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GGT5 (gamma-glutamyltransferase 5)

Identity

Alias_namesGGTLA1
gamma-glutamyltransferase-like activity 1
Alias_symbol (synonym)GGT-REL
Other aliasGGL
GGT 5
HGNC (Hugo) GGT5
LocusID (NCBI) 2687
Atlas_Id 54330
Location 22q11.23  [Link to chromosome band 22q11]
Location_base_pair Starts at 24615622 and ends at 24641110 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
GGT5 (22q11.23) / USP18 (22q11.21)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GGT5   4260
Cards
Entrez_Gene (NCBI)GGT5  2687  gamma-glutamyltransferase 5
AliasesGGL; GGT; GGT-REL; GGTLA1
GeneCards (Weizmann)GGT5
Ensembl hg19 (Hinxton)ENSG00000099998 [Gene_View]  chr22:24615622-24641110 [Contig_View]  GGT5 [Vega]
Ensembl hg38 (Hinxton)ENSG00000099998 [Gene_View]  chr22:24615622-24641110 [Contig_View]  GGT5 [Vega]
ICGC DataPortalENSG00000099998
TCGA cBioPortalGGT5
AceView (NCBI)GGT5
Genatlas (Paris)GGT5
WikiGenes2687
SOURCE (Princeton)GGT5
Genetics Home Reference (NIH)GGT5
Genomic and cartography
GoldenPath hg19 (UCSC)GGT5  -     chr22:24615622-24641110 -  22q11.23   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)GGT5  -     22q11.23   [Description]    (hg38-Dec_2013)
EnsemblGGT5 - 22q11.23 [CytoView hg19]  GGT5 - 22q11.23 [CytoView hg38]
Mapping of homologs : NCBIGGT5 [Mapview hg19]  GGT5 [Mapview hg38]
OMIM137168   
Gene and transcription
Genbank (Entrez)AI581436 AK225661 AK226019 AK292006 AK293683
RefSeq transcript (Entrez)NM_001099781 NM_001099782 NM_001302464 NM_001302465 NM_004121
RefSeq genomic (Entrez)NC_000022 NC_018933 NT_011520 NW_004929430
Consensus coding sequences : CCDS (NCBI)GGT5
Cluster EST : UnigeneHs.437156 [ NCBI ]
CGAP (NCI)Hs.437156
Alternative Splicing GalleryENSG00000099998
Gene ExpressionGGT5 [ NCBI-GEO ]   GGT5 [ EBI - ARRAY_EXPRESS ]   GGT5 [ SEEK ]   GGT5 [ MEM ]
Gene Expression Viewer (FireBrowse)GGT5 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2687
GTEX Portal (Tissue expression)GGT5
Protein : pattern, domain, 3D structure
UniProt/SwissProtP36269   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP36269  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP36269
Splice isoforms : SwissVarP36269
Catalytic activity : Enzyme2.3.2.2 [ Enzyme-Expasy ]   2.3.2.22.3.2.2 [ IntEnz-EBI ]   2.3.2.2 [ BRENDA ]   2.3.2.2 [ KEGG ]   
PhosPhoSitePlusP36269
Domaine pattern : Prosite (Expaxy)G_GLU_TRANSPEPTIDASE (PS00462)   
Domains : Interpro (EBI)GGT_peptidase    Ntn_hydrolases_N   
Domain families : Pfam (Sanger)G_glu_transpept (PF01019)   
Domain families : Pfam (NCBI)pfam01019   
Conserved Domain (NCBI)GGT5
DMDM Disease mutations2687
Blocks (Seattle)GGT5
SuperfamilyP36269
Human Protein AtlasENSG00000099998
Peptide AtlasP36269
HPRD00666
IPIIPI00002243   IPI00339373   IPI00877887   IPI01012039   IPI00910026   IPI00855794   IPI00877979   
Protein Interaction databases
DIP (DOE-UCLA)P36269
IntAct (EBI)P36269
FunCoupENSG00000099998
BioGRIDGGT5
STRING (EMBL)GGT5
ZODIACGGT5
Ontologies - Pathways
QuickGOP36269
Ontology : AmiGOgamma-glutamyltransferase activity  plasma membrane  proteolysis  cellular amino acid metabolic process  leukotriene metabolic process  glutathione metabolic process  glutathione biosynthetic process  inflammatory response  integral component of membrane  leukotriene biosynthetic process  anchored component of external side of plasma membrane  glutathione hydrolase activity  
Ontology : EGO-EBIgamma-glutamyltransferase activity  plasma membrane  proteolysis  cellular amino acid metabolic process  leukotriene metabolic process  glutathione metabolic process  glutathione biosynthetic process  inflammatory response  integral component of membrane  leukotriene biosynthetic process  anchored component of external side of plasma membrane  glutathione hydrolase activity  
Pathways : KEGGTaurine and hypotaurine metabolism    Cyanoamino acid metabolism    Glutathione metabolism    Arachidonic acid metabolism   
NDEx NetworkGGT5
Atlas of Cancer Signalling NetworkGGT5
Wikipedia pathwaysGGT5
Orthology - Evolution
OrthoDB2687
GeneTree (enSembl)ENSG00000099998
Phylogenetic Trees/Animal Genes : TreeFamGGT5
HOVERGENP36269
HOGENOMP36269
Homologs : HomoloGeneGGT5
Homology/Alignments : Family Browser (UCSC)GGT5
Gene fusions - Rearrangements
Fusion : MitelmanGGT5/USP18 [22q11.23/22q11.21]  
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGGT5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GGT5
dbVarGGT5
ClinVarGGT5
1000_GenomesGGT5 
Exome Variant ServerGGT5
ExAC (Exome Aggregation Consortium)GGT5 (select the gene name)
Genetic variants : HAPMAP2687
Genomic Variants (DGV)GGT5 [DGVbeta]
DECIPHER (Syndromes)22:24615622-24641110  ENSG00000099998
CONAN: Copy Number AnalysisGGT5 
Mutations
ICGC Data PortalGGT5 
TCGA Data PortalGGT5 
Broad Tumor PortalGGT5
OASIS PortalGGT5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGGT5  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGGT5
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GGT5
DgiDB (Drug Gene Interaction Database)GGT5
DoCM (Curated mutations)GGT5 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GGT5 (select a term)
intoGenGGT5
Cancer3DGGT5(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM137168   
Orphanet
MedgenGGT5
Genetic Testing Registry GGT5
NextProtP36269 [Medical]
TSGene2687
GENETestsGGT5
Huge Navigator GGT5 [HugePedia]
snp3D : Map Gene to Disease2687
BioCentury BCIQGGT5
ClinGenGGT5
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2687
Chemical/Pharm GKB GenePA162389442
Clinical trialGGT5
Miscellaneous
canSAR (ICR)GGT5 (select the gene name)
Probes
Litterature
PubMed18 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGGT5
EVEXGGT5
GoPubMedGGT5
iHOPGGT5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Thu Mar 30 15:02:20 CEST 2017

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