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GEMIN2 (gem nuclear organelle associated protein 2)

Identity

Alias_namesSIP1
survival of motor neuron protein interacting protein 1
gem (nuclear organelle) associated protein 2
Other aliasSIP1-delta
HGNC (Hugo) GEMIN2
LocusID (NCBI) 8487
Atlas_Id 52343
Location 14q21.1  [Link to chromosome band 14q21]
Location_base_pair Starts at 39114284 and ends at 39136973 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CTAGE5 (14q21.1) / GEMIN2 (14q21.1)PNN (14q21.1) / GEMIN2 (14q21.1)PPP2R2A (8p21.2) / GEMIN2 (14q21.1)
PTTG1IP (21q22.3) / GEMIN2 (14q21.1)CTAGE5 GEMIN2 14q21.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GEMIN2   10884
Cards
Entrez_Gene (NCBI)GEMIN2  8487  gem nuclear organelle associated protein 2
AliasesSIP1; SIP1-delta
GeneCards (Weizmann)GEMIN2
Ensembl hg19 (Hinxton)ENSG00000092208 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000092208 [Gene_View]  chr14:39114284-39136973 [Contig_View]  GEMIN2 [Vega]
ICGC DataPortalENSG00000092208
TCGA cBioPortalGEMIN2
AceView (NCBI)GEMIN2
Genatlas (Paris)GEMIN2
WikiGenes8487
SOURCE (Princeton)GEMIN2
Genetics Home Reference (NIH)GEMIN2
Genomic and cartography
GoldenPath hg38 (UCSC)GEMIN2  -     chr14:39114284-39136973 +  14q21.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GEMIN2  -     14q21.1   [Description]    (hg19-Feb_2009)
EnsemblGEMIN2 - 14q21.1 [CytoView hg19]  GEMIN2 - 14q21.1 [CytoView hg38]
Mapping of homologs : NCBIGEMIN2 [Mapview hg19]  GEMIN2 [Mapview hg38]
OMIM602595   
Gene and transcription
Genbank (Entrez)AB037701 AB037702 AB037703 AF027150 AK313947
RefSeq transcript (Entrez)NM_001009182 NM_001009183 NM_003616
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GEMIN2
Cluster EST : UnigeneHs.652307 [ NCBI ]
CGAP (NCI)Hs.652307
Alternative Splicing GalleryENSG00000092208
Gene ExpressionGEMIN2 [ NCBI-GEO ]   GEMIN2 [ EBI - ARRAY_EXPRESS ]   GEMIN2 [ SEEK ]   GEMIN2 [ MEM ]
Gene Expression Viewer (FireBrowse)GEMIN2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8487
GTEX Portal (Tissue expression)GEMIN2
Protein : pattern, domain, 3D structure
UniProt/SwissProtO14893   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO14893  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO14893
Splice isoforms : SwissVarO14893
PhosPhoSitePlusO14893
Domains : Interpro (EBI)GEMIN2   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)GEMIN2
DMDM Disease mutations8487
Blocks (Seattle)GEMIN2
PDB (SRS)2LEH    3S6N   
PDB (PDBSum)2LEH    3S6N   
PDB (IMB)2LEH    3S6N   
PDB (RSDB)2LEH    3S6N   
Structural Biology KnowledgeBase2LEH    3S6N   
SCOP (Structural Classification of Proteins)2LEH    3S6N   
CATH (Classification of proteins structures)2LEH    3S6N   
SuperfamilyO14893
Human Protein AtlasENSG00000092208
Peptide AtlasO14893
HPRD03999
IPIIPI00024281   IPI00164779   IPI00550676   IPI00385589   IPI00984834   IPI00976839   IPI00985393   IPI00981013   
Protein Interaction databases
DIP (DOE-UCLA)O14893
IntAct (EBI)O14893
FunCoupENSG00000092208
BioGRIDGEMIN2
STRING (EMBL)GEMIN2
ZODIACGEMIN2
Ontologies - Pathways
QuickGOO14893
Ontology : AmiGOspliceosomal complex assembly  RNA splicing, via transesterification reactions  spliceosomal snRNP assembly  spliceosomal snRNP assembly  protein binding  nucleus  nucleoplasm  spliceosomal complex  nucleolus  cytosol  cytosol  mRNA processing  RNA splicing  nuclear body  SMN complex  SMN-Sm protein complex  nuclear import  Gemini of coiled bodies  
Ontology : EGO-EBIspliceosomal complex assembly  RNA splicing, via transesterification reactions  spliceosomal snRNP assembly  spliceosomal snRNP assembly  protein binding  nucleus  nucleoplasm  spliceosomal complex  nucleolus  cytosol  cytosol  mRNA processing  RNA splicing  nuclear body  SMN complex  SMN-Sm protein complex  nuclear import  Gemini of coiled bodies  
Pathways : KEGGRNA transport   
NDEx NetworkGEMIN2
Atlas of Cancer Signalling NetworkGEMIN2
Wikipedia pathwaysGEMIN2
Orthology - Evolution
OrthoDB8487
GeneTree (enSembl)ENSG00000092208
Phylogenetic Trees/Animal Genes : TreeFamGEMIN2
HOVERGENO14893
HOGENOMO14893
Homologs : HomoloGeneGEMIN2
Homology/Alignments : Family Browser (UCSC)GEMIN2
Gene fusions - Rearrangements
Fusion : MitelmanCTAGE5/GEMIN2 [14q21.1/14q21.1]  [t(14;14)(q21;q21)]  
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGEMIN2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GEMIN2
dbVarGEMIN2
ClinVarGEMIN2
1000_GenomesGEMIN2 
Exome Variant ServerGEMIN2
ExAC (Exome Aggregation Consortium)GEMIN2 (select the gene name)
Genetic variants : HAPMAP8487
Genomic Variants (DGV)GEMIN2 [DGVbeta]
DECIPHERGEMIN2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGEMIN2 
Mutations
ICGC Data PortalGEMIN2 
TCGA Data PortalGEMIN2 
Broad Tumor PortalGEMIN2
OASIS PortalGEMIN2 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDGEMIN2
BioMutasearch GEMIN2
DgiDB (Drug Gene Interaction Database)GEMIN2
DoCM (Curated mutations)GEMIN2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GEMIN2 (select a term)
intoGenGEMIN2
Cancer3DGEMIN2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602595   
Orphanet
MedgenGEMIN2
Genetic Testing Registry GEMIN2
NextProtO14893 [Medical]
TSGene8487
GENETestsGEMIN2
Target ValidationGEMIN2
Huge Navigator GEMIN2 [HugePedia]
snp3D : Map Gene to Disease8487
BioCentury BCIQGEMIN2
ClinGenGEMIN2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD8487
Chemical/Pharm GKB GenePA35784
Clinical trialGEMIN2
Miscellaneous
canSAR (ICR)GEMIN2 (select the gene name)
Probes
Litterature
PubMed71 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGEMIN2
EVEXGEMIN2
GoPubMedGEMIN2
iHOPGEMIN2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 12:35:05 CEST 2017

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