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GCSH (glycine cleavage system protein H (aminomethyl carrier))

Identity

Alias_namesglycine cleavage system protein H (aminomethyl carrier)
Other aliasGCE
NKH
HGNC (Hugo) GCSH
LocusID (NCBI) 2653
Atlas_Id 63741
Location 16q23.2  [Link to chromosome band 16q23]
Location_base_pair Starts at 81115552 and ends at 81129980 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GCSH   4208
LRG (Locus Reference Genomic)LRG_541
Cards
Entrez_Gene (NCBI)GCSH  2653  glycine cleavage system protein H (aminomethyl carrier)
AliasesGCE; NKH
GeneCards (Weizmann)GCSH
Ensembl hg19 (Hinxton)ENSG00000140905 [Gene_View]  chr16:81115552-81129980 [Contig_View]  GCSH [Vega]
Ensembl hg38 (Hinxton)ENSG00000140905 [Gene_View]  chr16:81115552-81129980 [Contig_View]  GCSH [Vega]
ICGC DataPortalENSG00000140905
TCGA cBioPortalGCSH
AceView (NCBI)GCSH
Genatlas (Paris)GCSH
WikiGenes2653
SOURCE (Princeton)GCSH
Genetics Home Reference (NIH)GCSH
Genomic and cartography
GoldenPath hg19 (UCSC)GCSH  -     chr16:81115552-81129980 -  16q23.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)GCSH  -     16q23.2   [Description]    (hg38-Dec_2013)
EnsemblGCSH - 16q23.2 [CytoView hg19]  GCSH - 16q23.2 [CytoView hg38]
Mapping of homologs : NCBIGCSH [Mapview hg19]  GCSH [Mapview hg38]
OMIM238330   605899   
Gene and transcription
Genbank (Entrez)AI656660 AK311978 AV696698 AY533031 BC000790
RefSeq transcript (Entrez)NM_004483
RefSeq genomic (Entrez)NC_000016 NC_018927 NG_016427 NT_010498 NW_004929402
Consensus coding sequences : CCDS (NCBI)GCSH
Cluster EST : UnigeneHs.546256 [ NCBI ]
CGAP (NCI)Hs.546256
Alternative Splicing GalleryENSG00000140905
Gene ExpressionGCSH [ NCBI-GEO ]   GCSH [ EBI - ARRAY_EXPRESS ]   GCSH [ SEEK ]   GCSH [ MEM ]
Gene Expression Viewer (FireBrowse)GCSH [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2653
GTEX Portal (Tissue expression)GCSH
Protein : pattern, domain, 3D structure
UniProt/SwissProtP23434   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP23434  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP23434
Splice isoforms : SwissVarP23434
PhosPhoSitePlusP23434
Domaine pattern : Prosite (Expaxy)BIOTINYL_LIPOYL (PS50968)    LIPOYL (PS00189)   
Domains : Interpro (EBI)2-oxoA_DH_lipoyl-BS    GCV_H    GCV_H_sub    Single_hybrid_motif   
Domain families : Pfam (Sanger)GCV_H (PF01597)   
Domain families : Pfam (NCBI)pfam01597   
Conserved Domain (NCBI)GCSH
DMDM Disease mutations2653
Blocks (Seattle)GCSH
SuperfamilyP23434
Human Protein AtlasENSG00000140905
Peptide AtlasP23434
HPRD01998
IPIIPI00011604   
Protein Interaction databases
DIP (DOE-UCLA)P23434
IntAct (EBI)P23434
FunCoupENSG00000140905
BioGRIDGCSH
STRING (EMBL)GCSH
ZODIACGCSH
Ontologies - Pathways
QuickGOP23434
Ontology : AmiGOaminomethyltransferase activity  mitochondrion  glycine cleavage complex  glycine catabolic process  glycine decarboxylation via glycine cleavage system  enzyme binding  methylation  
Ontology : EGO-EBIaminomethyltransferase activity  mitochondrion  glycine cleavage complex  glycine catabolic process  glycine decarboxylation via glycine cleavage system  enzyme binding  methylation  
Pathways : KEGGGlyoxylate and dicarboxylate metabolism   
NDEx NetworkGCSH
Atlas of Cancer Signalling NetworkGCSH
Wikipedia pathwaysGCSH
Orthology - Evolution
OrthoDB2653
GeneTree (enSembl)ENSG00000140905
Phylogenetic Trees/Animal Genes : TreeFamGCSH
HOVERGENP23434
HOGENOMP23434
Homologs : HomoloGeneGCSH
Homology/Alignments : Family Browser (UCSC)GCSH
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGCSH [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GCSH
dbVarGCSH
ClinVarGCSH
1000_GenomesGCSH 
Exome Variant ServerGCSH
ExAC (Exome Aggregation Consortium)GCSH (select the gene name)
Genetic variants : HAPMAP2653
Genomic Variants (DGV)GCSH [DGVbeta]
DECIPHER (Syndromes)16:81115552-81129980  ENSG00000140905
CONAN: Copy Number AnalysisGCSH 
Mutations
ICGC Data PortalGCSH 
TCGA Data PortalGCSH 
Broad Tumor PortalGCSH
OASIS PortalGCSH [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGCSH  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGCSH
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch GCSH
DgiDB (Drug Gene Interaction Database)GCSH
DoCM (Curated mutations)GCSH (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GCSH (select a term)
intoGenGCSH
Cancer3DGCSH(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM238330    605899   
Orphanet20768    20766    20767   
MedgenGCSH
Genetic Testing Registry GCSH
NextProtP23434 [Medical]
TSGene2653
GENETestsGCSH
Huge Navigator GCSH [HugePedia]
snp3D : Map Gene to Disease2653
BioCentury BCIQGCSH
ClinGenGCSH
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2653
Chemical/Pharm GKB GenePA28621
Clinical trialGCSH
Miscellaneous
canSAR (ICR)GCSH (select the gene name)
Probes
Litterature
PubMed19 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGCSH
EVEXGCSH
GoPubMedGCSH
iHOPGCSH
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:05:57 CET 2017

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