
ClinGenGC
Clinical trials, drugs, therapy
MyCancerGenomeGC
Protein Interactions : CTDGC
Pharm GKB GenePA28601
PharosP02774
Clinical trialGC
Miscellaneous
canSAR (ICR)GC
HarmonizomeGC
DataMed IndexGC
Probes
Litterature
PubMed339 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXGC
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:10:29 CEST 2021

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