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GCM2 (glial cells missing homolog 2)

Identity

Alias_namesGCMB
glial cells missing (Drosophila) homolog b
glial cells missing homolog 2 (Drosophila)
Alias_symbol (synonym)hGCMb
Other aliasHRPT4
HGNC (Hugo) GCM2
LocusID (NCBI) 9247
Atlas_Id 55471
Location 6p24.2  [Link to chromosome band 6p24]
Location_base_pair Starts at 10873223 and ends at 10881865 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GCM2   4198
Cards
Entrez_Gene (NCBI)GCM2  9247  glial cells missing homolog 2
AliasesGCMB; HRPT4; hGCMb
GeneCards (Weizmann)GCM2
Ensembl hg19 (Hinxton)ENSG00000124827 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000124827 [Gene_View]  ENSG00000124827 [Sequence]  chr6:10873223-10881865 [Contig_View]  GCM2 [Vega]
ICGC DataPortalENSG00000124827
TCGA cBioPortalGCM2
AceView (NCBI)GCM2
Genatlas (Paris)GCM2
WikiGenes9247
SOURCE (Princeton)GCM2
Genetics Home Reference (NIH)GCM2
Genomic and cartography
GoldenPath hg38 (UCSC)GCM2  -     chr6:10873223-10881865 -  6p24.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GCM2  -     6p24.2   [Description]    (hg19-Feb_2009)
EnsemblGCM2 - 6p24.2 [CytoView hg19]  GCM2 - 6p24.2 [CytoView hg38]
Mapping of homologs : NCBIGCM2 [Mapview hg19]  GCM2 [Mapview hg38]
OMIM146200   603716   617343   
Gene and transcription
Genbank (Entrez)AF079550 AF091149 AI028145 BC069603 BC117316
RefSeq transcript (Entrez)NM_004752
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GCM2
Cluster EST : UnigeneHs.227098 [ NCBI ]
CGAP (NCI)Hs.227098
Alternative Splicing GalleryENSG00000124827
Gene ExpressionGCM2 [ NCBI-GEO ]   GCM2 [ EBI - ARRAY_EXPRESS ]   GCM2 [ SEEK ]   GCM2 [ MEM ]
Gene Expression Viewer (FireBrowse)GCM2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9247
GTEX Portal (Tissue expression)GCM2
Human Protein AtlasENSG00000124827-GCM2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO75603   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO75603  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO75603
Splice isoforms : SwissVarO75603
PhosPhoSitePlusO75603
Domaine pattern : Prosite (Expaxy)GCM (PS50807)   
Domains : Interpro (EBI)GCM_dom_sf    Tscrpt_reg_GCM   
Domain families : Pfam (Sanger)GCM (PF03615)   
Domain families : Pfam (NCBI)pfam03615   
Domain structure : Prodom (Prabi Lyon)GCM_motif (PD014393)   
Conserved Domain (NCBI)GCM2
DMDM Disease mutations9247
Blocks (Seattle)GCM2
SuperfamilyO75603
Human Protein Atlas [tissue]ENSG00000124827-GCM2 [tissue]
Peptide AtlasO75603
HPRD04758
IPIIPI00006249   
Protein Interaction databases
DIP (DOE-UCLA)O75603
IntAct (EBI)O75603
FunCoupENSG00000124827
BioGRIDGCM2
STRING (EMBL)GCM2
ZODIACGCM2
Ontologies - Pathways
QuickGOO75603
Ontology : AmiGODNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  proximal promoter DNA-binding transcription activator activity, RNA polymerase II-specific  DNA binding  protein binding  nucleus  nucleus  nucleus  transcription by RNA polymerase II  cellular calcium ion homeostasis  multicellular organism development  cellular phosphate ion homeostasis  sequence-specific DNA binding  sequence-specific DNA binding  positive regulation of transcription by RNA polymerase II  metal ion binding  parathyroid gland development  
Ontology : EGO-EBIDNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  proximal promoter DNA-binding transcription activator activity, RNA polymerase II-specific  DNA binding  protein binding  nucleus  nucleus  nucleus  transcription by RNA polymerase II  cellular calcium ion homeostasis  multicellular organism development  cellular phosphate ion homeostasis  sequence-specific DNA binding  sequence-specific DNA binding  positive regulation of transcription by RNA polymerase II  metal ion binding  parathyroid gland development  
NDEx NetworkGCM2
Atlas of Cancer Signalling NetworkGCM2
Wikipedia pathwaysGCM2
Orthology - Evolution
OrthoDB9247
GeneTree (enSembl)ENSG00000124827
Phylogenetic Trees/Animal Genes : TreeFamGCM2
HOVERGENO75603
HOGENOMO75603
Homologs : HomoloGeneGCM2
Homology/Alignments : Family Browser (UCSC)GCM2
Gene fusions - Rearrangements
Fusion : QuiverGCM2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGCM2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GCM2
dbVarGCM2
ClinVarGCM2
1000_GenomesGCM2 
Exome Variant ServerGCM2
ExAC (Exome Aggregation Consortium)ENSG00000124827
GNOMAD BrowserENSG00000124827
Varsome BrowserGCM2
Genetic variants : HAPMAP9247
Genomic Variants (DGV)GCM2 [DGVbeta]
DECIPHERGCM2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGCM2 
Mutations
ICGC Data PortalGCM2 
TCGA Data PortalGCM2 
Broad Tumor PortalGCM2
OASIS PortalGCM2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGCM2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGCM2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GCM2
DgiDB (Drug Gene Interaction Database)GCM2
DoCM (Curated mutations)GCM2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GCM2 (select a term)
intoGenGCM2
Cancer3DGCM2(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM146200    603716    617343   
Orphanet2112   
DisGeNETGCM2
MedgenGCM2
Genetic Testing Registry GCM2
NextProtO75603 [Medical]
TSGene9247
GENETestsGCM2
Target ValidationGCM2
Huge Navigator GCM2 [HugePedia]
snp3D : Map Gene to Disease9247
BioCentury BCIQGCM2
ClinGenGCM2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9247
Chemical/Pharm GKB GenePA28615
Clinical trialGCM2
Miscellaneous
canSAR (ICR)GCM2 (select the gene name)
Probes
Litterature
PubMed36 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGCM2
EVEXGCM2
GoPubMedGCM2
iHOPGCM2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 6 11:08:07 CET 2018

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