GFUS (GDP-L-fucose synthase)

2012-09-01  

Identity

HGNC
LOCATION
8q24.3
LOCUSID
ALIAS
FX,P35B,SDR4E1,TSTA3
FUSION GENES

Other Information

Locus ID:

NCBI: 7264
MIM: 137020
HGNC: 12390
Ensembl: ENSG00000104522

Variants:

dbSNP: 7264
ClinVar: 7264
TCGA: ENSG00000104522
COSMIC: GFUS

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000104522ENST00000425753Q13630
ENSG00000104522ENST00000425753A0A140VKC8
ENSG00000104522ENST00000524719H0YCP7
ENSG00000104522ENST00000526290E9PLH9
ENSG00000104522ENST00000527006H0YE90
ENSG00000104522ENST00000529048E9PKL9
ENSG00000104522ENST00000529064Q13630
ENSG00000104522ENST00000529064A0A140VKC8
ENSG00000104522ENST00000530474E9PP60
ENSG00000104522ENST00000533817E9PP14

Pathways

PathwaySourceExternal ID
Fructose and mannose metabolismKEGGko00051
Amino sugar and nucleotide sugar metabolismKEGGko00520
Fructose and mannose metabolismKEGGhsa00051
Amino sugar and nucleotide sugar metabolismKEGGhsa00520
Metabolic pathwaysKEGGhsa01100
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
Asparagine N-linked glycosylationREACTOMER-HSA-446203
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent proteinREACTOMER-HSA-446193
Synthesis of substrates in N-glycan biosythesisREACTOMER-HSA-446219
GDP-fucose biosynthesisREACTOMER-HSA-6787639

References

Pubmed IDYearTitleCitations
265317222016Oncogenic potential of TSTA3 in breast cancer and its regulation by the tumor suppressors miR-125a-5p and miR-125b.14
225281252012Tissue-specific transplantation antigen P35B (TSTA3) immune response-mediated metabolism coupling cell cycle to postreplication repair network in no-tumor hepatitis/cirrhotic tissues (HBV or HCV infection) by biocomputation.10
237745042013The crystal structure of human GDP-L-fucose synthase.2
299501512018High TSTA3 Expression as a Candidate Biomarker for Poor Prognosis of Patients With ESCC.0

Citation

Dessen P

GFUS (GDP-L-fucose synthase)

Atlas Genet Cytogenet Oncol Haematol. 2012-09-01

Online version: http://atlasgeneticsoncology.org/gene/52892/gfus