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GCM1 (glial cells missing homolog 1)

Identity

Alias_namesGCMA
glial cells missing (Drosophila) homolog a
glial cells missing homolog 1 (Drosophila)
Alias_symbol (synonym)hGCMa
Other alias
HGNC (Hugo) GCM1
LocusID (NCBI) 8521
Atlas_Id 52694
Location 6p12.1  [Link to chromosome band 6p12]
Location_base_pair Starts at 53126962 and ends at 53148826 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GCM1   4197
Cards
Entrez_Gene (NCBI)GCM1  8521  glial cells missing homolog 1
AliasesGCMA; hGCMa
GeneCards (Weizmann)GCM1
Ensembl hg19 (Hinxton)ENSG00000137270 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000137270 [Gene_View]  ENSG00000137270 [Sequence]  chr6:53126962-53148826 [Contig_View]  GCM1 [Vega]
ICGC DataPortalENSG00000137270
TCGA cBioPortalGCM1
AceView (NCBI)GCM1
Genatlas (Paris)GCM1
WikiGenes8521
SOURCE (Princeton)GCM1
Genetics Home Reference (NIH)GCM1
Genomic and cartography
GoldenPath hg38 (UCSC)GCM1  -     chr6:53126962-53148826 -  6p12.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GCM1  -     6p12.1   [Description]    (hg19-Feb_2009)
EnsemblGCM1 - 6p12.1 [CytoView hg19]  GCM1 - 6p12.1 [CytoView hg38]
Mapping of homologs : NCBIGCM1 [Mapview hg19]  GCM1 [Mapview hg38]
OMIM603715   
Gene and transcription
Genbank (Entrez)AB026493 AB041714 AF075013 AI219562 AK309881
RefSeq transcript (Entrez)NM_003643
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GCM1
Cluster EST : UnigeneHs.28346 [ NCBI ]
CGAP (NCI)Hs.28346
Alternative Splicing GalleryENSG00000137270
Gene ExpressionGCM1 [ NCBI-GEO ]   GCM1 [ EBI - ARRAY_EXPRESS ]   GCM1 [ SEEK ]   GCM1 [ MEM ]
Gene Expression Viewer (FireBrowse)GCM1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8521
GTEX Portal (Tissue expression)GCM1
Human Protein AtlasENSG00000137270-GCM1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NP62   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NP62  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NP62
Splice isoforms : SwissVarQ9NP62
PhosPhoSitePlusQ9NP62
Domaine pattern : Prosite (Expaxy)GCM (PS50807)   
Domains : Interpro (EBI)GCM_dom_sf    Tscrpt_reg_GCM   
Domain families : Pfam (Sanger)GCM (PF03615)   
Domain families : Pfam (NCBI)pfam03615   
Domain structure : Prodom (Prabi Lyon)GCM_motif (PD014393)   
Conserved Domain (NCBI)GCM1
DMDM Disease mutations8521
Blocks (Seattle)GCM1
SuperfamilyQ9NP62
Human Protein Atlas [tissue]ENSG00000137270-GCM1 [tissue]
Peptide AtlasQ9NP62
HPRD04757
IPIIPI00413627   
Protein Interaction databases
DIP (DOE-UCLA)Q9NP62
IntAct (EBI)Q9NP62
FunCoupENSG00000137270
BioGRIDGCM1
STRING (EMBL)GCM1
ZODIACGCM1
Ontologies - Pathways
QuickGOQ9NP62
Ontology : AmiGORNA polymerase II proximal promoter sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  proximal promoter DNA-binding transcription activator activity, RNA polymerase II-specific  proximal promoter DNA-binding transcription activator activity, RNA polymerase II-specific  DNA binding  DNA-binding transcription factor activity  protein binding  nucleus  nucleus  transcription factor complex  regulation of transcription, DNA-templated  transcription by RNA polymerase II  transcription factor binding  zinc ion binding  anatomical structure morphogenesis  histone deacetylase binding  positive regulation of transcription by RNA polymerase II  astrocyte fate commitment  positive regulation of syncytium formation by plasma membrane fusion  branching involved in labyrinthine layer morphogenesis  cell differentiation involved in embryonic placenta development  regulation of cell differentiation involved in embryonic placenta development  
Ontology : EGO-EBIRNA polymerase II proximal promoter sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  proximal promoter DNA-binding transcription activator activity, RNA polymerase II-specific  proximal promoter DNA-binding transcription activator activity, RNA polymerase II-specific  DNA binding  DNA-binding transcription factor activity  protein binding  nucleus  nucleus  transcription factor complex  regulation of transcription, DNA-templated  transcription by RNA polymerase II  transcription factor binding  zinc ion binding  anatomical structure morphogenesis  histone deacetylase binding  positive regulation of transcription by RNA polymerase II  astrocyte fate commitment  positive regulation of syncytium formation by plasma membrane fusion  branching involved in labyrinthine layer morphogenesis  cell differentiation involved in embryonic placenta development  regulation of cell differentiation involved in embryonic placenta development  
NDEx NetworkGCM1
Atlas of Cancer Signalling NetworkGCM1
Wikipedia pathwaysGCM1
Orthology - Evolution
OrthoDB8521
GeneTree (enSembl)ENSG00000137270
Phylogenetic Trees/Animal Genes : TreeFamGCM1
HOVERGENQ9NP62
HOGENOMQ9NP62
Homologs : HomoloGeneGCM1
Homology/Alignments : Family Browser (UCSC)GCM1
Gene fusions - Rearrangements
Fusion : QuiverGCM1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGCM1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GCM1
dbVarGCM1
ClinVarGCM1
1000_GenomesGCM1 
Exome Variant ServerGCM1
ExAC (Exome Aggregation Consortium)ENSG00000137270
GNOMAD BrowserENSG00000137270
Varsome BrowserGCM1
Genetic variants : HAPMAP8521
Genomic Variants (DGV)GCM1 [DGVbeta]
DECIPHERGCM1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGCM1 
Mutations
ICGC Data PortalGCM1 
TCGA Data PortalGCM1 
Broad Tumor PortalGCM1
OASIS PortalGCM1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGCM1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGCM1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GCM1
DgiDB (Drug Gene Interaction Database)GCM1
DoCM (Curated mutations)GCM1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GCM1 (select a term)
intoGenGCM1
Cancer3DGCM1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603715   
Orphanet
DisGeNETGCM1
MedgenGCM1
Genetic Testing Registry GCM1
NextProtQ9NP62 [Medical]
TSGene8521
GENETestsGCM1
Target ValidationGCM1
Huge Navigator GCM1 [HugePedia]
snp3D : Map Gene to Disease8521
BioCentury BCIQGCM1
ClinGenGCM1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD8521
Chemical/Pharm GKB GenePA28614
Clinical trialGCM1
Miscellaneous
canSAR (ICR)GCM1 (select the gene name)
Probes
Litterature
PubMed47 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGCM1
EVEXGCM1
GoPubMedGCM1
iHOPGCM1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 6 11:08:07 CET 2018

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