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GFAP (glial fibrillary acidic protein)

Identity

Other names-
HGNC (Hugo) GFAP
LocusID (NCBI) 2670
Location 17q21.31
Location_base_pair Starts at 42987035 and ends at 42992920 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)GFAP   4235
Cards
Entrez_Gene (NCBI)GFAP  2670  glial fibrillary acidic protein
GeneCards (Weizmann)GFAP
Ensembl (Hinxton)ENSG00000131095 [Gene_View]  chr17:42987035-42992920 [Contig_View]  GFAP [Vega]
ICGC DataPortalENSG00000131095
cBioPortalGFAP
AceView (NCBI)GFAP
Genatlas (Paris)GFAP
WikiGenes2670
SOURCE (Princeton)NM_001131019 NM_001242376 NM_002055
Genomic and cartography
GoldenPath (UCSC)GFAP  -  17q21.31   chr17:42987035-42992920 -  17q21.31   [Description]    (hg19-Feb_2009)
EnsemblGFAP - 17q21.31 [CytoView]
Mapping of homologs : NCBIGFAP [Mapview]
OMIM137780   203450   
Gene and transcription
Genbank (Entrez)AF419299 AJ306447 AK098380 AK098758 AK124465
RefSeq transcript (Entrez)NM_001131019 NM_001242376 NM_002055
RefSeq genomic (Entrez)AC_000149 NC_000017 NC_018928 NG_008401 NT_010783 NW_001838437 NW_004929407
Consensus coding sequences : CCDS (NCBI)GFAP
Cluster EST : UnigeneHs.514227 [ NCBI ]
CGAP (NCI)Hs.514227
Alternative Splicing : Fast-db (Paris)GSHG0013472
Alternative Splicing GalleryENSG00000131095
Gene ExpressionGFAP [ NCBI-GEO ]     GFAP [ SEEK ]   GFAP [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP14136 (Uniprot)
NextProtP14136  [Medical]
With graphics : InterProP14136
Splice isoforms : SwissVarP14136 (Swissvar)
Domaine pattern : Prosite (Expaxy)IF (PS00226)   
Domains : Interpro (EBI)GFAP [organisation]   IF [organisation]   Intermediate_filament_CS [organisation]  
Related proteins : CluSTrP14136
Domain families : Pfam (Sanger)Filament (PF00038)   
Domain families : Pfam (NCBI)pfam00038   
DMDM Disease mutations2670
Blocks (Seattle)P14136
Human Protein AtlasENSG00000131095 [gene] [tissue] [antibody] [cell] [cancer]
Peptide AtlasP14136
HPRD00675
IPIIPI00025363   IPI00383815   IPI00443478   IPI00909238   IPI01011386   IPI01009054   IPI00982111   
Protein Interaction databases
DIP (DOE-UCLA)P14136
IntAct (EBI)P14136
FunCoupENSG00000131095
BioGRIDGFAP
InParanoidP14136
Interologous Interaction database P14136
IntegromeDBGFAP
STRING (EMBL)GFAP
Ontologies - Pathways
Ontology : AmiGOintegrin binding  structural constituent of cytoskeleton  cytoplasm  cytosol  intermediate filament  response to wounding  positive regulation of Schwann cell proliferation  negative regulation of neuron projection development  astrocyte development  membrane  kinase binding  extracellular matrix organization  neuron projection regeneration  cell body  intermediate filament organization  regulation of neurotransmitter uptake  Bergmann glial cell differentiation  long-term synaptic potentiation  astrocyte projection  
Ontology : EGO-EBIintegrin binding  structural constituent of cytoskeleton  cytoplasm  cytosol  intermediate filament  response to wounding  positive regulation of Schwann cell proliferation  negative regulation of neuron projection development  astrocyte development  membrane  kinase binding  extracellular matrix organization  neuron projection regeneration  cell body  intermediate filament organization  regulation of neurotransmitter uptake  Bergmann glial cell differentiation  long-term synaptic potentiation  astrocyte projection  
Pathways : BIOCARTAPrion Pathway [Genes]   
Protein Interaction DatabaseGFAP
Wikipedia pathwaysGFAP
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)GFAP
snp3D : Map Gene to Disease2670
SNP (GeneSNP Utah)GFAP
SNP : HGBaseGFAP
Genetic variants : HAPMAPGFAP
Exome VariantGFAP
1000_GenomesGFAP 
ICGC programENSG00000131095 
Somatic Mutations in Cancer : COSMICGFAP 
CONAN: Copy Number AnalysisGFAP 
Mutations and Diseases : HGMDGFAP
Genomic VariantsGFAP  GFAP [DGVbeta]
dbVarGFAP
ClinVarGFAP
Pred. of missensesPolyPhen-2  SIFT(SG)  SIFT(JCVI)  Align-GVGD  MutAssessor  Mutanalyser  
Pred. splicesGeneSplicer  Human Splicing Finder  MaxEntScan  
Diseases
OMIM137780    203450   
MedgenGFAP
GENETestsGFAP
Disease Genetic AssociationGFAP
Huge Navigator GFAP [HugePedia]  GFAP [HugeCancerGEM]
General knowledge
Homologs : HomoloGeneGFAP
Homology/Alignments : Family Browser (UCSC)GFAP
Phylogenetic Trees/Animal Genes : TreeFamGFAP
Chemical/Protein Interactions : CTD2670
Chemical/Pharm GKB GenePA28647
Clinical trialGFAP
Cancer Resource (Charite)ENSG00000131095
Other databases
Probes
Litterature
PubMed181 Pubmed reference(s) in Entrez
CoreMineGFAP
iHOPGFAP
OncoSearchGFAP
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jul 30 13:56:06 CEST 2014

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