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GFRAL (GDNF family receptor alpha like)

Identity

Alias_namesC6orf144
chromosome 6 open reading frame 144
Alias_symbol (synonym)GRAL
UNQ9356
bA360D14.1
Other alias
HGNC (Hugo) GFRAL
LocusID (NCBI) 389400
Atlas_Id 63761
Location 6p12.1  [Link to chromosome band 6p12]
Location_base_pair Starts at 55327469 and ends at 55402493 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CCDC138 (2q12.3) / GFRAL (6p12.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GFRAL   32789
Cards
Entrez_Gene (NCBI)GFRAL  389400  GDNF family receptor alpha like
AliasesC6orf144; GRAL; UNQ9356; bA360D14.1
GeneCards (Weizmann)GFRAL
Ensembl hg19 (Hinxton)ENSG00000187871 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000187871 [Gene_View]  ENSG00000187871 [Sequence]  chr6:55327469-55402493 [Contig_View]  GFRAL [Vega]
ICGC DataPortalENSG00000187871
TCGA cBioPortalGFRAL
AceView (NCBI)GFRAL
Genatlas (Paris)GFRAL
WikiGenes389400
SOURCE (Princeton)GFRAL
Genetics Home Reference (NIH)GFRAL
Genomic and cartography
GoldenPath hg38 (UCSC)GFRAL  -     chr6:55327469-55402493 +  6p12.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GFRAL  -     6p12.1   [Description]    (hg19-Feb_2009)
EnsemblGFRAL - 6p12.1 [CytoView hg19]  GFRAL - 6p12.1 [CytoView hg38]
Mapping of homologs : NCBIGFRAL [Mapview hg19]  GFRAL [Mapview hg38]
Gene and transcription
Genbank (Entrez)AY358198
RefSeq transcript (Entrez)NM_207410
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GFRAL
Cluster EST : UnigeneHs.526967 [ NCBI ]
CGAP (NCI)Hs.526967
Alternative Splicing GalleryENSG00000187871
Gene ExpressionGFRAL [ NCBI-GEO ]   GFRAL [ EBI - ARRAY_EXPRESS ]   GFRAL [ SEEK ]   GFRAL [ MEM ]
Gene Expression Viewer (FireBrowse)GFRAL [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)389400
GTEX Portal (Tissue expression)GFRAL
Human Protein AtlasENSG00000187871-GFRAL [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6UXV0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6UXV0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6UXV0
Splice isoforms : SwissVarQ6UXV0
PhosPhoSitePlusQ6UXV0
Domains : Interpro (EBI)GDNF/GAS1   
Domain families : Pfam (Sanger)GDNF (PF02351)   
Domain families : Pfam (NCBI)pfam02351   
Domain families : Smart (EMBL)GDNF (SM00907)  
Conserved Domain (NCBI)GFRAL
DMDM Disease mutations389400
Blocks (Seattle)GFRAL
SuperfamilyQ6UXV0
Human Protein Atlas [tissue]ENSG00000187871-GFRAL [tissue]
Peptide AtlasQ6UXV0
HPRD15622
IPIIPI00410476   
Protein Interaction databases
DIP (DOE-UCLA)Q6UXV0
IntAct (EBI)Q6UXV0
FunCoupENSG00000187871
BioGRIDGFRAL
STRING (EMBL)GFRAL
ZODIACGFRAL
Ontologies - Pathways
QuickGOQ6UXV0
Ontology : AmiGOintracellular  plasma membrane  integral component of membrane  stress-activated protein kinase signaling cascade  negative regulation of neuron apoptotic process  negative regulation of extrinsic apoptotic signaling pathway in absence of ligand  
Ontology : EGO-EBIintracellular  plasma membrane  integral component of membrane  stress-activated protein kinase signaling cascade  negative regulation of neuron apoptotic process  negative regulation of extrinsic apoptotic signaling pathway in absence of ligand  
NDEx NetworkGFRAL
Atlas of Cancer Signalling NetworkGFRAL
Wikipedia pathwaysGFRAL
Orthology - Evolution
OrthoDB389400
GeneTree (enSembl)ENSG00000187871
Phylogenetic Trees/Animal Genes : TreeFamGFRAL
HOVERGENQ6UXV0
HOGENOMQ6UXV0
Homologs : HomoloGeneGFRAL
Homology/Alignments : Family Browser (UCSC)GFRAL
Gene fusions - Rearrangements
Fusion : QuiverGFRAL
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGFRAL [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GFRAL
dbVarGFRAL
ClinVarGFRAL
1000_GenomesGFRAL 
Exome Variant ServerGFRAL
ExAC (Exome Aggregation Consortium)ENSG00000187871
GNOMAD BrowserENSG00000187871
Varsome BrowserGFRAL
Genetic variants : HAPMAP389400
Genomic Variants (DGV)GFRAL [DGVbeta]
DECIPHERGFRAL [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGFRAL 
Mutations
ICGC Data PortalGFRAL 
TCGA Data PortalGFRAL 
Broad Tumor PortalGFRAL
OASIS PortalGFRAL [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGFRAL  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGFRAL
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GFRAL
DgiDB (Drug Gene Interaction Database)GFRAL
DoCM (Curated mutations)GFRAL (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GFRAL (select a term)
intoGenGFRAL
Cancer3DGFRAL(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETGFRAL
MedgenGFRAL
Genetic Testing Registry GFRAL
NextProtQ6UXV0 [Medical]
TSGene389400
GENETestsGFRAL
Target ValidationGFRAL
Huge Navigator GFRAL [HugePedia]
snp3D : Map Gene to Disease389400
BioCentury BCIQGFRAL
ClinGenGFRAL
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD389400
Chemical/Pharm GKB GenePA145008357
Clinical trialGFRAL
Miscellaneous
canSAR (ICR)GFRAL (select the gene name)
Probes
Litterature
PubMed3 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGFRAL
EVEXGFRAL
GoPubMedGFRAL
iHOPGFRAL
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Mon Jul 30 13:47:12 CEST 2018

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