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GET1 (guided entry of tail-anchored proteins factor 1)

Identity

Alias (NCBI)CHD5
WRB
HGNC (Hugo) GET1
HGNC Alias symbCHD5
GET1
LocusID (NCBI) 7485
Atlas_Id 75768
Location 21q22.2  [Link to chromosome band 21q22]
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
WRB NLKWRB KCNJ15
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute



Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 6 ]
  t(17;21)(q11;q22) WRB/NLK
UMODL1/WRB (21q22)
WRB/KCNJ15 (21q22)
WRB/SH3BGR (21q22)
WRB/SH3BGR (21q22)
WRB/SH3BGR (21q22)


External links

Nomenclature
HGNC (Hugo)GET1   12790
LRG (Locus Reference Genomic)LRG_1060
Cards
Entrez_Gene (NCBI)GET1  7485  guided entry of tail-anchored proteins factor 1
AliasesCHD5; WRB
GeneCards (Weizmann)GET1
Ensembl hg19 (Hinxton)ENSG00000182093 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000182093 [Gene_View]  ENSG00000182093 [Sequence]  - [Contig_View]  GET1 [Vega]
ICGC DataPortalENSG00000182093
TCGA cBioPortalGET1
AceView (NCBI)GET1
Genatlas (Paris)GET1
WikiGenes7485
SOURCE (Princeton)GET1
Genetics Home Reference (NIH)GET1
Genomic and cartography
GoldenPath hg38 (UCSC)GET1  -  
GoldenPath hg19 (UCSC)GET1  -  
GoldenPathGET1 - [CytoView hg19]  GET1 - [CytoView hg38]
ImmunoBaseENSG00000182093
genome Data Viewer NCBIGET1 [Mapview hg19]  
OMIM602915   
Gene and transcription
Genbank (Entrez)AK293113 AK293866 AK297186 AK299144 AK299245
RefSeq transcript (Entrez)NM_001146218 NM_001350293 NM_001350294 NM_001350295 NM_001350296 NM_004627
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GET1
Alternative Splicing GalleryENSG00000182093
Gene ExpressionGET1 [ NCBI-GEO ]   GET1 [ EBI - ARRAY_EXPRESS ]   GET1 [ SEEK ]   GET1 [ MEM ]
Gene Expression Viewer (FireBrowse)GET1 [ Firebrowse - Broad ]
GenevisibleExpression of GET1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)7485
GTEX Portal (Tissue expression)GET1
Human Protein AtlasENSG00000182093-GET1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO00258   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO00258  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO00258
Splice isoforms : SwissVarO00258
PhosPhoSitePlusO00258
Domains : Interpro (EBI)WRB/Get1   
Domain families : Pfam (Sanger)CHD5 (PF04420)   
Domain families : Pfam (NCBI)pfam04420   
Conserved Domain (NCBI)GET1
DMDM Disease mutations7485
Blocks (Seattle)GET1
SuperfamilyO00258
Human Protein Atlas [tissue]ENSG00000182093-GET1 [tissue]
Peptide AtlasO00258
HPRD04224
IPIIPI00010873   IPI00921876   IPI00658165   IPI01021082   IPI00916485   IPI00916351   IPI00916769   IPI00916601   
Protein Interaction databases
DIP (DOE-UCLA)O00258
IntAct (EBI)O00258
FunCoupENSG00000182093
BioGRIDGET1
STRING (EMBL)GET1
ZODIACGET1
Ontologies - Pathways
QuickGOO00258
Ontology : AmiGOnucleus  endoplasmic reticulum  endoplasmic reticulum membrane  integral component of membrane  tail-anchored membrane protein insertion into ER membrane  
Ontology : EGO-EBInucleus  endoplasmic reticulum  endoplasmic reticulum membrane  integral component of membrane  tail-anchored membrane protein insertion into ER membrane  
NDEx NetworkGET1
Atlas of Cancer Signalling NetworkGET1
Wikipedia pathwaysGET1
Orthology - Evolution
OrthoDB7485
GeneTree (enSembl)ENSG00000182093
Phylogenetic Trees/Animal Genes : TreeFamGET1
HOGENOMO00258
Homologs : HomoloGeneGET1
Homology/Alignments : Family Browser (UCSC)GET1
Gene fusions - Rearrangements
Fusion PortalWRB NLK
Fusion PortalWRB KCNJ15
Fusion : QuiverGET1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGET1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GET1
dbVarGET1
ClinVarGET1
1000_GenomesGET1 
Exome Variant ServerGET1
GNOMAD BrowserENSG00000182093
Varsome BrowserGET1
Genetic variants : HAPMAP7485
Genomic Variants (DGV)GET1 [DGVbeta]
DECIPHERGET1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGET1 
Mutations
ICGC Data PortalGET1 
TCGA Data PortalGET1 
Broad Tumor PortalGET1
OASIS PortalGET1 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDGET1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GET1
DgiDB (Drug Gene Interaction Database)GET1
DoCM (Curated mutations)GET1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GET1 (select a term)
intoGenGET1
Cancer3DGET1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602915   
Orphanet
DisGeNETGET1
MedgenGET1
Genetic Testing Registry GET1
NextProtO00258 [Medical]
TSGene7485
GENETestsGET1
Target ValidationGET1
Huge Navigator GET1 [HugePedia]
snp3D : Map Gene to Disease7485
BioCentury BCIQGET1
ClinGenGET1
Clinical trials, drugs, therapy
Protein Interactions : CTD7485
Pharm GKB GenePA37391
Clinical trialGET1
Miscellaneous
canSAR (ICR)GET1 (select the gene name)
HarmonizomeGET1
DataMed IndexGET1
Probes
Litterature
PubMed16 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGET1
EVEXGET1
GoPubMedGET1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Sat Aug 22 19:03:31 CEST 2020

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