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GGT1 (gamma-glutamyltransferase 1)

Identity

Alias_namesGGT
Alias_symbol (synonym)D22S672
D22S732
CD224
Other aliasGGT 1
GTG
HGNC (Hugo) GGT1
LocusID (NCBI) 2678
Atlas_Id 40709
Location 22q11.23  [Link to chromosome band 22q11]
Location_base_pair Starts at 24603157 and ends at 24629005 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
GGT1 (22q11.23) / CARS2 (13q34)IGSF3 (1p13.1) / GGT1 (22q11.23)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GGT1   4250
Cards
Entrez_Gene (NCBI)GGT1  2678  gamma-glutamyltransferase 1
AliasesCD224; D22S672; D22S732; GGT; 
GGT; GTG
GeneCards (Weizmann)GGT1
Ensembl hg19 (Hinxton)ENSG00000100031 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000100031 [Gene_View]  chr22:24603157-24629005 [Contig_View]  GGT1 [Vega]
ICGC DataPortalENSG00000100031
TCGA cBioPortalGGT1
AceView (NCBI)GGT1
Genatlas (Paris)GGT1
WikiGenes2678
SOURCE (Princeton)GGT1
Genetics Home Reference (NIH)GGT1
Genomic and cartography
GoldenPath hg38 (UCSC)GGT1  -     chr22:24603157-24629005 +  22q11.23   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GGT1  -     22q11.23   [Description]    (hg19-Feb_2009)
EnsemblGGT1 - 22q11.23 [CytoView hg19]  GGT1 - 22q11.23 [CytoView hg38]
Mapping of homologs : NCBIGGT1 [Mapview hg19]  GGT1 [Mapview hg38]
OMIM612346   
Gene and transcription
Genbank (Entrez)###############################################################################################################################################################################################################################################################
RefSeq transcript (Entrez)NM_001032364 NM_001032365 NM_001288833 NM_005265 NM_013421 NM_013430
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GGT1
Cluster EST : UnigeneHs.645535 [ NCBI ]
CGAP (NCI)Hs.645535
Alternative Splicing GalleryENSG00000100031
Gene ExpressionGGT1 [ NCBI-GEO ]   GGT1 [ EBI - ARRAY_EXPRESS ]   GGT1 [ SEEK ]   GGT1 [ MEM ]
Gene Expression Viewer (FireBrowse)GGT1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2678
GTEX Portal (Tissue expression)GGT1
Protein : pattern, domain, 3D structure
UniProt/SwissProtP19440   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP19440  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP19440
Splice isoforms : SwissVarP19440
PhosPhoSitePlusP19440
Domaine pattern : Prosite (Expaxy)G_GLU_TRANSPEPTIDASE (PS00462)   
Domains : Interpro (EBI)GGT_peptidase    Ntn_hydrolases_N   
Domain families : Pfam (Sanger)G_glu_transpept (PF01019)   
Domain families : Pfam (NCBI)pfam01019   
Conserved Domain (NCBI)GGT1
DMDM Disease mutations2678
Blocks (Seattle)GGT1
PDB (SRS)4GDX    4GG2    4Z9O    4ZBK    4ZC6    4ZCG   
PDB (PDBSum)4GDX    4GG2    4Z9O    4ZBK    4ZC6    4ZCG   
PDB (IMB)4GDX    4GG2    4Z9O    4ZBK    4ZC6    4ZCG   
PDB (RSDB)4GDX    4GG2    4Z9O    4ZBK    4ZC6    4ZCG   
Structural Biology KnowledgeBase4GDX    4GG2    4Z9O    4ZBK    4ZC6    4ZCG   
SCOP (Structural Classification of Proteins)4GDX    4GG2    4Z9O    4ZBK    4ZC6    4ZCG   
CATH (Classification of proteins structures)4GDX    4GG2    4Z9O    4ZBK    4ZC6    4ZCG   
SuperfamilyP19440
Human Protein AtlasENSG00000100031
Peptide AtlasP19440
HPRD01980
IPIIPI00018901   IPI00217717   IPI00339263   IPI00816658   IPI00879909   IPI00878847   IPI00878679   IPI00878471   IPI00878307   IPI00879474   IPI00879296   IPI00879120   IPI00878032   IPI00880077   IPI00879902   IPI00879740   IPI00879725   IPI00878222   IPI00877874   
Protein Interaction databases
DIP (DOE-UCLA)P19440
IntAct (EBI)P19440
FunCoupENSG00000100031
BioGRIDGGT1
STRING (EMBL)GGT1
ZODIACGGT1
Ontologies - Pathways
