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GGA2 (golgi associated, gamma adaptin ear containing, ARF binding protein 2)

Identity

Alias (NCBI)VEAR
HGNC (Hugo) GGA2
HGNC Alias symbVEAR
KIAA1080
HGNC Previous namegolgi-associated, gamma adaptin ear containing, ARF binding protein 2
LocusID (NCBI) 23062
Atlas_Id 57890
Location 16p12.2  [Link to chromosome band 16p12]
Location_base_pair Starts at 23463542 and ends at 23510494 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
GGA2 (16p12.2) / NUCKS1 (1q32.1)GGA2 (16p12.2) / PRKCB (16p12.2)GGA2 (16p12.2) / RPF1 (1p22.3)
MAPK8IP3 (16p13.3) / GGA2 (16p12.2)NDUFS6 (5p15.33) / GGA2 (16p12.2)SEZ6L (22q12.1) / GGA2 (16p12.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)GGA2   16064
Cards
Entrez_Gene (NCBI)GGA2    golgi associated, gamma adaptin ear containing, ARF binding protein 2
AliasesVEAR
GeneCards (Weizmann)GGA2
Ensembl hg19 (Hinxton)ENSG00000103365 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000103365 [Gene_View]  ENSG00000103365 [Sequence]  chr16:23463542-23510494 [Contig_View]  GGA2 [Vega]
ICGC DataPortalENSG00000103365
TCGA cBioPortalGGA2
AceView (NCBI)GGA2
Genatlas (Paris)GGA2
SOURCE (Princeton)GGA2
Genetics Home Reference (NIH)GGA2
Genomic and cartography
GoldenPath hg38 (UCSC)GGA2  -     chr16:23463542-23510494 -  16p12.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GGA2  -     16p12.2   [Description]    (hg19-Feb_2009)
GoldenPathGGA2 - 16p12.2 [CytoView hg19]  GGA2 - 16p12.2 [CytoView hg38]
ImmunoBaseENSG00000103365
Genome Data Viewer NCBIGGA2 [Mapview hg19]  
OMIM606005   
Gene and transcription
Genbank (Entrez)AB029003 AF165531 AF190863 AF233522 AF323754
RefSeq transcript (Entrez)NM_015044
Consensus coding sequences : CCDS (NCBI)GGA2
Gene ExpressionGGA2 [ NCBI-GEO ]   GGA2 [ EBI - ARRAY_EXPRESS ]   GGA2 [ SEEK ]   GGA2 [ MEM ]
Gene Expression Viewer (FireBrowse)GGA2 [ Firebrowse - Broad ]
GenevisibleExpression of GGA2 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23062
GTEX Portal (Tissue expression)GGA2
Human Protein AtlasENSG00000103365-GGA2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UJY4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UJY4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UJY4
PhosPhoSitePlusQ9UJY4
Domaine pattern : Prosite (Expaxy)GAE (PS50180)    GAT (PS50909)    VHS (PS50179)   
Domains : Interpro (EBI)Clathrin_a/b/g-adaptin_app_Ig    Clathrin_app_Ig-like_sf    ENTH_VHS    GAE_dom    GAT_dom    GAT_sf    GGA_N-GAT    VHS_dom   
Domain families : Pfam (Sanger)Alpha_adaptinC2 (PF02883)    GAT (PF03127)    GGA_N-GAT (PF18308)    VHS (PF00790)   
Domain families : Pfam (NCBI)pfam02883    pfam03127    pfam18308    pfam00790   
Domain families : Smart (EMBL)Alpha_adaptinC2 (SM00809)  VHS (SM00288)  
Conserved Domain (NCBI)GGA2
PDB (RSDB)1MHQ   
PDB Europe1MHQ   
PDB (PDBSum)1MHQ   
PDB (IMB)1MHQ   
Structural Biology KnowledgeBase1MHQ   
SCOP (Structural Classification of Proteins)1MHQ   
CATH (Classification of proteins structures)1MHQ   
SuperfamilyQ9UJY4
AlphaFold pdb e-kbQ9UJY4   
Human Protein Atlas [tissue]ENSG00000103365-GGA2 [tissue]
Protein Interaction databases
DIP (DOE-UCLA)Q9UJY4
IntAct (EBI)Q9UJY4
BioGRIDGGA2
STRING (EMBL)GGA2
ZODIACGGA2
Ontologies - Pathways
QuickGOQ9UJY4
Ontology : AmiGOprotein binding  Golgi apparatus  trans-Golgi network  intracellular protein transport  endosome membrane  clathrin-coated vesicle  small GTPase binding  early endosome membrane  protein localization to cell surface  phosphatidylinositol binding  Golgi to plasma membrane protein transport  ubiquitin binding  amyloid fibril formation  
Ontology : EGO-EBIprotein binding  Golgi apparatus  trans-Golgi network  intracellular protein transport  endosome membrane  clathrin-coated vesicle  small GTPase binding  early endosome membrane  protein localization to cell surface  phosphatidylinositol binding  Golgi to plasma membrane protein transport  ubiquitin binding  amyloid fibril formation  
Pathways : KEGGLysosome   
NDEx NetworkGGA2
Atlas of Cancer Signalling NetworkGGA2
Wikipedia pathwaysGGA2
Orthology - Evolution
OrthoDB23062
GeneTree (enSembl)ENSG00000103365
Phylogenetic Trees/Animal Genes : TreeFamGGA2
Homologs : HomoloGeneGGA2
Homology/Alignments : Family Browser (UCSC)GGA2
Gene fusions - Rearrangements
Fusion : QuiverGGA2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGGA2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GGA2
dbVarGGA2
ClinVarGGA2
MonarchGGA2
1000_GenomesGGA2 
Exome Variant ServerGGA2
GNOMAD BrowserENSG00000103365
Varsome BrowserGGA2
ACMGGGA2 variants
VarityQ9UJY4
Genomic Variants (DGV)GGA2 [DGVbeta]
DECIPHERGGA2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGGA2 
Mutations
ICGC Data PortalGGA2 
TCGA Data PortalGGA2 
Broad Tumor PortalGGA2
OASIS PortalGGA2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGGA2  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DGGA2
Mutations and Diseases : HGMDGGA2
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaGGA2
DgiDB (Drug Gene Interaction Database)GGA2
DoCM (Curated mutations)GGA2
CIViC (Clinical Interpretations of Variants in Cancer)GGA2
Cancer3DGGA2
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606005   
Orphanet
DisGeNETGGA2
MedgenGGA2
Genetic Testing Registry GGA2
NextProtQ9UJY4 [Medical]
GENETestsGGA2
Target ValidationGGA2
Huge Navigator GGA2 [HugePedia]
ClinGenGGA2
Clinical trials, drugs, therapy
MyCancerGenomeGGA2
Protein Interactions : CTDGGA2
Pharm GKB GenePA28658
PharosQ9UJY4
Clinical trialGGA2
Miscellaneous
canSAR (ICR)GGA2
HarmonizomeGGA2
DataMed IndexGGA2
Probes
Litterature
PubMed79 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXGGA2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:10:40 CEST 2021

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