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GFPT2 (glutamine-fructose-6-phosphate transaminase 2)

Identity

Alias_symbol (synonym)GFAT2
Other alias
HGNC (Hugo) GFPT2
LocusID (NCBI) 9945
Atlas_Id 63759
Location 5q35.3  [Link to chromosome band 5q35]
Location_base_pair Starts at 179727700 and ends at 179780315 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
GFPT2 (5q35.3) / GFPT2 (5q35.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GFPT2   4242
Cards
Entrez_Gene (NCBI)GFPT2  9945  glutamine-fructose-6-phosphate transaminase 2
AliasesGFAT2
GeneCards (Weizmann)GFPT2
Ensembl hg19 (Hinxton)ENSG00000131459 [Gene_View]  chr5:179727700-179780315 [Contig_View]  GFPT2 [Vega]
Ensembl hg38 (Hinxton)ENSG00000131459 [Gene_View]  chr5:179727700-179780315 [Contig_View]  GFPT2 [Vega]
ICGC DataPortalENSG00000131459
TCGA cBioPortalGFPT2
AceView (NCBI)GFPT2
Genatlas (Paris)GFPT2
WikiGenes9945
SOURCE (Princeton)GFPT2
Genetics Home Reference (NIH)GFPT2
Genomic and cartography
GoldenPath hg19 (UCSC)GFPT2  -     chr5:179727700-179780315 -  5q35.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)GFPT2  -     5q35.3   [Description]    (hg38-Dec_2013)
EnsemblGFPT2 - 5q35.3 [CytoView hg19]  GFPT2 - 5q35.3 [CytoView hg38]
Mapping of homologs : NCBIGFPT2 [Mapview hg19]  GFPT2 [Mapview hg38]
OMIM603865   
Gene and transcription
Genbank (Entrez)AB016789 AK001242 AK022507 AK297750 AK314551
RefSeq transcript (Entrez)NM_005110
RefSeq genomic (Entrez)NC_000005 NC_018916 NT_023133 NW_004929325
Consensus coding sequences : CCDS (NCBI)GFPT2
Cluster EST : UnigeneHs.696497 [ NCBI ]
CGAP (NCI)Hs.696497
Alternative Splicing GalleryENSG00000131459
Gene ExpressionGFPT2 [ NCBI-GEO ]   GFPT2 [ EBI - ARRAY_EXPRESS ]   GFPT2 [ SEEK ]   GFPT2 [ MEM ]
Gene Expression Viewer (FireBrowse)GFPT2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9945
GTEX Portal (Tissue expression)GFPT2
Protein : pattern, domain, 3D structure
UniProt/SwissProtO94808   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO94808  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO94808
Splice isoforms : SwissVarO94808
Catalytic activity : Enzyme2.6.1.16 [ Enzyme-Expasy ]   2.6.1.162.6.1.16 [ IntEnz-EBI ]   2.6.1.16 [ BRENDA ]   2.6.1.16 [ KEGG ]   
PhosPhoSitePlusO94808
Domaine pattern : Prosite (Expaxy)GATASE_TYPE_2 (PS51278)    SIS (PS51464)   
Domains : Interpro (EBI)GATase_2_dom    GATase_dom    GlmS_trans    Ntn_hydrolases_N    SIS   
Domain families : Pfam (Sanger)GATase_2 (PF00310)    SIS (PF01380)   
Domain families : Pfam (NCBI)pfam00310    pfam01380   
Conserved Domain (NCBI)GFPT2
DMDM Disease mutations9945
Blocks (Seattle)GFPT2
SuperfamilyO94808
Human Protein AtlasENSG00000131459
Peptide AtlasO94808
HPRD04842
IPIIPI00216159   IPI00967007   IPI00974350   
Protein Interaction databases
DIP (DOE-UCLA)O94808
IntAct (EBI)O94808
FunCoupENSG00000131459
BioGRIDGFPT2
STRING (EMBL)GFPT2
ZODIACGFPT2
Ontologies - Pathways
QuickGOO94808
Ontology : AmiGOglutamine-fructose-6-phosphate transaminase (isomerizing) activity  cytosol  fructose 6-phosphate metabolic process  UDP-N-acetylglucosamine biosynthetic process  UDP-N-acetylglucosamine biosynthetic process  energy reserve metabolic process  dolichol-linked oligosaccharide biosynthetic process  glutamine metabolic process  protein N-linked glycosylation via asparagine  carbohydrate binding  post-translational protein modification  cellular protein metabolic process  
Ontology : EGO-EBIglutamine-fructose-6-phosphate transaminase (isomerizing) activity  cytosol  fructose 6-phosphate metabolic process  UDP-N-acetylglucosamine biosynthetic process  UDP-N-acetylglucosamine biosynthetic process  energy reserve metabolic process  dolichol-linked oligosaccharide biosynthetic process  glutamine metabolic process  protein N-linked glycosylation via asparagine  carbohydrate binding  post-translational protein modification  cellular protein metabolic process  
Pathways : KEGGAlanine, aspartate and glutamate metabolism    Amino sugar and nucleotide sugar metabolism   
NDEx NetworkGFPT2
Atlas of Cancer Signalling NetworkGFPT2
Wikipedia pathwaysGFPT2
Orthology - Evolution
OrthoDB9945
GeneTree (enSembl)ENSG00000131459
Phylogenetic Trees/Animal Genes : TreeFamGFPT2
HOVERGENO94808
HOGENOMO94808
Homologs : HomoloGeneGFPT2
Homology/Alignments : Family Browser (UCSC)GFPT2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGFPT2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GFPT2
dbVarGFPT2
ClinVarGFPT2
1000_GenomesGFPT2 
Exome Variant ServerGFPT2
ExAC (Exome Aggregation Consortium)GFPT2 (select the gene name)
Genetic variants : HAPMAP9945
Genomic Variants (DGV)GFPT2 [DGVbeta]
DECIPHER (Syndromes)5:179727700-179780315  ENSG00000131459
CONAN: Copy Number AnalysisGFPT2 
Mutations
ICGC Data PortalGFPT2 
TCGA Data PortalGFPT2 
Broad Tumor PortalGFPT2
OASIS PortalGFPT2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGFPT2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGFPT2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GFPT2
DgiDB (Drug Gene Interaction Database)GFPT2
DoCM (Curated mutations)GFPT2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GFPT2 (select a term)
intoGenGFPT2
Cancer3DGFPT2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603865   
Orphanet
MedgenGFPT2
Genetic Testing Registry GFPT2
NextProtO94808 [Medical]
TSGene9945
GENETestsGFPT2
Huge Navigator GFPT2 [HugePedia]
snp3D : Map Gene to Disease9945
BioCentury BCIQGFPT2
ClinGenGFPT2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9945
Chemical/Pharm GKB GenePA28652
Clinical trialGFPT2
Miscellaneous
canSAR (ICR)GFPT2 (select the gene name)
Probes
Litterature
PubMed18 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGFPT2
EVEXGFPT2
GoPubMedGFPT2
iHOPGFPT2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:06:00 CET 2017

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