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GGA3 (golgi associated, gamma adaptin ear containing, ARF binding protein 3)

Identity

Alias_namesgolgi-associated, gamma adaptin ear containing, ARF binding protein 3
Alias_symbol (synonym)KIAA0154
Other alias-
HGNC (Hugo) GGA3
LocusID (NCBI) 23163
Atlas_Id 63765
Location 17q25.1  [Link to chromosome band 17q25]
Location_base_pair Starts at 75236592 and ends at 75262393 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
AKAP1 (17q22) / GGA3 (17q25.1)GGA3 (17q25.1) / ATF7 (12q13.13)HN1 (17q25.1) / GGA3 (17q25.1)
MRPS7 (17q25.1) / GGA3 (17q25.1)NRDE2 (14q32.11) / GGA3 (17q25.1)AKAP1 GGA3
HN1 GGA3MRPS7 GGA3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GGA3   17079
Cards
Entrez_Gene (NCBI)GGA3  23163  golgi associated, gamma adaptin ear containing, ARF binding protein 3
Aliases
GeneCards (Weizmann)GGA3
Ensembl hg19 (Hinxton)ENSG00000125447 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000125447 [Gene_View]  chr17:75236592-75262393 [Contig_View]  GGA3 [Vega]
ICGC DataPortalENSG00000125447
TCGA cBioPortalGGA3
AceView (NCBI)GGA3
Genatlas (Paris)GGA3
WikiGenes23163
SOURCE (Princeton)GGA3
Genetics Home Reference (NIH)GGA3
Genomic and cartography
GoldenPath hg38 (UCSC)GGA3  -     chr17:75236592-75262393 -  17q25.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GGA3  -     17q25.1   [Description]    (hg19-Feb_2009)
EnsemblGGA3 - 17q25.1 [CytoView hg19]  GGA3 - 17q25.1 [CytoView hg38]
Mapping of homologs : NCBIGGA3 [Mapview hg19]  GGA3 [Mapview hg38]
OMIM606006   
Gene and transcription
Genbank (Entrez)AF190864 AF219138 AF219139 AK124541 AK291651
RefSeq transcript (Entrez)NM_001172703 NM_001172704 NM_001291641 NM_001291642 NM_014001 NM_138619
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GGA3
Cluster EST : UnigeneHs.87726 [ NCBI ]
CGAP (NCI)Hs.87726
Alternative Splicing GalleryENSG00000125447
Gene ExpressionGGA3 [ NCBI-GEO ]   GGA3 [ EBI - ARRAY_EXPRESS ]   GGA3 [ SEEK ]   GGA3 [ MEM ]
Gene Expression Viewer (FireBrowse)GGA3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23163
GTEX Portal (Tissue expression)GGA3
Human Protein AtlasENSG00000125447-GGA3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NZ52   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NZ52  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NZ52
Splice isoforms : SwissVarQ9NZ52
PhosPhoSitePlusQ9NZ52
Domaine pattern : Prosite (Expaxy)GAE (PS50180)    GAT (PS50909)    VHS (PS50179)   
Domains : Interpro (EBI)Clathrin_a/b/g-adaptin_app_Ig    Clathrin_g-adaptin_app    Coatomer/clathrin_app_Ig-like    ENTH_VHS    GAT_dom    GGA3    VHS_dom   
Domain families : Pfam (Sanger)Alpha_adaptinC2 (PF02883)    GAT (PF03127)    VHS (PF00790)   
Domain families : Pfam (NCBI)pfam02883    pfam03127    pfam00790   
Domain families : Smart (EMBL)Alpha_adaptinC2 (SM00809)  VHS (SM00288)  
Conserved Domain (NCBI)GGA3
DMDM Disease mutations23163
Blocks (Seattle)GGA3
PDB (SRS)1JPL    1JUQ    1LF8    1P4U    1WR6    1YD8   
PDB (PDBSum)1JPL    1JUQ    1LF8    1P4U    1WR6    1YD8   
PDB (IMB)1JPL    1JUQ    1LF8    1P4U    1WR6    1YD8   
PDB (RSDB)1JPL    1JUQ    1LF8    1P4U    1WR6    1YD8   
Structural Biology KnowledgeBase1JPL    1JUQ    1LF8    1P4U    1WR6    1YD8   
