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GDPD5 (glycerophosphodiester phosphodiesterase domain containing 5)

Identity

Alias_symbol (synonym)PP1665
GDE2
Other alias
HGNC (Hugo) GDPD5
LocusID (NCBI) 81544
Atlas_Id 53254
Location 11q13.4  [Link to chromosome band 11q13]
Location_base_pair Starts at 75434640 and ends at 75525554 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ARRB1 (11q13.4) / GDPD5 (11q13.4)CHKA (11q13.2) / GDPD5 (11q13.4)CSF1R (5q32) / GDPD5 (11q13.4)
FBXL20 (17q12) / GDPD5 (11q13.4)GDPD5 (11q13.4) / GDPD5 (11q13.4)KLHL35 (11q13.4) / GDPD5 (11q13.4)
LAMC1 (1q25.3) / GDPD5 (11q13.4)MRPL48 (11q13.4) / GDPD5 (11q13.4)ARRB1 11q13.4 / GDPD5 11q13.4
CHKA 11q13.2 / GDPD5 11q13.4MRPL48 11q13.4 / GDPD5 11q13.4

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GDPD5   28804
Cards
Entrez_Gene (NCBI)GDPD5  81544  glycerophosphodiester phosphodiesterase domain containing 5
AliasesGDE2; PP1665
GeneCards (Weizmann)GDPD5
Ensembl hg19 (Hinxton)ENSG00000158555 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000158555 [Gene_View]  chr11:75434640-75525554 [Contig_View]  GDPD5 [Vega]
ICGC DataPortalENSG00000158555
TCGA cBioPortalGDPD5
AceView (NCBI)GDPD5
Genatlas (Paris)GDPD5
WikiGenes81544
SOURCE (Princeton)GDPD5
Genetics Home Reference (NIH)GDPD5
Genomic and cartography
GoldenPath hg38 (UCSC)GDPD5  -     chr11:75434640-75525554 -  11q13.4   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GDPD5  -     11q13.4   [Description]    (hg19-Feb_2009)
EnsemblGDPD5 - 11q13.4 [CytoView hg19]  GDPD5 - 11q13.4 [CytoView hg38]
Mapping of homologs : NCBIGDPD5 [Mapview hg19]  GDPD5 [Mapview hg38]
OMIM609632   
Gene and transcription
Genbank (Entrez)AF217989 AF289614 AF318351 AF318377 AF451987
RefSeq transcript (Entrez)NM_030792
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GDPD5
Cluster EST : UnigeneHs.503297 [ NCBI ]
CGAP (NCI)Hs.503297
Alternative Splicing GalleryENSG00000158555
Gene ExpressionGDPD5 [ NCBI-GEO ]   GDPD5 [ EBI - ARRAY_EXPRESS ]   GDPD5 [ SEEK ]   GDPD5 [ MEM ]
Gene Expression Viewer (FireBrowse)GDPD5 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)81544
GTEX Portal (Tissue expression)GDPD5
Human Protein AtlasENSG00000158555-GDPD5 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8WTR4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8WTR4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8WTR4
Splice isoforms : SwissVarQ8WTR4
Catalytic activity : Enzyme3.1.-.- [ Enzyme-Expasy ]   3.1.-.-3.1.-.- [ IntEnz-EBI ]   3.1.-.- [ BRENDA ]   3.1.-.- [ KEGG ]   
PhosPhoSitePlusQ8WTR4
Domaine pattern : Prosite (Expaxy)GP_PDE (PS51704)   
Domains : Interpro (EBI)GlyceroP-diester-Pdiesterase    GP_PDE_dom    PLC-like_Pdiesterase_TIM-brl   
Domain families : Pfam (Sanger)GDPD (PF03009)   
Domain families : Pfam (NCBI)pfam03009   
Conserved Domain (NCBI)GDPD5
DMDM Disease mutations81544
Blocks (Seattle)GDPD5
SuperfamilyQ8WTR4
Human Protein Atlas [tissue]ENSG00000158555-GDPD5 [tissue]
Peptide AtlasQ8WTR4
HPRD15159
IPIIPI00302491   IPI00744331   IPI00788106   IPI00788182   IPI00786979   IPI00387102   IPI00465349   IPI00978582   IPI00980657   
Protein Interaction databases
DIP (DOE-UCLA)Q8WTR4
IntAct (EBI)Q8WTR4
FunCoupENSG00000158555
BioGRIDGDPD5
STRING (EMBL)GDPD5
ZODIACGDPD5
Ontologies - Pathways
QuickGOQ8WTR4
