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GFRA4 (GDNF family receptor alpha 4)

Identity

Other alias-
HGNC (Hugo) GFRA4
LocusID (NCBI) 64096
Atlas_Id 63760
Location 20p13  [Link to chromosome band 20p13]
Location_base_pair Starts at 3659292 and ends at 3663399 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GFRA4   13821
Cards
Entrez_Gene (NCBI)GFRA4  64096  GDNF family receptor alpha 4
Aliases
GeneCards (Weizmann)GFRA4
Ensembl hg19 (Hinxton)ENSG00000125861 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000125861 [Gene_View]  chr20:3659292-3663399 [Contig_View]  GFRA4 [Vega]
ICGC DataPortalENSG00000125861
TCGA cBioPortalGFRA4
AceView (NCBI)GFRA4
Genatlas (Paris)GFRA4
WikiGenes64096
SOURCE (Princeton)GFRA4
Genetics Home Reference (NIH)GFRA4
Genomic and cartography
GoldenPath hg38 (UCSC)GFRA4  -     chr20:3659292-3663399 -  20p13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GFRA4  -     20p13   [Description]    (hg19-Feb_2009)
EnsemblGFRA4 - 20p13 [CytoView hg19]  GFRA4 - 20p13 [CytoView hg38]
Mapping of homologs : NCBIGFRA4 [Mapview hg19]  GFRA4 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AF253318 AJ291673 AJ291674 AJ291675 BC172271
RefSeq transcript (Entrez)NM_022139 NM_145762 NM_145763
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GFRA4
Cluster EST : UnigeneHs.302025 [ NCBI ]
CGAP (NCI)Hs.302025
Alternative Splicing GalleryENSG00000125861
Gene ExpressionGFRA4 [ NCBI-GEO ]   GFRA4 [ EBI - ARRAY_EXPRESS ]   GFRA4 [ SEEK ]   GFRA4 [ MEM ]
Gene Expression Viewer (FireBrowse)GFRA4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)64096
GTEX Portal (Tissue expression)GFRA4
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9GZZ7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9GZZ7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9GZZ7
Splice isoforms : SwissVarQ9GZZ7
PhosPhoSitePlusQ9GZZ7
Domains : Interpro (EBI)GDNF/GAS1    GDNF_rcpt   
Domain families : Pfam (Sanger)GDNF (PF02351)   
Domain families : Pfam (NCBI)pfam02351   
Domain families : Smart (EMBL)GDNF (SM00907)  
Conserved Domain (NCBI)GFRA4
DMDM Disease mutations64096
Blocks (Seattle)GFRA4
SuperfamilyQ9GZZ7
Human Protein AtlasENSG00000125861
Peptide AtlasQ9GZZ7
HPRD11003
IPIIPI00015540   IPI00005510   IPI00015537   
Protein Interaction databases
DIP (DOE-UCLA)Q9GZZ7
IntAct (EBI)Q9GZZ7
FunCoupENSG00000125861
BioGRIDGFRA4
STRING (EMBL)GFRA4
ZODIACGFRA4
Ontologies - Pathways
QuickGOQ9GZZ7
Ontology : AmiGOMAPK cascade  Ras guanyl-nucleotide exchange factor activity  extracellular space  intracellular  plasma membrane  axon guidance  glial cell-derived neurotrophic factor receptor activity  negative regulation of ossification  anchored component of membrane  glial cell-derived neurotrophic factor receptor signaling pathway  positive regulation of GTPase activity  extracellular exosome  
Ontology : EGO-EBIMAPK cascade  Ras guanyl-nucleotide exchange factor activity  extracellular space  intracellular  plasma membrane  axon guidance  glial cell-derived neurotrophic factor receptor activity  negative regulation of ossification  anchored component of membrane  glial cell-derived neurotrophic factor receptor signaling pathway  positive regulation of GTPase activity  extracellular exosome  
NDEx NetworkGFRA4
Atlas of Cancer Signalling NetworkGFRA4
Wikipedia pathwaysGFRA4
Orthology - Evolution
OrthoDB64096
GeneTree (enSembl)ENSG00000125861
Phylogenetic Trees/Animal Genes : TreeFamGFRA4
HOVERGENQ9GZZ7
HOGENOMQ9GZZ7
Homologs : HomoloGeneGFRA4
Homology/Alignments : Family Browser (UCSC)GFRA4
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGFRA4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GFRA4
dbVarGFRA4
ClinVarGFRA4
1000_GenomesGFRA4 
Exome Variant ServerGFRA4
ExAC (Exome Aggregation Consortium)GFRA4 (select the gene name)
Genetic variants : HAPMAP64096
Genomic Variants (DGV)GFRA4 [DGVbeta]
DECIPHERGFRA4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGFRA4 
Mutations
ICGC Data PortalGFRA4 
TCGA Data PortalGFRA4 
Broad Tumor PortalGFRA4
OASIS PortalGFRA4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGFRA4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGFRA4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GFRA4
DgiDB (Drug Gene Interaction Database)GFRA4
DoCM (Curated mutations)GFRA4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GFRA4 (select a term)
intoGenGFRA4
Cancer3DGFRA4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenGFRA4
Genetic Testing Registry GFRA4
NextProtQ9GZZ7 [Medical]
TSGene64096
GENETestsGFRA4
Target ValidationGFRA4
Huge Navigator GFRA4 [HugePedia]
snp3D : Map Gene to Disease64096
BioCentury BCIQGFRA4
ClinGenGFRA4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD64096
Chemical/Pharm GKB GenePA28656
Clinical trialGFRA4
Miscellaneous
canSAR (ICR)GFRA4 (select the gene name)
Probes
Litterature
PubMed8 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGFRA4
EVEXGFRA4
GoPubMedGFRA4
iHOPGFRA4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:09:19 CEST 2017

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