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GFM2 (G elongation factor mitochondrial 2)

Identity

Alias_symbol (synonym)EFG2
FLJ21661
Other aliasEF-G2mt
MRRF2
MST027
MSTP027
RRF2
RRF2mt
hEFG2
mEF-G 2
HGNC (Hugo) GFM2
LocusID (NCBI) 84340
Atlas_Id 63755
Location 5q13.3  [Link to chromosome band 5q13]
Location_base_pair Starts at 74721204 and ends at 74767371 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
GFM2 (5q13.3) / SPAG6 (10p12.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GFM2   29682
Cards
Entrez_Gene (NCBI)GFM2  84340  G elongation factor mitochondrial 2
AliasesEF-G2mt; EFG2; MRRF2; MST027; 
MSTP027; RRF2; RRF2mt; hEFG2; mEF-G
GeneCards (Weizmann)GFM2
Ensembl hg19 (Hinxton)ENSG00000164347 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000164347 [Gene_View]  chr5:74721204-74767371 [Contig_View]  GFM2 [Vega]
ICGC DataPortalENSG00000164347
TCGA cBioPortalGFM2
AceView (NCBI)GFM2
Genatlas (Paris)GFM2
WikiGenes84340
SOURCE (Princeton)GFM2
Genetics Home Reference (NIH)GFM2
Genomic and cartography
GoldenPath hg38 (UCSC)GFM2  -     chr5:74721204-74767371 -  5q13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GFM2  -     5q13.3   [Description]    (hg19-Feb_2009)
EnsemblGFM2 - 5q13.3 [CytoView hg19]  GFM2 - 5q13.3 [CytoView hg38]
Mapping of homologs : NCBIGFM2 [Mapview hg19]  GFM2 [Mapview hg38]
OMIM606544   
Gene and transcription
Genbank (Entrez)AA418187 AF111808 AF367997 AK025314 AK307839
RefSeq transcript (Entrez)NM_001281302 NM_032380 NM_170681 NM_170691
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GFM2
Cluster EST : UnigeneHs.656975 [ NCBI ]
CGAP (NCI)Hs.656975
Alternative Splicing GalleryENSG00000164347
Gene ExpressionGFM2 [ NCBI-GEO ]   GFM2 [ EBI - ARRAY_EXPRESS ]   GFM2 [ SEEK ]   GFM2 [ MEM ]
Gene Expression Viewer (FireBrowse)GFM2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)84340
GTEX Portal (Tissue expression)GFM2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ969S9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ969S9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ969S9
Splice isoforms : SwissVarQ969S9
PhosPhoSitePlusQ969S9
Domaine pattern : Prosite (Expaxy)G_TR_1 (PS00301)    G_TR_2 (PS51722)   
Domains : Interpro (EBI)EFG2    EFG_III-V    EFG_V    EFTu-like_2    G_TR_CS    P-loop_NTPase    Ribosomal_S5_D2-typ_fold    Ribosomal_S5_D2-typ_fold_subgr    Small_GTP-bd_dom    TF_GTP-bd_dom    Transl_B-barrel    Transl_elong_EFG/EF2_IV   
Domain families : Pfam (Sanger)EFG_C (PF00679)    EFG_II (PF14492)    EFG_IV (PF03764)    GTP_EFTU_D2 (PF03144)   
Domain families : Pfam (NCBI)pfam00679    pfam14492    pfam03764    pfam03144   
Domain families : Smart (EMBL)EFG_C (SM00838)  EFG_IV (SM00889)  
Conserved Domain (NCBI)GFM2
DMDM Disease mutations84340
Blocks (Seattle)GFM2
SuperfamilyQ969S9
Human Protein AtlasENSG00000164347
Peptide AtlasQ969S9
HPRD09413
IPIIPI00216419   IPI00945410   IPI00946969   IPI00172648   IPI01018878   IPI00071703   IPI00966775   IPI00966453   
Protein Interaction databases
DIP (DOE-UCLA)Q969S9
IntAct (EBI)Q969S9
FunCoupENSG00000164347
BioGRIDGFM2
STRING (EMBL)GFM2
ZODIACGFM2
Ontologies - Pathways
QuickGOQ969S9
Ontology : AmiGOtranslation elongation factor activity  GTPase activity  GTPase activity  protein binding  GTP binding  mitochondrial matrix  mitochondrial translation  ribosome disassembly  mitochondrial translational elongation  mitochondrial translational termination  
Ontology : EGO-EBItranslation elongation factor activity  GTPase activity  GTPase activity  protein binding  GTP binding  mitochondrial matrix  mitochondrial translation  ribosome disassembly  mitochondrial translational elongation  mitochondrial translational termination  
NDEx NetworkGFM2
Atlas of Cancer Signalling NetworkGFM2
Wikipedia pathwaysGFM2
Orthology - Evolution
OrthoDB84340
GeneTree (enSembl)ENSG00000164347
Phylogenetic Trees/Animal Genes : TreeFamGFM2
HOVERGENQ969S9
HOGENOMQ969S9
Homologs : HomoloGeneGFM2
Homology/Alignments : Family Browser (UCSC)GFM2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGFM2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GFM2
dbVarGFM2
ClinVarGFM2
1000_GenomesGFM2 
Exome Variant ServerGFM2
ExAC (Exome Aggregation Consortium)GFM2 (select the gene name)
Genetic variants : HAPMAP84340
Genomic Variants (DGV)GFM2 [DGVbeta]
DECIPHERGFM2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGFM2 
Mutations
ICGC Data PortalGFM2 
TCGA Data PortalGFM2 
Broad Tumor PortalGFM2
OASIS PortalGFM2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGFM2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGFM2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch GFM2
DgiDB (Drug Gene Interaction Database)GFM2
DoCM (Curated mutations)GFM2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GFM2 (select a term)
intoGenGFM2
Cancer3DGFM2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606544   
Orphanet
MedgenGFM2
Genetic Testing Registry GFM2
NextProtQ969S9 [Medical]
TSGene84340
GENETestsGFM2
Target ValidationGFM2
Huge Navigator GFM2 [HugePedia]
snp3D : Map Gene to Disease84340
BioCentury BCIQGFM2
ClinGenGFM2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD84340
Chemical/Pharm GKB GenePA134949527
Clinical trialGFM2
Miscellaneous
canSAR (ICR)GFM2 (select the gene name)
Probes
Litterature
PubMed14 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGFM2
EVEXGFM2
GoPubMedGFM2
iHOPGFM2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 15:50:31 CEST 2017

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