Ontology : AmiGOprotein binding  lipid metabolic process  glycerophosphodiester phosphodiesterase activity  integral component of membrane  spinal cord motor neuron differentiation  cerebral cortex neuron differentiation  axon  growth cone  neuron projection development  neuronal cell body  positive regulation of neuron differentiation  negative regulation of Notch signaling pathway  positive regulation of cell cycle  glycerophosphocholine phosphodiesterase activity  regulation of timing of cell differentiation  perinuclear endoplasmic reticulum  
Ontology : EGO-EBIprotein binding  lipid metabolic process  glycerophosphodiester phosphodiesterase activity  integral component of membrane  spinal cord motor neuron differentiation  cerebral cortex neuron differentiation  axon  growth cone  neuron projection development  neuronal cell body  positive regulation of neuron differentiation  negative regulation of Notch signaling pathway  positive regulation of cell cycle  glycerophosphocholine phosphodiesterase activity  regulation of timing of cell differentiation  perinuclear endoplasmic reticulum  
NDEx NetworkGDPD5
Atlas of Cancer Signalling NetworkGDPD5
Wikipedia pathwaysGDPD5
Orthology - Evolution
OrthoDB81544
GeneTree (enSembl)ENSG00000158555
Phylogenetic Trees/Animal Genes : TreeFamGDPD5
HOVERGENQ8WTR4
HOGENOMQ8WTR4
Homologs : HomoloGeneGDPD5
Homology/Alignments : Family Browser (UCSC)GDPD5
Gene fusions - Rearrangements
Fusion : MitelmanARRB1/GDPD5 [11q13.4/11q13.4]  [t(11;11)(q13;q13)]  
Fusion : MitelmanCHKA/GDPD5 [11q13.2/11q13.4]  [t(11;11)(q13;q13)]  
Fusion : MitelmanFBXL20/GDPD5 [17q12/11q13.4]  [t(11;17)(q13;q12)]  
Fusion : MitelmanMRPL48/GDPD5 [11q13.4/11q13.4]  [t(11;11)(q13;q13)]  
Fusion: TCGA_MDACCARRB1 11q13.4 GDPD5 11q13.4 BRCA LUAD
Fusion: TCGA_MDACCCHKA 11q13.2 GDPD5 11q13.4 LUAD
Fusion: TCGA_MDACCMRPL48 11q13.4 GDPD5 11q13.4 LUSC
Tumor Fusion PortalGDPD5
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGDPD5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GDPD5
dbVarGDPD5
ClinVarGDPD5
1000_GenomesGDPD5 
Exome Variant ServerGDPD5
ExAC (Exome Aggregation Consortium)ENSG00000158555
GNOMAD BrowserENSG00000158555
Genetic variants : HAPMAP81544
Genomic Variants (DGV)GDPD5 [DGVbeta]
DECIPHERGDPD5 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGDPD5 
Mutations
ICGC Data PortalGDPD5 
TCGA Data PortalGDPD5 
Broad Tumor PortalGDPD5
OASIS PortalGDPD5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGDPD5  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGDPD5
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GDPD5
DgiDB (Drug Gene Interaction Database)GDPD5
DoCM (Curated mutations)GDPD5 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GDPD5 (select a term)
intoGenGDPD5
Cancer3DGDPD5(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609632   
Orphanet
DisGeNETGDPD5
MedgenGDPD5
Genetic Testing Registry GDPD5
NextProtQ8WTR4 [Medical]
TSGene81544
GENETestsGDPD5
Target ValidationGDPD5
Huge Navigator GDPD5 [HugePedia]
snp3D : Map Gene to Disease81544
BioCentury BCIQGDPD5
ClinGenGDPD5
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD81544
Chemical/Pharm GKB GenePA142671743
Clinical trialGDPD5
Miscellaneous
canSAR (ICR)GDPD5 (select the gene name)
Probes
Litterature
PubMed13 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGDPD5
EVEXGDPD5
GoPubMedGDPD5
iHOPGDPD5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:14:27 CET 2017

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