Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

GDI1 (GDP dissociation inhibitor 1)

Identity

Alias_namesMRX48
MRX41
GDIL
Alias_symbol (synonym)RABGDIA
XAP-4
OPHN2
FLJ41411
Other alias1A
RABGD1A
HGNC (Hugo) GDI1
LocusID (NCBI) 2664
Atlas_Id 45753
Location Xq28  [Link to chromosome band Xq28]
Location_base_pair Starts at 154436913 and ends at 154443467 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CHD3 (17p13.1) / GDI1 (Xq28)CPE (4q32.3) / GDI1 (Xq28)GDI1 (Xq28) / GDI1 (Xq28)
GDI1 (Xq28) / TMEM181 (6q25.3)LOC100507412 (-) / GDI1 (Xq28)SNHG1 (11q12.3) / GDI1 (Xq28)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GDI1   4226
Cards
Entrez_Gene (NCBI)GDI1  2664  GDP dissociation inhibitor 1
Aliases1A; GDIL; MRX41; MRX48; 
OPHN2; RABGD1A; RABGDIA; XAP-4
GeneCards (Weizmann)GDI1
Ensembl hg19 (Hinxton)ENSG00000203879 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000203879 [Gene_View]  chrX:154436913-154443467 [Contig_View]  GDI1 [Vega]
ICGC DataPortalENSG00000203879
TCGA cBioPortalGDI1
AceView (NCBI)GDI1
Genatlas (Paris)GDI1
WikiGenes2664
SOURCE (Princeton)GDI1
Genetics Home Reference (NIH)GDI1
Genomic and cartography
GoldenPath hg38 (UCSC)GDI1  -     chrX:154436913-154443467 +  Xq28   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GDI1  -     Xq28   [Description]    (hg19-Feb_2009)
EnsemblGDI1 - Xq28 [CytoView hg19]  GDI1 - Xq28 [CytoView hg38]
Mapping of homologs : NCBIGDI1 [Mapview hg19]  GDI1 [Mapview hg38]
OMIM300104   300849   
Gene and transcription
Genbank (Entrez)###############################################################################################################################################################################################################################################################
RefSeq transcript (Entrez)NM_001493
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GDI1
Cluster EST : UnigeneHs.595950 [ NCBI ]
CGAP (NCI)Hs.595950
Alternative Splicing GalleryENSG00000203879
Gene ExpressionGDI1 [ NCBI-GEO ]   GDI1 [ EBI - ARRAY_EXPRESS ]   GDI1 [ SEEK ]   GDI1 [ MEM ]
Gene Expression Viewer (FireBrowse)GDI1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2664
GTEX Portal (Tissue expression)GDI1
Protein : pattern, domain, 3D structure
UniProt/SwissProtP31150   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP31150  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP31150
Splice isoforms : SwissVarP31150
PhosPhoSitePlusP31150
Domains : Interpro (EBI)FAD/NAD-binding_dom    GDP_dissociation_inhibitor    RabGDI   
Domain families : Pfam (Sanger)GDI (PF00996)   
Domain families : Pfam (NCBI)pfam00996   
Conserved Domain (NCBI)GDI1
DMDM Disease mutations2664
Blocks (Seattle)GDI1
SuperfamilyP31150
Human Protein AtlasENSG00000203879
Peptide AtlasP31150
HPRD02114
IPIIPI00010154   IPI00910113   IPI00976038   IPI00878124   IPI00878311   IPI00878472   
Protein Interaction databases
DIP (DOE-UCLA)P31150
IntAct (EBI)P31150
FunCoupENSG00000203879
BioGRIDGDI1
STRING (EMBL)GDI1
ZODIACGDI1
Ontologies - Pathways
QuickGOP31150
Ontology : AmiGOGDP-dissociation inhibitor activity  Rab GDP-dissociation inhibitor activity  GTPase activator activity  protein binding  cytoplasm  Golgi apparatus  cytosol  signal transduction  protein transport  oxidoreductase activity  Rab GTPase binding  midbody  Rab protein signal transduction  neuron projection  myelin sheath  protein complex  positive regulation of GTPase activity  negative regulation of axonogenesis  regulation of small GTPase mediated signal transduction  response to calcium ion  oxidation-reduction process  membrane organization  negative regulation of protein targeting to membrane  
Ontology : EGO-EBIGDP-dissociation inhibitor activity  Rab GDP-dissociation inhibitor activity&njs0; GTPase activator activity  protein binding  cytoplasm  Golgi apparatus  cytosol  signal transduction  protein transport  oxidoreductase activity  Rab GTPase binding  midbody  Rab protein signal transduction  neuron projection  myelin sheath  protein complex  positive regulation of GTPase activity  negative regulation of axonogenesis  regulation of small GTPase mediated signal transduction  response to calcium ion  oxidation-reduction process  membrane organization  negative regulation of protein targeting to membrane  
NDEx NetworkGDI1
Atlas of Cancer Signalling NetworkGDI1
Wikipedia pathwaysGDI1
Orthology - Evolution
OrthoDB2664
GeneTree (enSembl)ENSG00000203879
Phylogenetic Trees/Animal Genes : TreeFamGDI1
HOVERGENP31150
HOGENOMP31150
Homologs : HomoloGeneGDI1
Homology/Alignments : Family Browser (UCSC)GDI1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGDI1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GDI1
dbVarGDI1
ClinVarGDI1
1000_GenomesGDI1 
Exome Variant ServerGDI1
ExAC (Exome Aggregation Consortium)GDI1 (select the gene name)
Genetic variants : HAPMAP2664
Genomic Variants (DGV)GDI1 [DGVbeta]
DECIPHERGDI1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGDI1 
Mutations
ICGC Data PortalGDI1 
TCGA Data PortalGDI1 
Broad Tumor PortalGDI1
OASIS PortalGDI1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGDI1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGDI1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GDI1
DgiDB (Drug Gene Interaction Database)GDI1
DoCM (Curated mutations)GDI1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GDI1 (select a term)
intoGenGDI1
Cancer3DGDI1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM300104    300849   
Orphanet3256   
MedgenGDI1
Genetic Testing Registry GDI1
NextProtP31150 [Medical]
TSGene2664
GENETestsGDI1
Target ValidationGDI1
Huge Navigator GDI1 [HugePedia]
snp3D : Map Gene to Disease2664
BioCentury BCIQGDI1
ClinGenGDI1 (curated)
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2664
Chemical/Pharm GKB GenePA28641
Clinical trialGDI1
Miscellaneous
canSAR (ICR)GDI1 (select the gene name)
Probes
Litterature
PubMed73 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGDI1
EVEXGDI1
GoPubMedGDI1
iHOPGDI1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 25 19:09:39 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.