QuickGOP19440
Ontology : AmiGOregulation of immune system process  gamma-glutamyltransferase activity  gamma-glutamyltransferase activity  gamma-glutamyltransferase activity  protein binding  extracellular space  plasma membrane  plasma membrane  cellular amino acid metabolic process  glutamate metabolic process  leukotriene metabolic process  glutathione metabolic process  glutathione biosynthetic process  glutathione biosynthetic process  glutathione catabolic process  xenobiotic metabolic process  spermatogenesis  integral component of membrane  cysteine biosynthetic process  leukotriene biosynthetic process  anchored component of external side of plasma membrane  zymogen activation  glutathione hydrolase activity  glutathione hydrolase activity  regulation of inflammatory response  extracellular exosome  
Ontology : EGO-EBIregulation of immune system process  gamma-glutamyltransferase activity  gamma-glutamyltransferase activity  gamma-glutamyltransferase activity  protein binding  extracellular space  plasma membrane  plasma membrane  cellular amino acid metabolic process  glutamate metabolic process  leukotriene metabolic process  glutathione metabolic process  glutathione biosynthetic process  glutathione biosynthetic process  glutathione catabolic process  xenobiotic metabolic process  spermatogenesis  integral component of membrane  cysteine biosynthetic process  leukotriene biosynthetic process  anchored component of external side of plasma membrane  zymogen activation  glutathione hydrolase activity  glutathione hydrolase activity  regulation of inflammatory response  extracellular exosome  
Pathways : KEGGTaurine and hypotaurine metabolism    Cyanoamino acid metabolism    Glutathione metabolism    Arachidonic acid metabolism   
NDEx NetworkGGT1
Atlas of Cancer Signalling NetworkGGT1
Wikipedia pathwaysGGT1
Orthology - Evolution
OrthoDB2678
GeneTree (enSembl)ENSG00000100031
Phylogenetic Trees/Animal Genes : TreeFamGGT1
HOVERGENP19440
HOGENOMP19440
Homologs : HomoloGeneGGT1
Homology/Alignments : Family Browser (UCSC)GGT1
Gene fusions - Rearrangements
Fusion : MitelmanIGSF3/GGT1 [1p13.1/22q11.23]  [t(1;22)(p13;q11)]  
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGGT1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GGT1
dbVarGGT1
ClinVarGGT1
1000_GenomesGGT1 
Exome Variant ServerGGT1
ExAC (Exome Aggregation Consortium)GGT1 (select the gene name)
Genetic variants : HAPMAP2678
Genomic Variants (DGV)GGT1 [DGVbeta]
DECIPHERGGT1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGGT1 
Mutations
ICGC Data PortalGGT1 
TCGA Data PortalGGT1 
Broad Tumor PortalGGT1
OASIS PortalGGT1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGGT1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGGT1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GGT1
DgiDB (Drug Gene Interaction Database)GGT1
DoCM (Curated mutations)GGT1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GGT1 (select a term)
intoGenGGT1
Cancer3DGGT1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612346   
Orphanet10328   
MedgenGGT1
Genetic Testing Registry GGT1
NextProtP19440 [Medical]
TSGene2678
GENETestsGGT1
Target ValidationGGT1
Huge Navigator GGT1 [HugePedia]
snp3D : Map Gene to Disease2678
BioCentury BCIQGGT1
ClinGenGGT1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2678
Chemical/Pharm GKB GenePA28662
Clinical trialGGT1
Miscellaneous
canSAR (ICR)GGT1 (select the gene name)
Probes
Litterature
PubMed179 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGGT1
EVEXGGT1
GoPubMedGGT1
iHOPGGT1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 12:35:09 CEST 2017

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