GDA (guanine deaminase)

2006-10-01  

Identity

HGNC
GDA
LOCATION
9q21.13
LOCUSID
9615
ALIAS
CYPIN,GAH,GUANASE,NEDASIN
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 9615
MIM: 139260
HGNC: 4212
Ensembl: ENSG00000119125

Variants:

dbSNP: 9615
ClinVar: 9615
TCGA: ENSG00000119125
COSMIC: GDA

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000119125ENST00000238018Q9Y2T3
ENSG00000119125ENST00000358399Q9Y2T3
ENSG00000119125ENST00000358399A0A024R231
ENSG00000119125ENST00000376986Q5SZC6
ENSG00000119125ENST00000414671Q5SZC5
ENSG00000119125ENST00000436438Q5SZC3
ENSG00000119125ENST00000475764Q9Y2T3
ENSG00000119125ENST00000475764A0A024R231
ENSG00000119125ENST00000489618H0YDZ7
ENSG00000119125ENST00000545168Q9Y2T3

Expression (GTEx)

0
5
10
15
20
25
30
35
40
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Purine metabolismKEGGko00230
Purine metabolismKEGGhsa00230
Metabolic pathwaysKEGGhsa01100
MetabolismREACTOMER-HSA-1430728
Metabolism of nucleotidesREACTOMER-HSA-15869
Purine metabolismREACTOMER-HSA-73847
Purine catabolismREACTOMER-HSA-74259

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
204710302010Proteome analysis of the thalamus and cerebrospinal fluid reveals glycolysis dysfunction and potential biomarkers candidates for schizophrenia.42
169530612006A histochemical and immunohistochemical investigation of guanase and nedasin in rat and human tissues.1
169530632006Histochemical and immunohistochemical investigation of guanase and nedasin in human tissues.1

Citation

Dessen P

GDA (guanine deaminase)

Atlas Genet Cytogenet Oncol Haematol. 2006-10-01

Online version: http://atlasgeneticsoncology.org/gene/43269/gda