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GET4 (golgi to ER traffic protein 4)

Identity

Alias_namesC7orf20
chromosome 7 open reading frame 20
golgi to ER traffic protein 4 homolog (S. cerevisiae)
Alias_symbol (synonym)CGI-20
H_NH1244M04.5
CEE
TRC35
Other alias
HGNC (Hugo) GET4
LocusID (NCBI) 51608
Atlas_Id 63753
Location 7p22.3  [Link to chromosome band 7p22]
Location_base_pair Starts at 876554 and ends at 896434 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
STK17A (7p13) / GET4 (7p22.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Leukemias implicated (Data extracted from papers in the Atlas) [ 2 ]
  t(7;7)(p22;p22) GET4/TNRC18
t(7;7)(p22;p22) GET4/TNRC18

External links

Nomenclature
HGNC (Hugo)GET4   21690
Cards
Entrez_Gene (NCBI)GET4  51608  golgi to ER traffic protein 4
AliasesC7orf20; CEE; CGI-20; TRC35
GeneCards (Weizmann)GET4
Ensembl hg19 (Hinxton)ENSG00000239857 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000239857 [Gene_View]  ENSG00000239857 [Sequence]  chr7:876554-896434 [Contig_View]  GET4 [Vega]
ICGC DataPortalENSG00000239857
TCGA cBioPortalGET4
AceView (NCBI)GET4
Genatlas (Paris)GET4
WikiGenes51608
SOURCE (Princeton)GET4
Genetics Home Reference (NIH)GET4
Genomic and cartography
GoldenPath hg38 (UCSC)GET4  -     chr7:876554-896434 +  7p22.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GET4  -     7p22.3   [Description]    (hg19-Feb_2009)
EnsemblGET4 - 7p22.3 [CytoView hg19]  GET4 - 7p22.3 [CytoView hg38]
Mapping of homologs : NCBIGET4 [Mapview hg19]  GET4 [Mapview hg38]
OMIM612056   
Gene and transcription
Genbank (Entrez)AF132954 AK023560 AK024305 AK097899 AK124149
RefSeq transcript (Entrez)NM_015949
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GET4
Cluster EST : UnigeneHs.743756 [ NCBI ]
CGAP (NCI)Hs.743756
Alternative Splicing GalleryENSG00000239857
Gene ExpressionGET4 [ NCBI-GEO ]   GET4 [ EBI - ARRAY_EXPRESS ]   GET4 [ SEEK ]   GET4 [ MEM ]
Gene Expression Viewer (FireBrowse)GET4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)51608
GTEX Portal (Tissue expression)GET4
Human Protein AtlasENSG00000239857-GET4 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ7L5D6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ7L5D6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ7L5D6
Splice isoforms : SwissVarQ7L5D6
PhosPhoSitePlusQ7L5D6
Domains : Interpro (EBI)UPF0363   
Domain families : Pfam (Sanger)DUF410 (PF04190)   
Domain families : Pfam (NCBI)pfam04190   
Conserved Domain (NCBI)GET4
DMDM Disease mutations51608
Blocks (Seattle)GET4
SuperfamilyQ7L5D6
Human Protein Atlas [tissue]ENSG00000239857-GET4 [tissue]
Peptide AtlasQ7L5D6
HPRD12909
IPIIPI00893923   IPI00419575   IPI00894419   IPI00893782   IPI00894139   
Protein Interaction databases
DIP (DOE-UCLA)Q7L5D6
IntAct (EBI)Q7L5D6
FunCoupENSG00000239857
BioGRIDGET4
STRING (EMBL)GET4
ZODIACGET4
Ontologies - Pathways
QuickGOQ7L5D6
Ontology : AmiGOprotein binding  nucleoplasm  nucleolus  cytoplasm  cytosol  transport  chaperone binding  cytoplasmic sequestering of protein  tail-anchored membrane protein insertion into ER membrane  BAT3 complex  maintenance of unfolded protein involved in ERAD pathway  
Ontology : EGO-EBIprotein binding  nucleoplasm  nucleolus  cytoplasm  cytosol  transport  chaperone binding  cytoplasmic sequestering of protein  tail-anchored membrane protein insertion into ER membrane  BAT3 complex  maintenance of unfolded protein involved in ERAD pathway  
NDEx NetworkGET4
Atlas of Cancer Signalling NetworkGET4
Wikipedia pathwaysGET4
Orthology - Evolution
OrthoDB51608
GeneTree (enSembl)ENSG00000239857
Phylogenetic Trees/Animal Genes : TreeFamGET4
HOVERGENQ7L5D6
HOGENOMQ7L5D6
Homologs : HomoloGeneGET4
Homology/Alignments : Family Browser (UCSC)GET4
Gene fusions - Rearrangements
Fusion : QuiverGET4
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGET4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GET4
dbVarGET4
ClinVarGET4
1000_GenomesGET4 
Exome Variant ServerGET4
ExAC (Exome Aggregation Consortium)ENSG00000239857
GNOMAD BrowserENSG00000239857
Varsome BrowserGET4
Genetic variants : HAPMAP51608
Genomic Variants (DGV)GET4 [DGVbeta]
DECIPHERGET4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGET4 
Mutations
ICGC Data PortalGET4 
TCGA Data PortalGET4 
Broad Tumor PortalGET4
OASIS PortalGET4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGET4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGET4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GET4
DgiDB (Drug Gene Interaction Database)GET4
DoCM (Curated mutations)GET4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GET4 (select a term)
intoGenGET4
Cancer3DGET4(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612056   
Orphanet
DisGeNETGET4
MedgenGET4
Genetic Testing Registry GET4
NextProtQ7L5D6 [Medical]
TSGene51608
GENETestsGET4
Target ValidationGET4
Huge Navigator GET4 [HugePedia]
snp3D : Map Gene to Disease51608
BioCentury BCIQGET4
ClinGenGET4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD51608
Chemical/Pharm GKB GenePA165618100
Clinical trialGET4
Miscellaneous
canSAR (ICR)GET4 (select the gene name)
Probes
Litterature
PubMed1 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGET4
EVEXGET4
GoPubMedGET4
iHOPGET4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Jul 30 13:47:11 CEST 2018
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