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GGCT (gamma-glutamylcyclotransferase)

Identity

Alias_namesC7orf24
GCTG
chromosome 7 open reading frame 24
Alias_symbol (synonym)MGC3077
CRF21
Ggc
Other aliasGGC
HGNC (Hugo) GGCT
LocusID (NCBI) 79017
Atlas_Id 47695
Location 7p14.3  [Link to chromosome band 7p14]
Location_base_pair Starts at 30536237 and ends at 30544457 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
AGT (1q42.2) / GGCT (7p14.3)COL26A1 (7q22.1) / GGCT (7p14.3)GGCT (7p14.3) / GGCT (7p14.3)
GGCT (7p14.3) / PLPP1 (5q11.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GGCT   21705
Cards
Entrez_Gene (NCBI)GGCT  79017  gamma-glutamylcyclotransferase
AliasesC7orf24; CRF21; GCTG; GGC
GeneCards (Weizmann)GGCT
Ensembl hg19 (Hinxton)ENSG00000006625 [Gene_View]  chr7:30536237-30544457 [Contig_View]  GGCT [Vega]
Ensembl hg38 (Hinxton)ENSG00000006625 [Gene_View]  chr7:30536237-30544457 [Contig_View]  GGCT [Vega]
ICGC DataPortalENSG00000006625
TCGA cBioPortalGGCT
AceView (NCBI)GGCT
Genatlas (Paris)GGCT
WikiGenes79017
SOURCE (Princeton)GGCT
Genetics Home Reference (NIH)GGCT
Genomic and cartography
GoldenPath hg19 (UCSC)GGCT  -     chr7:30536237-30544457 -  7p14.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)GGCT  -     7p14.3   [Description]    (hg38-Dec_2013)
EnsemblGGCT - 7p14.3 [CytoView hg19]  GGCT - 7p14.3 [CytoView hg38]
Mapping of homologs : NCBIGGCT [Mapview hg19]  GGCT [Mapview hg38]
OMIM137170   
Gene and transcription
Genbank (Entrez)AK021779 AK315608 BC000625 BC005356 BC013937
RefSeq transcript (Entrez)NM_001199815 NM_001199816 NM_001199817 NM_024051
RefSeq genomic (Entrez)NC_000007 NC_018918 NT_007819 NW_004929329
Consensus coding sequences : CCDS (NCBI)GGCT
Cluster EST : UnigeneHs.530024 [ NCBI ]
CGAP (NCI)Hs.530024
Alternative Splicing GalleryENSG00000006625
Gene ExpressionGGCT [ NCBI-GEO ]   GGCT [ EBI - ARRAY_EXPRESS ]   GGCT [ SEEK ]   GGCT [ MEM ]
Gene Expression Viewer (FireBrowse)GGCT [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)79017
GTEX Portal (Tissue expression)GGCT
Protein : pattern, domain, 3D structure
UniProt/SwissProtO75223   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO75223  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO75223
Splice isoforms : SwissVarO75223
Catalytic activity : Enzyme2.3.2.4 [ Enzyme-Expasy ]   2.3.2.42.3.2.4 [ IntEnz-EBI ]   2.3.2.4 [ BRENDA ]   2.3.2.4 [ KEGG ]   
PhosPhoSitePlusO75223
Domains : Interpro (EBI)Butirosin_synth_BtrG-like    G-Glutamylcylcotransferase   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)GGCT
DMDM Disease mutations79017
Blocks (Seattle)GGCT
PDB (SRS)2I5T    2PN7    2Q53    2RBH    3CRY   
PDB (PDBSum)2I5T    2PN7    2Q53    2RBH    3CRY   
PDB (IMB)2I5T    2PN7    2Q53    2RBH    3CRY   
PDB (RSDB)2I5T    2PN7    2Q53    2RBH    3CRY   
Structural Biology KnowledgeBase2I5T    2PN7    2Q53    2RBH    3CRY   
SCOP (Structural Classification of Proteins)2I5T    2PN7    2Q53    2RBH    3CRY   
CATH (Classification of proteins structures)2I5T    2PN7    2Q53    2RBH    3CRY   
SuperfamilyO75223
Human Protein AtlasENSG00000006625
Peptide AtlasO75223
HPRD12912
IPIIPI00031564   IPI00020301   IPI00903238   IPI00916717   IPI00916612   IPI00976223   IPI00917449   IPI00917299   
Protein Interaction databases
DIP (DOE-UCLA)O75223
IntAct (EBI)O75223
FunCoupENSG00000006625
BioGRIDGGCT
STRING (EMBL)GGCT
ZODIACGGCT
Ontologies - Pathways
QuickGOO75223
Ontology : AmiGOrelease of cytochrome c from mitochondria  gamma-glutamylcyclotransferase activity  gamma-glutamylcyclotransferase activity  cytosol  cytosol  glutathione biosynthetic process  protein homodimerization activity  extracellular exosome  
Ontology : EGO-EBIrelease of cytochrome c from mitochondria  gamma-glutamylcyclotransferase activity  gamma-glutamylcyclotransferase activity  cytosol  cytosol  glutathione biosynthetic process  protein homodimerization activity  extracellular exosome  
Pathways : KEGGGlutathione metabolism   
NDEx NetworkGGCT
Atlas of Cancer Signalling NetworkGGCT
Wikipedia pathwaysGGCT
Orthology - Evolution
OrthoDB79017
GeneTree (enSembl)ENSG00000006625
Phylogenetic Trees/Animal Genes : TreeFamGGCT
HOVERGENO75223
HOGENOMO75223
Homologs : HomoloGeneGGCT
Homology/Alignments : Family Browser (UCSC)GGCT
Gene fusions - Rearrangements
Fusion : MitelmanCOL26A1/GGCT [7q22.1/7p14.3]  [t(7;7)(p14;q22)]  
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGGCT [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GGCT
dbVarGGCT
ClinVarGGCT
1000_GenomesGGCT 
Exome Variant ServerGGCT
ExAC (Exome Aggregation Consortium)GGCT (select the gene name)
Genetic variants : HAPMAP79017
Genomic Variants (DGV)GGCT [DGVbeta]
DECIPHER (Syndromes)7:30536237-30544457  ENSG00000006625
CONAN: Copy Number AnalysisGGCT 
Mutations
ICGC Data PortalGGCT 
TCGA Data PortalGGCT 
Broad Tumor PortalGGCT
OASIS PortalGGCT [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGGCT  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGGCT
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GGCT
DgiDB (Drug Gene Interaction Database)GGCT
DoCM (Curated mutations)GGCT (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GGCT (select a term)
intoGenGGCT
Cancer3DGGCT(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM137170   
Orphanet
MedgenGGCT
Genetic Testing Registry GGCT
NextProtO75223 [Medical]
TSGene79017
GENETestsGGCT
Huge Navigator GGCT [HugePedia]
snp3D : Map Gene to Disease79017
BioCentury BCIQGGCT
ClinGenGGCT
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD79017
Chemical/Pharm GKB GenePA162389392
Clinical trialGGCT
Miscellaneous
canSAR (ICR)GGCT (select the gene name)
Probes
Litterature
PubMed30 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGGCT
EVEXGGCT
GoPubMedGGCT
iHOPGGCT
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Mar 14 13:07:21 CET 2017

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