Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

GDF9 (growth differentiation factor 9)

Identity

Other alias-
HGNC (Hugo) GDF9
LocusID (NCBI) 2661
Atlas_Id 40704
Location 5q31.1  [Link to chromosome band 5q31]
Location_base_pair Starts at 132196874 and ends at 132202576 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
NCBP2 (3q29) / GDF9 (5q31.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GDF9   4224
Cards
Entrez_Gene (NCBI)GDF9  2661  growth differentiation factor 9
Aliases
GeneCards (Weizmann)GDF9
Ensembl hg19 (Hinxton)ENSG00000164404 [Gene_View]  chr5:132196874-132202576 [Contig_View]  GDF9 [Vega]
Ensembl hg38 (Hinxton)ENSG00000164404 [Gene_View]  chr5:132196874-132202576 [Contig_View]  GDF9 [Vega]
ICGC DataPortalENSG00000164404
TCGA cBioPortalGDF9
AceView (NCBI)GDF9
Genatlas (Paris)GDF9
WikiGenes2661
SOURCE (Princeton)GDF9
Genetics Home Reference (NIH)GDF9
Genomic and cartography
GoldenPath hg19 (UCSC)GDF9  -     chr5:132196874-132202576 -  5q31.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)GDF9  -     5q31.1   [Description]    (hg38-Dec_2013)
EnsemblGDF9 - 5q31.1 [CytoView hg19]  GDF9 - 5q31.1 [CytoView hg38]
Mapping of homologs : NCBIGDF9 [Mapview hg19]  GDF9 [Mapview hg38]
OMIM601918   
Gene and transcription
Genbank (Entrez)AA604716 AK301962 AK315973 BC096228 BC096229
RefSeq transcript (Entrez)NM_001288824 NM_001288825 NM_001288826 NM_001288827 NM_001288828 NM_005260
RefSeq genomic (Entrez)NC_000005 NC_018916 NT_034772 NW_004929323
Consensus coding sequences : CCDS (NCBI)GDF9
Cluster EST : UnigeneHs.742490 [ NCBI ]
CGAP (NCI)Hs.742490
Alternative Splicing GalleryENSG00000164404
Gene ExpressionGDF9 [ NCBI-GEO ]   GDF9 [ EBI - ARRAY_EXPRESS ]   GDF9 [ SEEK ]   GDF9 [ MEM ]
Gene Expression Viewer (FireBrowse)GDF9 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2661
GTEX Portal (Tissue expression)GDF9
Protein : pattern, domain, 3D structure
UniProt/SwissProtO60383   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO60383  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO60383
Splice isoforms : SwissVarO60383
PhosPhoSitePlusO60383
Domaine pattern : Prosite (Expaxy)TGF_BETA_1 (PS00250)    TGF_BETA_2 (PS51362)   
Domains : Interpro (EBI)Cystine-knot_cytokine    Growth_differentiation_fac-9    TGF-b_C    TGF-beta-rel    TGFb_CS   
Domain families : Pfam (Sanger)TGF_beta (PF00019)   
Domain families : Pfam (NCBI)pfam00019   
Domain families : Smart (EMBL)TGFB (SM00204)  
Conserved Domain (NCBI)GDF9
DMDM Disease mutations2661
Blocks (Seattle)GDF9
SuperfamilyO60383
Human Protein AtlasENSG00000164404
Peptide AtlasO60383
HPRD03560
IPIIPI00029127   
Protein Interaction databases
DIP (DOE-UCLA)O60383
IntAct (EBI)O60383
FunCoupENSG00000164404
BioGRIDGDF9
STRING (EMBL)GDF9
ZODIACGDF9
Ontologies - Pathways
QuickGOO60383
Ontology : AmiGOoocyte growth  cytokine activity  transforming growth factor beta receptor binding  extracellular space  cytoplasm  transforming growth factor beta receptor signaling pathway  female gamete generation  growth factor activity  positive regulation of cell proliferation  positive regulation of pathway-restricted SMAD protein phosphorylation  negative regulation of cell growth  BMP signaling pathway  regulation of apoptotic process  regulation of MAPK cascade  cell development  SMAD protein signal transduction  regulation of progesterone secretion  regulation of progesterone secretion  
Ontology : EGO-EBIoocyte growth  cytokine activity  transforming growth factor beta receptor binding  extracellular space  cytoplasm  transforming growth factor beta receptor signaling pathway  female gamete generation  growth factor activity  positive regulation of cell proliferation  positive regulation of pathway-restricted SMAD protein phosphorylation  negative regulation of cell growth  BMP signaling pathway  regulation of apoptotic process  regulation of MAPK cascade  cell development  SMAD protein signal transduction  regulation of progesterone secretion  regulation of progesterone secretion  
Pathways : KEGGOvarian steroidogenesis   
NDEx NetworkGDF9
Atlas of Cancer Signalling NetworkGDF9
Wikipedia pathwaysGDF9
Orthology - Evolution
OrthoDB2661
GeneTree (enSembl)ENSG00000164404
Phylogenetic Trees/Animal Genes : TreeFamGDF9
HOVERGENO60383
HOGENOMO60383
Homologs : HomoloGeneGDF9
Homology/Alignments : Family Browser (UCSC)GDF9
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGDF9 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GDF9
dbVarGDF9
ClinVarGDF9
1000_GenomesGDF9 
Exome Variant ServerGDF9
ExAC (Exome Aggregation Consortium)GDF9 (select the gene name)
Genetic variants : HAPMAP2661
Genomic Variants (DGV)GDF9 [DGVbeta]
DECIPHER (Syndromes)5:132196874-132202576  ENSG00000164404
CONAN: Copy Number AnalysisGDF9 
Mutations
ICGC Data PortalGDF9 
TCGA Data PortalGDF9 
Broad Tumor PortalGDF9
OASIS PortalGDF9 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGDF9  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGDF9
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GDF9
DgiDB (Drug Gene Interaction Database)GDF9
DoCM (Curated mutations)GDF9 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GDF9 (select a term)
intoGenGDF9
Cancer3DGDF9(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601918   
Orphanet
MedgenGDF9
Genetic Testing Registry GDF9
NextProtO60383 [Medical]
TSGene2661
GENETestsGDF9
Huge Navigator GDF9 [HugePedia]
snp3D : Map Gene to Disease2661
BioCentury BCIQGDF9
ClinGenGDF9
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2661
Chemical/Pharm GKB GenePA28639
Clinical trialGDF9
Miscellaneous
canSAR (ICR)GDF9 (select the gene name)
Probes
Litterature
PubMed85 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGDF9
EVEXGDF9
GoPubMedGDF9
iHOPGDF9
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Mar 14 13:07:17 CET 2017

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.