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GDF10 (growth differentiation factor 10)

Identity

Alias_symbol (synonym)BMP-3b
Other aliasBMP3B
HGNC (Hugo) GDF10
LocusID (NCBI) 2662
Atlas_Id 40700
Location 10q11.22  [Link to chromosome band 10q11]
Location_base_pair Starts at 48425788 and ends at 48439138 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GDF10   4215
Cards
Entrez_Gene (NCBI)GDF10  2662  growth differentiation factor 10
AliasesBMP-3b; BMP3B
GeneCards (Weizmann)GDF10
Ensembl hg19 (Hinxton)ENSG00000266524 [Gene_View]  chr10:48425788-48439138 [Contig_View]  GDF10 [Vega]
Ensembl hg38 (Hinxton)ENSG00000266524 [Gene_View]  chr10:48425788-48439138 [Contig_View]  GDF10 [Vega]
ICGC DataPortalENSG00000266524
TCGA cBioPortalGDF10
AceView (NCBI)GDF10
Genatlas (Paris)GDF10
WikiGenes2662
SOURCE (Princeton)GDF10
Genetics Home Reference (NIH)GDF10
Genomic and cartography
GoldenPath hg19 (UCSC)GDF10  -     chr10:48425788-48439138 -  10q11.22   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)GDF10  -     10q11.22   [Description]    (hg38-Dec_2013)
EnsemblGDF10 - 10q11.22 [CytoView hg19]  GDF10 - 10q11.22 [CytoView hg38]
Mapping of homologs : NCBIGDF10 [Mapview hg19]  GDF10 [Mapview hg38]
OMIM601361   
Gene and transcription
Genbank (Entrez)AA018253 AK310360 AK315322 BC028237 D49492
RefSeq transcript (Entrez)NM_004962
RefSeq genomic (Entrez)NC_000010 NC_018921 NT_030059 NW_004929375
Consensus coding sequences : CCDS (NCBI)GDF10
Cluster EST : UnigeneHs.2171 [ NCBI ]
CGAP (NCI)Hs.2171
Alternative Splicing GalleryENSG00000266524
Gene ExpressionGDF10 [ NCBI-GEO ]   GDF10 [ EBI - ARRAY_EXPRESS ]   GDF10 [ SEEK ]   GDF10 [ MEM ]
Gene Expression Viewer (FireBrowse)GDF10 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2662
GTEX Portal (Tissue expression)GDF10
Protein : pattern, domain, 3D structure
UniProt/SwissProtP55107   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP55107  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP55107
Splice isoforms : SwissVarP55107
PhosPhoSitePlusP55107
Domaine pattern : Prosite (Expaxy)TGF_BETA_1 (PS00250)    TGF_BETA_2 (PS51362)   
Domains : Interpro (EBI)BMP3/BMP3B    Cystine-knot_cytokine    TGF-b_C    TGF-beta-rel    TGFb_CS   
Domain families : Pfam (Sanger)TGF_beta (PF00019)   
Domain families : Pfam (NCBI)pfam00019   
Domain families : Smart (EMBL)TGFB (SM00204)  
Conserved Domain (NCBI)GDF10
DMDM Disease mutations2662
Blocks (Seattle)GDF10
SuperfamilyP55107
Human Protein AtlasENSG00000266524
Peptide AtlasP55107
HPRD03218
IPIIPI00023315   IPI00647410   
Protein Interaction databases
DIP (DOE-UCLA)P55107
IntAct (EBI)P55107
FunCoupENSG00000266524
BioGRIDGDF10
STRING (EMBL)GDF10
ZODIACGDF10
Ontologies - Pathways
QuickGOP55107
Ontology : AmiGOskeletal system development  osteoblast differentiation  cytokine activity  transforming growth factor beta receptor binding  extracellular space  transforming growth factor beta receptor signaling pathway  growth factor activity  positive regulation of pathway-restricted SMAD protein phosphorylation  positive regulation of pathway-restricted SMAD protein phosphorylation  BMP signaling pathway  regulation of apoptotic process  regulation of MAPK cascade  fat cell differentiation  negative regulation of osteoblast differentiation  cell development  SMAD protein signal transduction  
Ontology : EGO-EBIskeletal system development  osteoblast differentiation  cytokine activity  transforming growth factor beta receptor binding  extracellular space  transforming growth factor beta receptor signaling pathway  growth factor activity  positive regulation of pathway-restricted SMAD protein phosphorylation  positive regulation of pathway-restricted SMAD protein phosphorylation  BMP signaling pathway  regulation of apoptotic process  regulation of MAPK cascade  fat cell differentiation  negative regulation of osteoblast differentiation  cell development  SMAD protein signal transduction  
NDEx NetworkGDF10
Atlas of Cancer Signalling NetworkGDF10
Wikipedia pathwaysGDF10
Orthology - Evolution
OrthoDB2662
GeneTree (enSembl)ENSG00000266524
Phylogenetic Trees/Animal Genes : TreeFamGDF10
HOVERGENP55107
HOGENOMP55107
Homologs : HomoloGeneGDF10
Homology/Alignments : Family Browser (UCSC)GDF10
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGDF10 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GDF10
dbVarGDF10
ClinVarGDF10
1000_GenomesGDF10 
Exome Variant ServerGDF10
ExAC (Exome Aggregation Consortium)GDF10 (select the gene name)
Genetic variants : HAPMAP2662
Genomic Variants (DGV)GDF10 [DGVbeta]
DECIPHER (Syndromes)10:48425788-48439138  ENSG00000266524
CONAN: Copy Number AnalysisGDF10 
Mutations
ICGC Data PortalGDF10 
TCGA Data PortalGDF10 
Broad Tumor PortalGDF10
OASIS PortalGDF10 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGDF10  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGDF10
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GDF10
DgiDB (Drug Gene Interaction Database)GDF10
DoCM (Curated mutations)GDF10 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GDF10 (select a term)
intoGenGDF10
Cancer3DGDF10(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601361   
Orphanet
MedgenGDF10
Genetic Testing Registry GDF10
NextProtP55107 [Medical]
TSGene2662
GENETestsGDF10
Huge Navigator GDF10 [HugePedia]
snp3D : Map Gene to Disease2662
BioCentury BCIQGDF10
ClinGenGDF10
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2662
Chemical/Pharm GKB GenePA28630
Clinical trialGDF10
Miscellaneous
canSAR (ICR)GDF10 (select the gene name)
Probes
Litterature
PubMed13 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGDF10
EVEXGDF10
GoPubMedGDF10
iHOPGDF10
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 15:02:14 CEST 2017

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