Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

GGT2 (gamma-glutamyltransferase 2)

Identity

Alias_namesGGT
Other aliasGGT 2
HGNC (Hugo) GGT2
LocusID (NCBI) 728441
Atlas_Id 63771
Location 22q11.21  [Link to chromosome band 22q11]
Location_base_pair Starts at 21207973 and ends at 21209483 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute


External links

Nomenclature
HGNC (Hugo)GGT2   4251
Cards
Entrez_Gene (NCBI)GGT2  728441  gamma-glutamyltransferase 2
AliasesGGT; GGT
GeneCards (Weizmann)GGT2
Ensembl hg19 (Hinxton)ENSG00000133475 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000133475 [Gene_View]  chr22:21207973-21209483 [Contig_View]  GGT2 [Vega]
ICGC DataPortalENSG00000133475
TCGA cBioPortalGGT2
AceView (NCBI)GGT2
Genatlas (Paris)GGT2
WikiGenes728441
SOURCE (Princeton)GGT2
Genetics Home Reference (NIH)GGT2
Genomic and cartography
GoldenPath hg38 (UCSC)GGT2  -     chr22:21207973-21209483 -  22q11.21   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GGT2  -     22q11.21   [Description]    (hg19-Feb_2009)
EnsemblGGT2 - 22q11.21 [CytoView hg19]  GGT2 - 22q11.21 [CytoView hg38]
Mapping of homologs : NCBIGGT2 [Mapview hg19]  GGT2 [Mapview hg38]
OMIM137181   
Gene and transcription
Genbank (Entrez)M30474
RefSeq transcript (Entrez)NM_001351304
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GGT2
Cluster EST : UnigeneHs.568255 [ NCBI ]
CGAP (NCI)Hs.568255
Alternative Splicing GalleryENSG00000133475
Gene ExpressionGGT2 [ NCBI-GEO ]   GGT2 [ EBI - ARRAY_EXPRESS ]   GGT2 [ SEEK ]   GGT2 [ MEM ]
Gene Expression Viewer (FireBrowse)GGT2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)728441
GTEX Portal (Tissue expression)GGT2
Human Protein AtlasENSG00000133475-GGT2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP36268   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP36268  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP36268
Splice isoforms : SwissVarP36268
PhosPhoSitePlusP36268
Domaine pattern : Prosite (Expaxy)G_GLU_TRANSPEPTIDASE (PS00462)   
Domains : Interpro (EBI)GGT_peptidase    Ntn_hydrolases_N   
Domain families : Pfam (Sanger)G_glu_transpept (PF01019)   
Domain families : Pfam (NCBI)pfam01019   
Conserved Domain (NCBI)GGT2
DMDM Disease mutations728441
Blocks (Seattle)GGT2
SuperfamilyP36268
Human Protein Atlas [tissue]ENSG00000133475-GGT2 [tissue]
Peptide AtlasP36268
IPIIPI00894564   IPI00878291   IPI00880165   IPI00879415   
Protein Interaction databases
DIP (DOE-UCLA)P36268
IntAct (EBI)P36268
FunCoupENSG00000133475
BioGRIDGGT2
STRING (EMBL)GGT2
ZODIACGGT2
Ontologies - Pathways
QuickGOP36268
Ontology : AmiGOgamma-glutamyltransferase activity  gamma-glutamyltransferase activity  endoplasmic reticulum  glutathione metabolic process  glutathione catabolic process  leukotriene biosynthetic process  anchored component of external side of plasma membrane  zymogen activation  glutathione hydrolase activity  perinuclear region of cytoplasm  extracellular exosome  
Ontology : EGO-EBIgamma-glutamyltransferase activity  gamma-glutamyltransferase activity  endoplasmic reticulum  glutathione metabolic process  glutathione catabolic process  leukotriene biosynthetic process  anchored component of external side of plasma membrane  zymogen activation  glutathione hydrolase activity  perinuclear region of cytoplasm  extracellular exosome  
NDEx NetworkGGT2
Atlas of Cancer Signalling NetworkGGT2
Wikipedia pathwaysGGT2
Orthology - Evolution
OrthoDB728441
GeneTree (enSembl)ENSG00000133475
Phylogenetic Trees/Animal Genes : TreeFamGGT2
HOVERGENP36268
HOGENOMP36268
Homologs : HomoloGeneGGT2
Homology/Alignments : Family Browser (UCSC)GGT2
Gene fusions - Rearrangements
Tumor Fusion PortalGGT2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGGT2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GGT2
dbVarGGT2
ClinVarGGT2
1000_GenomesGGT2 
Exome Variant ServerGGT2
ExAC (Exome Aggregation Consortium)ENSG00000133475
GNOMAD BrowserENSG00000133475
Genetic variants : HAPMAP728441
Genomic Variants (DGV)GGT2 [DGVbeta]
DECIPHERGGT2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGGT2 
Mutations
ICGC Data PortalGGT2 
TCGA Data PortalGGT2 
Broad Tumor PortalGGT2
OASIS PortalGGT2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGGT2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGGT2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GGT2
DgiDB (Drug Gene Interaction Database)GGT2
DoCM (Curated mutations)GGT2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GGT2 (select a term)
intoGenGGT2
Cancer3DGGT2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM137181   
Orphanet
DisGeNETGGT2
MedgenGGT2
Genetic Testing Registry GGT2
NextProtP36268 [Medical]
TSGene728441
GENETestsGGT2
Target ValidationGGT2
Huge Navigator GGT2 [HugePedia]
snp3D : Map Gene to Disease728441
BioCentury BCIQGGT2
ClinGenGGT2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD728441
Chemical/Pharm GKB GenePA28663
Clinical trialGGT2
Miscellaneous
canSAR (ICR)GGT2 (select the gene name)
Probes
Litterature
PubMed25 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGGT2
EVEXGGT2
GoPubMedGGT2
iHOPGGT2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 13:43:40 CET 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.