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GET3 (guided entry of tail-anchored proteins factor 3, ATPase)

Identity

Alias (NCBI)ARSA-I
ARSA1
ASNA-I
ASNA1
TRC40
HGNC (Hugo) GET3
HGNC Alias symbARSA-I
TRC40
HGNC Alias namegolgi to ER traffic 3 homolog (S. cerevisiae)
 transmembrane domain recognition complex, 40kDa
HGNC Previous nameASNA1
HGNC Previous namearsA (bacterial) arsenite transporter, ATP-binding, homolog 1
LocusID (NCBI) 439
Atlas_Id 57981
Location 19p13.13  [Link to chromosome band 19p13]
Location_base_pair Starts at 12737497 and ends at 12748323 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute



External links

 

Nomenclature
HGNC (Hugo)GET3   752
Cards
Entrez_Gene (NCBI)GET3    guided entry of tail-anchored proteins factor 3, ATPase
AliasesARSA-I; ARSA1; ASNA-I; ASNA1; 
TRC40
GeneCards (Weizmann)GET3
Ensembl hg19 (Hinxton)ENSG00000198356 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000198356 [Gene_View]  ENSG00000198356 [Sequence]  chr19:12737497-12748323 [Contig_View]  GET3 [Vega]
ICGC DataPortalENSG00000198356
TCGA cBioPortalGET3
AceView (NCBI)GET3
Genatlas (Paris)GET3
SOURCE (Princeton)GET3
Genetics Home Reference (NIH)GET3
Genomic and cartography
GoldenPath hg38 (UCSC)GET3  -     chr19:12737497-12748323 +  19p13.13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GET3  -     19p13.13   [Description]    (hg19-Feb_2009)
GoldenPathGET3 - 19p13.13 [CytoView hg19]  GET3 - 19p13.13 [CytoView hg38]
ImmunoBaseENSG00000198356
Genome Data Viewer NCBIGET3 [Mapview hg19]  
OMIM601913   
Gene and transcription
Genbank (Entrez)AF047469 AK223363 AK291855 AK293588 BC002651
RefSeq transcript (Entrez)NM_001371488 NM_001371489 NM_004317
Consensus coding sequences : CCDS (NCBI)GET3
Gene ExpressionGET3 [ NCBI-GEO ]   GET3 [ EBI - ARRAY_EXPRESS ]   GET3 [ SEEK ]   GET3 [ MEM ]
Gene Expression Viewer (FireBrowse)GET3 [ Firebrowse - Broad ]
GenevisibleExpression of GET3 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)439
GTEX Portal (Tissue expression)GET3
Human Protein AtlasENSG00000198356-GET3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO43681   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO43681  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO43681
PhosPhoSitePlusO43681
Domains : Interpro (EBI)Anion-transp_ATPase-like_dom    ATPase_ArsA/GET3    ATPase_ArsA/GET3_euk    P-loop_NTPase   
Domain families : Pfam (Sanger)ArsA_ATPase (PF02374)   
Domain families : Pfam (NCBI)pfam02374   
Conserved Domain (NCBI)GET3
PDB (RSDB)6SO5   
PDB Europe6SO5   
PDB (PDBSum)6SO5   
PDB (IMB)6SO5   
Structural Biology KnowledgeBase6SO5   
SCOP (Structural Classification of Proteins)6SO5   
CATH (Classification of proteins structures)6SO5   
SuperfamilyO43681
AlphaFold pdb e-kbO43681   
Human Protein Atlas [tissue]ENSG00000198356-GET3 [tissue]
Protein Interaction databases
DIP (DOE-UCLA)O43681
IntAct (EBI)O43681
BioGRIDGET3
STRING (EMBL)GET3
ZODIACGET3
Ontologies - Pathways
QuickGOO43681
Ontology : AmiGOprotein binding  ATP binding  nucleoplasm  nucleolus  cytoplasm  posttranslational protein targeting to endoplasmic reticulum membrane  arsenite transmembrane transporter activity  arsenite transport  hydrolase activity  ATPase  GET complex  GET complex  GET complex  metal ion binding  extracellular exosome  tail-anchored membrane protein insertion into ER membrane  tail-anchored membrane protein insertion into ER membrane  
Ontology : EGO-EBIprotein binding  ATP binding  nucleoplasm  nucleolus  cytoplasm  posttranslational protein targeting to endoplasmic reticulum membrane  arsenite transmembrane transporter activity  arsenite transport  hydrolase activity  ATPase  GET complex  GET complex  GET complex  metal ion binding  extracellular exosome  tail-anchored membrane protein insertion into ER membrane  tail-anchored membrane protein insertion into ER membrane  
NDEx NetworkGET3
Atlas of Cancer Signalling NetworkGET3
Wikipedia pathwaysGET3
Orthology - Evolution
OrthoDB439
GeneTree (enSembl)ENSG00000198356
Phylogenetic Trees/Animal Genes : TreeFamGET3
Homologs : HomoloGeneGET3
Homology/Alignments : Family Browser (UCSC)GET3
Gene fusions - Rearrangements
Fusion : QuiverGET3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGET3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GET3
dbVarGET3
ClinVarGET3
MonarchGET3
1000_GenomesGET3 
Exome Variant ServerGET3
GNOMAD BrowserENSG00000198356
Varsome BrowserGET3
ACMGGET3 variants
VarityO43681
Genomic Variants (DGV)GET3 [DGVbeta]
DECIPHERGET3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGET3 
Mutations
ICGC Data PortalGET3 
TCGA Data PortalGET3 
Broad Tumor PortalGET3
OASIS PortalGET3 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDGET3
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaGET3
DgiDB (Drug Gene Interaction Database)GET3
DoCM (Curated mutations)GET3
CIViC (Clinical Interpretations of Variants in Cancer)GET3
Cancer3DGET3
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601913   
Orphanet
DisGeNETGET3
MedgenGET3
Genetic Testing Registry GET3
NextProtO43681 [Medical]
GENETestsGET3
Target ValidationGET3
Huge Navigator GET3 [HugePedia]
ClinGenGET3
Clinical trials, drugs, therapy
MyCancerGenomeGET3
Protein Interactions : CTDGET3
PharosO43681
Clinical trialGET3
Miscellaneous
canSAR (ICR)GET3
HarmonizomeGET3
DataMed IndexGET3
Probes
Litterature
PubMed67 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXGET3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:10:38 CEST 2021

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