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GGT1 (gamma-glutamyltransferase 1)

Identity

Other namesCD224
D22S672
D22S732
GGT
GGT 1
GTG
HGNC (Hugo) GGT1
LocusID (NCBI) 2678
Location 22q11.23
Location_base_pair Starts at 24999124 and ends at 25024972 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)GGT1   4250
Entrez_Gene (NCBI)GGT1  2678  gamma-glutamyltransferase 1
Cards
GeneCards (Weizmann)GGT1
Ensembl (Hinxton)ENSG00000100031 [Gene_View]  chr22:24999124-25024972 [Contig_View]  GGT1 [Vega]
AceView (NCBI)GGT1
Genatlas (Paris)GGT1
SOURCE (Stanford)NM_001032364 NM_001032365 NM_005265 NM_013430
Genomic and cartography
GoldenPath (UCSC)GGT1  -  22q11.23   chr22:24999124-25024972 +  22q11.23   [Description]    (hg19-Feb_2009)
EnsemblGGT1 - 22q11.23 [CytoView]
Mapping of homologs : NCBIGGT1 [Mapview]
OMIM231950   612346   612365   612366   
Gene and transcription
Genbank (Entrez)AL832738 AU077341 BC025927 BC035341 BC065921
RefSeq transcript (SRS)NM_001032364 NM_001032365 NM_005265 NM_013430
RefSeq transcript (Entrez)NM_001032364 NM_001032365 NM_005265 NM_013430
RefSeq genomic (SRS)AC_000154 NC_000022 NC_018933 NG_008111 NT_011520 NW_001838745 NW_004078112
RefSeq genomic (Entrez)AC_000154 NC_000022 NC_018933 NG_008111 NT_011520 NW_001838745 NW_004078112
Consensus coding sequences : CCDS (NCBI)GGT1
Cluster EST : UnigeneHs.645535 [ SRS ] Hs.645535 [ NCBI ]
CGAP (NCI)Hs.645535
Alternative Splicing : Fast-db (Paris)GSHG0019897
Alternative Splicing GalleryENSG00000100031
Gene ExpressionGGT1 [ NCBI-GEO ]   GGT1 [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP19440 (SRS) P19440 (Uniprot)
NextProtP19440
With graphics : InterProP19440
Splice isoforms : SwissVarP19440(Swissvar)
Domaine pattern : Prosite (SRS)G_GLU_TRANSPEPTIDASE (PS00462)   
Domaine pattern : Prosite (Expaxy)G_GLU_TRANSPEPTIDASE (PS00462)   
Domains : Interpro (SRS)GGT_peptidase   
Domains : Interpro (EBI)GGT_peptidase   
Related proteins : CluSTrP19440
Domain families : Pfam (SRS)G_glu_transpept (PF01019)   
Domain families : Pfam (Sanger)G_glu_transpept (PF01019)   
Domain families : Pfam (NCBI)pfam01019   
DMDM2678
Blocks (Seattle)P19440
Human Protein AtlasENSG00000100031
HPRD01980
IPIIPI00018901   IPI00217717   IPI00339263   IPI00816658   IPI00879909   IPI00878847   IPI00878679   IPI00878471   IPI00878307   IPI00879474   IPI00879296   IPI00879120   IPI00878032   IPI00880077   IPI00879902   IPI00879740   IPI00879725   IPI00878222   IPI00877874   
Protein Interaction databases
DIP (DOE-UCLA)P19440
IntAct (EBI)P19440
FunCoupENSG00000100031
REACTOMEGGT1
Protein Interaction Database2678
BioGRIDGGT1
InParanoidP19440
Interologous Interaction database P19440
IntegromeDBGGT1
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)GGT1
SNP (GeneSNP Utah)GGT1
SNP : HGBaseGGT1
Genetic variants : HAPMAPGGT1
Somatic Mutations in Cancer : COSMICGGT1 
CONAN: Copy Number AnalysisGGT1 
Mutations and Diseases : HGMDGGT1
OMIM231950    612346    612365    612366   
GENETests231950    612346    612365    612366   
Disease Genetic AssociationGGT1
Huge Navigator GGT1 [HugePedia]  GGT1 [HugeCancerGEM]
Genomic VariantsGGT1  GGT1 [DGVbeta]
ClinVarGGT1
snp3D : Map Gene to Disease2678
General knowledge
Homologs : HomoloGeneGGT1
Homology/Alignments : Family Browser (UCSC)GGT1
Phylogenetic Trees/Animal Genes : TreeFamGGT1
Catalytic activity : Enzyme2.3.2.2 [ Enzyme-Expasy ]   2.3.2.2 [ Enzyme-SRS ]   2.3.2.2 [ IntEnz-EBI ]   2.3.2.2 [ BRENDA ]   2.3.2.2 [ KEGG ]   
Chemical/Protein Interactions : CTD2678
Chemical/Pharm GKB GenePA28662
Clinical trialGGT1
Cancer Resource (Charite)ENSG00000100031
Ontology : AmiGOregulation of immune system process  gamma-glutamyltransferase activity  gamma-glutamyltransferase activity  protein binding  plasma membrane  cellular amino acid metabolic process  leukotriene metabolic process  glutathione metabolic process  glutathione biosynthetic process  glutathione biosynthetic process  xenobiotic metabolic process  spermatogenesis  membrane  integral to membrane  hydrolase activity  cysteine biosynthetic process  arachidonic acid metabolic process  leukotriene biosynthetic process  anchored to external side of plasma membrane  small molecule metabolic process  regulation of inflammatory response  
Ontology : EGO-EBIregulation of immune system process  gamma-glutamyltransferase activity  gamma-glutamyltransferase activity  protein binding  plasma membrane  cellular amino acid metabolic process  leukotriene metabolic process  glutathione metabolic process  glutathione biosynthetic process  glutathione biosynthetic process  xenobiotic metabolic process  spermatogenesis  membrane  integral to membrane  hydrolase activity  cysteine biosynthetic process  arachidonic acid metabolic process  leukotriene biosynthetic process  anchored to external side of plasma membrane  small molecule metabolic process  regulation of inflammatory response  
Pathways : KEGGCyanoamino acid metabolismSelenoamino acid metabolismTaurine and hypotaurine metabolismArachidonic acid metabolismGlutathione metabolism
Other databases
Probes
Litterature
PubMed109 Pubmed reference(s) in Entrez
PubGeneGGT1
iHOPGGT1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Jun 14 17:45:27 CEST 2013
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