Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

GDF6 (growth differentiation factor 6)

Identity

Other namesBMP13
CDMP2
KFM
KFS
KFS1
KFSL
LCA17
MCOP4
MCOPCB6
SCDO4
SGM1
HGNC (Hugo) GDF6
LocusID (NCBI) 392255
Location 8q22.1
Location_base_pair Starts at 97154558 and ends at 97173020 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)GDF6   4221
Cards
Entrez_Gene (NCBI)GDF6  392255  growth differentiation factor 6
GeneCards (Weizmann)GDF6
Ensembl (Hinxton)ENSG00000156466 [Gene_View]  chr8:97154558-97173020 [Contig_View]  GDF6 [Vega]
AceView (NCBI)GDF6
Genatlas (Paris)GDF6
WikiGenes392255
SOURCE (Princeton)NM_001001557
Genomic and cartography
GoldenPath (UCSC)GDF6  -  8q22.1   chr8:97154558-97173020 -  8q22.1   [Description]    (hg19-Feb_2009)
EnsemblGDF6 - 8q22.1 [CytoView]
Mapping of homologs : NCBIGDF6 [Mapview]
OMIM118100   120200   122600   601147   613094   613703   
Gene and transcription
Genbank (Entrez)AJ537424 BC043222 BC127947 BC127948 BC156445
RefSeq transcript (Entrez)NM_001001557
RefSeq genomic (Entrez)AC_000140 NC_000008 NC_018919 NG_008981 NT_008046 NW_001839136 NW_004929340
Consensus coding sequences : CCDS (NCBI)GDF6
Cluster EST : UnigeneHs.492277 [ NCBI ]
CGAP (NCI)Hs.492277
Alternative Splicing : Fast-db (Paris)GSHG0029729
Alternative Splicing GalleryENSG00000156466
Gene ExpressionGDF6 [ NCBI-GEO ]     GDF6 [ SEEK ]   GDF6 [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6KF10 (Uniprot)
NextProtQ6KF10  [Medical]
With graphics : InterProQ6KF10
Splice isoforms : SwissVarQ6KF10 (Swissvar)
Domaine pattern : Prosite (Expaxy)TGF_BETA_1 (PS00250)    TGF_BETA_2 (PS51362)   
Domains : Interpro (EBI)TGF-b_C    TGF-b_N    TGF-beta-rel    TGFb_CS   
Related proteins : CluSTrQ6KF10
Domain families : Pfam (Sanger)TGF_beta (PF00019)    TGFb_propeptide (PF00688)   
Domain families : Pfam (NCBI)pfam00019    pfam00688   
Domain families : Smart (EMBL)TGFB (SM00204)  
DMDM Disease mutations392255
Blocks (Seattle)Q6KF10
Human Protein AtlasENSG00000156466
Peptide AtlasQ6KF10
HPRD11002
IPIIPI00419815   IPI00816729   IPI00816550   
Protein Interaction databases
DIP (DOE-UCLA)Q6KF10
IntAct (EBI)Q6KF10
FunCoupENSG00000156466
BioGRIDGDF6
InParanoidQ6KF10
Interologous Interaction database Q6KF10
IntegromeDBGDF6
STRING (EMBL)GDF6
Ontologies - Pathways
Ontology : AmiGOcytokine activity  extracellular space  growth factor activity  positive regulation of pathway-restricted SMAD protein phosphorylation  BMP signaling pathway  activin receptor signaling pathway  growth  protein homodimerization activity  positive regulation of neuron differentiation  positive regulation of transcription, DNA-dependent  pathway-restricted SMAD protein phosphorylation  retinal cell apoptotic process  
Ontology : EGO-EBIcytokine activity  extracellular space  growth factor activity  positive regulation of pathway-restricted SMAD protein phosphorylation  BMP signaling pathway  activin receptor signaling pathway  growth  protein homodimerization activity  positive regulation of neuron differentiation  positive regulation of transcription, DNA-dependent  pathway-restricted SMAD protein phosphorylation  retinal cell apoptotic process  
Pathways : KEGGTGF-beta signaling pathway    Hippo signaling pathway   
REACTOMEGDF6
Protein Interaction DatabaseGDF6
Wikipedia pathwaysGDF6
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)GDF6
SNP (GeneSNP Utah)GDF6
SNP : HGBaseGDF6
Genetic variants : HAPMAPGDF6
1000_GenomesGDF6 
ICGC programENSG00000156466 
Somatic Mutations in Cancer : COSMICGDF6 
CONAN: Copy Number AnalysisGDF6 
Mutations and Diseases : HGMDGDF6
OMIM118100    120200    122600    601147    613094    613703   
GENETestsGDF6
Disease Genetic AssociationGDF6
Huge Navigator GDF6 [HugePedia]  GDF6 [HugeCancerGEM]
Genomic VariantsGDF6  GDF6 [DGVbeta]
Exome VariantGDF6
dbVarGDF6
ClinVarGDF6
snp3D : Map Gene to Disease392255
General knowledge
Homologs : HomoloGeneGDF6
Homology/Alignments : Family Browser (UCSC)GDF6
Phylogenetic Trees/Animal Genes : TreeFamGDF6
Chemical/Protein Interactions : CTD392255
Chemical/Pharm GKB GenePA28636
Clinical trialGDF6
Cancer Resource (Charite)ENSG00000156466
Other databases
Probes
Litterature
PubMed27 Pubmed reference(s) in Entrez
CoreMineGDF6
iHOPGDF6
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Apr 18 17:14:50 CEST 2014

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.