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GDF3 (growth differentiation factor 3)

Identity

Other namesKFS3
MCOP7
MCOPCB6
HGNC (Hugo) GDF3
LocusID (NCBI) 9573
Location 12p13.31
Location_base_pair Starts at 7842381 and ends at 7848360 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)GDF3   4218
Cards
Entrez_Gene (NCBI)GDF3  9573  growth differentiation factor 3
GeneCards (Weizmann)GDF3
Ensembl (Hinxton)ENSG00000184344 [Gene_View]  chr12:7842381-7848360 [Contig_View]  GDF3 [Vega]
ICGC DataPortalENSG00000184344
cBioPortalGDF3
AceView (NCBI)GDF3
Genatlas (Paris)GDF3
WikiGenes9573
SOURCE (Princeton)NM_020634
Genomic and cartography
GoldenPath (UCSC)GDF3  -  12p13.31   chr12:7842381-7848360 -  12p13.31   [Description]    (hg19-Feb_2009)
EnsemblGDF3 - 12p13.31 [CytoView]
Mapping of homologs : NCBIGDF3 [Mapview]
OMIM606522   613702   613703   613704   
Gene and transcription
Genbank (Entrez)AF110641 AF263538 AY358875 BC030959 DQ892661
RefSeq transcript (Entrez)NM_020634
RefSeq genomic (Entrez)AC_000144 NC_000012 NC_018923 NG_028167 NT_009714 NW_001838051 NW_004929383
Consensus coding sequences : CCDS (NCBI)GDF3
Cluster EST : UnigeneHs.86232 [ NCBI ]
CGAP (NCI)Hs.86232
Alternative Splicing : Fast-db (Paris)GSHG0007221
Alternative Splicing GalleryENSG00000184344
Gene ExpressionGDF3 [ NCBI-GEO ]     GDF3 [ SEEK ]   GDF3 [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NR23 (Uniprot)
NextProtQ9NR23  [Medical]
With graphics : InterProQ9NR23
Splice isoforms : SwissVarQ9NR23 (Swissvar)
Domaine pattern : Prosite (Expaxy)TGF_BETA_1 (PS00250)    TGF_BETA_2 (PS51362)   
Domains : Interpro (EBI)Cystine-knot_cytokine [organisation]   Inhibin_asu [organisation]   TGF-b_C [organisation]   TGF-b_N [organisation]   TGF-beta-rel [organisation]   TGFb_CS [organisation]  
Related proteins : CluSTrQ9NR23
Domain families : Pfam (Sanger)TGF_beta (PF00019)    TGFb_propeptide (PF00688)   
Domain families : Pfam (NCBI)pfam00019    pfam00688   
Domain families : Smart (EMBL)TGFB (SM00204)  
DMDM Disease mutations9573
Blocks (Seattle)Q9NR23
Human Protein AtlasENSG00000184344 [gene] [tissue] [antibody] [cell] [cancer]
Peptide AtlasQ9NR23
HPRD05938
IPIIPI00299659   
Protein Interaction databases
DIP (DOE-UCLA)Q9NR23
IntAct (EBI)Q9NR23
FunCoupENSG00000184344
BioGRIDGDF3
InParanoidQ9NR23
Interologous Interaction database Q9NR23
IntegromeDBGDF3
STRING (EMBL)GDF3
Ontologies - Pathways
Ontology : AmiGOskeletal system development  eye development  in utero embryonic development  response to dietary excess  cytokine activity  extracellular space  cytoplasm  signal transduction  endoderm development  mesoderm development  growth factor activity  regulation of cell fate commitment  protein kinase binding  negative regulation of BMP signaling pathway  notochord development  somite rostral/caudal axis specification  growth  negative regulation of epidermal cell differentiation  formation of anatomical boundary  primitive streak formation  
Ontology : EGO-EBIskeletal system development  eye development  in utero embryonic development  response to dietary excess  cytokine activity  extracellular space  cytoplasm  signal transduction  endoderm development  mesoderm development  growth factor activity  regulation of cell fate commitment  protein kinase binding  negative regulation of BMP signaling pathway  notochord development  somite rostral/caudal axis specification  growth  negative regulation of epidermal cell differentiation  formation of anatomical boundary  primitive streak formation  
Protein Interaction DatabaseGDF3
Wikipedia pathwaysGDF3
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)GDF3
snp3D : Map Gene to Disease9573
SNP (GeneSNP Utah)GDF3
SNP : HGBaseGDF3
Genetic variants : HAPMAPGDF3
Exome VariantGDF3
1000_GenomesGDF3 
ICGC programENSG00000184344 
Somatic Mutations in Cancer : COSMICGDF3 
CONAN: Copy Number AnalysisGDF3 
Mutations and Diseases : HGMDGDF3
Mutations and Diseases : intOGenGDF3
Genomic VariantsGDF3  GDF3 [DGVbeta]
dbVarGDF3
ClinVarGDF3
Pred. of missensesPolyPhen-2  SIFT(SG)  SIFT(JCVI)  Align-GVGD  MutAssessor  Mutanalyser  
Pred. splicesGeneSplicer  Human Splicing Finder  MaxEntScan  
Diseases
OMIM606522    613702    613703    613704   
MedgenGDF3
GENETestsGDF3
Disease Genetic AssociationGDF3
Huge Navigator GDF3 [HugePedia]  GDF3 [HugeCancerGEM]
General knowledge
Homologs : HomoloGeneGDF3
Homology/Alignments : Family Browser (UCSC)GDF3
Phylogenetic Trees/Animal Genes : TreeFamGDF3
Chemical/Protein Interactions : CTD9573
Chemical/Pharm GKB GenePA28633
Clinical trialGDF3
Cancer Resource (Charite)ENSG00000184344
Other databases
Probes
Litterature
PubMed20 Pubmed reference(s) in Entrez
CoreMineGDF3
iHOPGDF3
OncoSearchGDF3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Aug 26 16:47:52 CEST 2014

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