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GCAT (glycine C-acetyltransferase)

Identity

Alias_namesglycine C-acetyltransferase (2-amino-3-ketobutyrate coenzyme A ligase)
Alias_symbol (synonym)KBL
Other alias
HGNC (Hugo) GCAT
LocusID (NCBI) 23464
Atlas_Id 45940
Location 22q13.1  [Link to chromosome band 22q13]
Location_base_pair Starts at 37807905 and ends at 37817176 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
GCAT (22q13.1) / EML2 (19q13.32)GCAT (22q13.1) / GGA1 (22q13.1)TBC1D22A (22q13.31) / GCAT (22q13.1)
TBC1D22A 22q13.31 / GCAT 22q13.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GCAT   4188
Cards
Entrez_Gene (NCBI)GCAT  23464  glycine C-acetyltransferase
AliasesKBL
GeneCards (Weizmann)GCAT
Ensembl hg19 (Hinxton)ENSG00000100116 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000100116 [Gene_View]  chr22:37807905-37817176 [Contig_View]  GCAT [Vega]
ICGC DataPortalENSG00000100116
TCGA cBioPortalGCAT
AceView (NCBI)GCAT
Genatlas (Paris)GCAT
WikiGenes23464
SOURCE (Princeton)GCAT
Genetics Home Reference (NIH)GCAT
Genomic and cartography
GoldenPath hg38 (UCSC)GCAT  -     chr22:37807905-37817176 +  22q13.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GCAT  -     22q13.1   [Description]    (hg19-Feb_2009)
EnsemblGCAT - 22q13.1 [CytoView hg19]  GCAT - 22q13.1 [CytoView hg38]
Mapping of homologs : NCBIGCAT [Mapview hg19]  GCAT [Mapview hg38]
OMIM607422   
Gene and transcription
Genbank (Entrez)AF077740 AK123190 AK290093 BC014457 BP309052
RefSeq transcript (Entrez)NM_001171690 NM_014291
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GCAT
Cluster EST : UnigeneHs.54609 [ NCBI ]
CGAP (NCI)Hs.54609
Alternative Splicing GalleryENSG00000100116
Gene ExpressionGCAT [ NCBI-GEO ]   GCAT [ EBI - ARRAY_EXPRESS ]   GCAT [ SEEK ]   GCAT [ MEM ]
Gene Expression Viewer (FireBrowse)GCAT [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23464
GTEX Portal (Tissue expression)GCAT
Protein : pattern, domain, 3D structure
UniProt/SwissProtO75600   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO75600  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO75600
Splice isoforms : SwissVarO75600
Catalytic activity : Enzyme2.3.1.29 [ Enzyme-Expasy ]   2.3.1.292.3.1.29 [ IntEnz-EBI ]   2.3.1.29 [ BRENDA ]   2.3.1.29 [ KEGG ]   
PhosPhoSitePlusO75600
Domaine pattern : Prosite (Expaxy)AA_TRANSFER_CLASS_2 (PS00599)   
Domains : Interpro (EBI)2am3keto_CoA_ligase    Aminotrans_II_pyridoxalP_BS    Aminotransferase_I/II    PyrdxlP-dep_Trfase    PyrdxlP-dep_Trfase_major_sub1    PyrdxlP-dep_Trfase_major_sub2   
Domain families : Pfam (Sanger)Aminotran_1_2 (PF00155)   
Domain families : Pfam (NCBI)pfam00155   
Conserved Domain (NCBI)GCAT
DMDM Disease mutations23464
Blocks (Seattle)GCAT
SuperfamilyO75600
Human Protein AtlasENSG00000100116
Peptide AtlasO75600
HPRD07602
IPIIPI00026492   IPI00446745   IPI00879060   IPI00878588   IPI00879212   
Protein Interaction databases
DIP (DOE-UCLA)O75600
IntAct (EBI)O75600
FunCoupENSG00000100116
BioGRIDGCAT
STRING (EMBL)GCAT
ZODIACGCAT
Ontologies - Pathways
QuickGOO75600
Ontology : AmiGOnucleoplasm  mitochondrion  mitochondrial inner membrane  cellular amino acid metabolic process  glycine C-acetyltransferase activity  biosynthetic process  nuclear speck  L-threonine catabolic process to glycine  L-threonine catabolic process to glycine  pyridoxal phosphate binding  
Ontology : EGO-EBInucleoplasm  mitochondrion  mitochondrial inner membrane  cellular amino acid metabolic process  glycine C-acetyltransferase activity  biosynthetic process  nuclear speck  L-threonine catabolic process to glycine  L-threonine catabolic process to glycine  pyridoxal phosphate binding  
Pathways : KEGGGlycine, serine and threonine metabolism   
NDEx NetworkGCAT
Atlas of Cancer Signalling NetworkGCAT
Wikipedia pathwaysGCAT
Orthology - Evolution
OrthoDB23464
GeneTree (enSembl)ENSG00000100116
Phylogenetic Trees/Animal Genes : TreeFamGCAT
HOVERGENO75600
HOGENOMO75600
Homologs : HomoloGeneGCAT
Homology/Alignments : Family Browser (UCSC)GCAT
Gene fusions - Rearrangements
Fusion : MitelmanTBC1D22A/GCAT [22q13.31/22q13.1]  [t(22;22)(q13;q13)]  
Fusion: TCGATBC1D22A 22q13.31 GCAT 22q13.1 HNSC
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGCAT [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GCAT
dbVarGCAT
ClinVarGCAT
1000_GenomesGCAT 
Exome Variant ServerGCAT
ExAC (Exome Aggregation Consortium)GCAT (select the gene name)
Genetic variants : HAPMAP23464
Genomic Variants (DGV)GCAT [DGVbeta]
DECIPHERGCAT [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGCAT 
Mutations
ICGC Data PortalGCAT 
TCGA Data PortalGCAT 
Broad Tumor PortalGCAT
OASIS PortalGCAT [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGCAT  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGCAT
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch GCAT
DgiDB (Drug Gene Interaction Database)GCAT
DoCM (Curated mutations)GCAT (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GCAT (select a term)
intoGenGCAT
Cancer3DGCAT(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607422   
Orphanet
MedgenGCAT
Genetic Testing Registry GCAT
NextProtO75600 [Medical]
TSGene23464
GENETestsGCAT
Target ValidationGCAT
Huge Navigator GCAT [HugePedia]
snp3D : Map Gene to Disease23464
BioCentury BCIQGCAT
ClinGenGCAT
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD23464
Chemical/Pharm GKB GenePA28603
Clinical trialGCAT
Miscellaneous
canSAR (ICR)GCAT (select the gene name)
Probes
Litterature
PubMed14 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGCAT
EVEXGCAT
GoPubMedGCAT
iHOPGCAT
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:34:57 CEST 2017

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