SCOP (Structural Classification of Proteins)1JPL    1JUQ    1LF8    1P4U    1WR6    1YD8   
CATH (Classification of proteins structures)1JPL    1JUQ    1LF8    1P4U    1WR6    1YD8   
SuperfamilyQ9NZ52
Human Protein Atlas [tissue]ENSG00000125447-GGA3 [tissue]
Peptide AtlasQ9NZ52
HPRD10443
IPIIPI00021174   IPI00219305   IPI00922831   IPI00955894   IPI00922611   IPI00955855   
Protein Interaction databases
DIP (DOE-UCLA)Q9NZ52
IntAct (EBI)Q9NZ52
FunCoupENSG00000125447
BioGRIDGGA3
STRING (EMBL)GGA3
ZODIACGGA3
Ontologies - Pathways
QuickGOQ9NZ52
Ontology : AmiGOprotein binding  Golgi apparatus  trans-Golgi network  intracellular protein transport  endosome membrane  vesicle-mediated transport  clathrin adaptor complex  ADP-ribosylation factor binding  early endosome membrane  cellular protein metabolic process  positive regulation of protein catabolic process  recycling endosome membrane  membrane organization  
Ontology : EGO-EBIprotein binding  Golgi apparatus  trans-Golgi network  intracellular protein transport  endosome membrane  vesicle-mediated transport  clathrin adaptor complex  ADP-ribosylation factor binding  early endosome membrane  cellular protein metabolic process  positive regulation of protein catabolic process  recycling endosome membrane  membrane organization  
Pathways : KEGGLysosome   
NDEx NetworkGGA3
Atlas of Cancer Signalling NetworkGGA3
Wikipedia pathwaysGGA3
Orthology - Evolution
OrthoDB23163
GeneTree (enSembl)ENSG00000125447
Phylogenetic Trees/Animal Genes : TreeFamGGA3
HOVERGENQ9NZ52
HOGENOMQ9NZ52
Homologs : HomoloGeneGGA3
Homology/Alignments : Family Browser (UCSC)GGA3
Gene fusions - Rearrangements
Fusion: TCGA_MDACCAKAP1 GGA3
Fusion: TCGA_MDACCHN1 GGA3
Fusion: TCGA_MDACCMRPS7 GGA3
Tumor Fusion PortalGGA3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGGA3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GGA3
dbVarGGA3
ClinVarGGA3
1000_GenomesGGA3 
Exome Variant ServerGGA3
ExAC (Exome Aggregation Consortium)ENSG00000125447
GNOMAD BrowserENSG00000125447
Genetic variants : HAPMAP23163
Genomic Variants (DGV)GGA3 [DGVbeta]
DECIPHERGGA3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGGA3 
Mutations
ICGC Data PortalGGA3 
TCGA Data PortalGGA3 
Broad Tumor PortalGGA3
OASIS PortalGGA3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGGA3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGGA3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GGA3
DgiDB (Drug Gene Interaction Database)GGA3
DoCM (Curated mutations)GGA3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GGA3 (select a term)
intoGenGGA3
Cancer3DGGA3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606006   
Orphanet
DisGeNETGGA3
MedgenGGA3
Genetic Testing Registry GGA3
NextProtQ9NZ52 [Medical]
TSGene23163
GENETestsGGA3
Target ValidationGGA3
Huge Navigator GGA3 [HugePedia]
snp3D : Map Gene to Disease23163
BioCentury BCIQGGA3
ClinGenGGA3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD23163
Chemical/Pharm GKB GenePA28659
Clinical trialGGA3
Miscellaneous
canSAR (ICR)GGA3 (select the gene name)
Probes
Litterature
PubMed68 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGGA3
EVEXGGA3
GoPubMedGGA3
iHOPGGA3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 13:35:25 CET 2017

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