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GGA2 (golgi associated, gamma adaptin ear containing, ARF binding protein 2)

Identity

Alias_namesgolgi-associated, gamma adaptin ear containing, ARF binding protein 2
Alias_symbol (synonym)VEAR
KIAA1080
Other alias
HGNC (Hugo) GGA2
LocusID (NCBI) 23062
Atlas_Id 63764
Location 16p12.2  [Link to chromosome band 16p12]
Location_base_pair Starts at 23463542 and ends at 23510494 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
GGA2 (16p12.2) / NUCKS1 (1q32.1)GGA2 (16p12.2) / PRKCB (16p12.2)GGA2 (16p12.2) / RPF1 (1p22.3)
MAPK8IP3 (16p13.3) / GGA2 (16p12.2)NDUFS6 (5p15.33) / GGA2 (16p12.2)SEZ6L (22q12.1) / GGA2 (16p12.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GGA2   16064
Cards
Entrez_Gene (NCBI)GGA2  23062  golgi associated, gamma adaptin ear containing, ARF binding protein 2
AliasesVEAR
GeneCards (Weizmann)GGA2
Ensembl hg19 (Hinxton)ENSG00000103365 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000103365 [Gene_View]  chr16:23463542-23510494 [Contig_View]  GGA2 [Vega]
ICGC DataPortalENSG00000103365
TCGA cBioPortalGGA2
AceView (NCBI)GGA2
Genatlas (Paris)GGA2
WikiGenes23062
SOURCE (Princeton)GGA2
Genetics Home Reference (NIH)GGA2
Genomic and cartography
GoldenPath hg38 (UCSC)GGA2  -     chr16:23463542-23510494 -  16p12.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GGA2  -     16p12.2   [Description]    (hg19-Feb_2009)
EnsemblGGA2 - 16p12.2 [CytoView hg19]  GGA2 - 16p12.2 [CytoView hg38]
Mapping of homologs : NCBIGGA2 [Mapview hg19]  GGA2 [Mapview hg38]
OMIM606005   
Gene and transcription
Genbank (Entrez)AB029003 AF165531 AF190863 AF233522 AF323754
RefSeq transcript (Entrez)NM_015044
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GGA2
Cluster EST : UnigeneHs.460336 [ NCBI ]
CGAP (NCI)Hs.460336
Alternative Splicing GalleryENSG00000103365
Gene ExpressionGGA2 [ NCBI-GEO ]   GGA2 [ EBI - ARRAY_EXPRESS ]   GGA2 [ SEEK ]   GGA2 [ MEM ]
Gene Expression Viewer (FireBrowse)GGA2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23062
GTEX Portal (Tissue expression)GGA2
Human Protein AtlasENSG00000103365-GGA2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UJY4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UJY4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UJY4
Splice isoforms : SwissVarQ9UJY4
PhosPhoSitePlusQ9UJY4
Domaine pattern : Prosite (Expaxy)GAE (PS50180)    GAT (PS50909)    VHS (PS50179)   
Domains : Interpro (EBI)Clathrin_a/b/g-adaptin_app_Ig    Clathrin_g-adaptin_app    Coatomer/clathrin_app_Ig-like    ENTH_VHS    GAT_dom    VHS_dom   
Domain families : Pfam (Sanger)Alpha_adaptinC2 (PF02883)    GAT (PF03127)    VHS (PF00790)   
Domain families : Pfam (NCBI)pfam02883    pfam03127    pfam00790   
Domain families : Smart (EMBL)Alpha_adaptinC2 (SM00809)  VHS (SM00288)  
Conserved Domain (NCBI)GGA2
DMDM Disease mutations23062
Blocks (Seattle)GGA2
PDB (SRS)1MHQ   
PDB (PDBSum)1MHQ   
PDB (IMB)1MHQ   
PDB (RSDB)1MHQ   
Structural Biology KnowledgeBase1MHQ   
SCOP (Structural Classification of Proteins)1MHQ   
CATH (Classification of proteins structures)1MHQ   
SuperfamilyQ9UJY4
Human Protein Atlas [tissue]ENSG00000103365-GGA2 [tissue]
Peptide AtlasQ9UJY4
HPRD09347
IPIIPI00296772   IPI00442454   IPI00976135   
Protein Interaction databases
DIP (DOE-UCLA)Q9UJY4
IntAct (EBI)Q9UJY4
FunCoupENSG00000103365
BioGRIDGGA2
STRING (EMBL)GGA2
ZODIACGGA2
Ontologies - Pathways
QuickGOQ9UJY4
Ontology : AmiGOprotein binding  Golgi apparatus  trans-Golgi network  intracellular protein transport  endosome membrane  vesicle-mediated transport  clathrin adaptor complex  clathrin-coated vesicle  ADP-ribosylation factor binding  early endosome membrane  cellular protein metabolic process  membrane organization  
Ontology : EGO-EBIprotein binding  Golgi apparatus  trans-Golgi network  intracellular protein transport  endosome membrane  vesicle-mediated transport  clathrin adaptor complex  clathrin-coated vesicle  ADP-ribosylation factor binding  early endosome membrane  cellular protein metabolic process  membrane organization  
Pathways : KEGGLysosome   
NDEx NetworkGGA2
Atlas of Cancer Signalling NetworkGGA2
Wikipedia pathwaysGGA2
Orthology - Evolution
OrthoDB23062
GeneTree (enSembl)ENSG00000103365
Phylogenetic Trees/Animal Genes : TreeFamGGA2
HOVERGENQ9UJY4
HOGENOMQ9UJY4
Homologs : HomoloGeneGGA2
Homology/Alignments : Family Browser (UCSC)GGA2
Gene fusions - Rearrangements
Tumor Fusion PortalGGA2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGGA2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GGA2
dbVarGGA2
ClinVarGGA2
1000_GenomesGGA2 
Exome Variant ServerGGA2
ExAC (Exome Aggregation Consortium)ENSG00000103365
GNOMAD BrowserENSG00000103365
Genetic variants : HAPMAP23062
Genomic Variants (DGV)GGA2 [DGVbeta]
DECIPHERGGA2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGGA2 
Mutations
ICGC Data PortalGGA2 
TCGA Data PortalGGA2 
Broad Tumor PortalGGA2
OASIS PortalGGA2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGGA2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGGA2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GGA2
DgiDB (Drug Gene Interaction Database)GGA2
DoCM (Curated mutations)GGA2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GGA2 (select a term)
intoGenGGA2
Cancer3DGGA2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606005   
Orphanet
DisGeNETGGA2
MedgenGGA2
Genetic Testing Registry GGA2
NextProtQ9UJY4 [Medical]
TSGene23062
GENETestsGGA2
Target ValidationGGA2
Huge Navigator GGA2 [HugePedia]
snp3D : Map Gene to Disease23062
BioCentury BCIQGGA2
ClinGenGGA2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD23062
Chemical/Pharm GKB GenePA28658
Clinical trialGGA2
Miscellaneous
canSAR (ICR)GGA2 (select the gene name)
Probes
Litterature
PubMed64 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGGA2
EVEXGGA2
GoPubMedGGA2
iHOPGGA2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 13:33:17 CET 2017

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