GGT7 (gamma-glutamyltransferase 7)

2007-02-01  

Identity

HGNC
LOCATION
20q11.22
LOCUSID
ALIAS
D20S101,GGT4,GGTL3,GGTL5
FUSION GENES

Other Information

Locus ID:

NCBI: 2686
MIM: 612342
HGNC: 4259
Ensembl: ENSG00000131067

Variants:

dbSNP: 2686
ClinVar: 2686
TCGA: ENSG00000131067
COSMIC: GGT7

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000131067ENST00000336431Q9UJ14
ENSG00000131067ENST00000427420A2A2G5
ENSG00000131067ENST00000469018A0A0D9SFH0
ENSG00000131067ENST00000470952A0A0D9SF08

Expression (GTEx)

0
50
100
150
200

Pathways

PathwaySourceExternal ID
Taurine and hypotaurine metabolismKEGGko00430
Glutathione metabolismKEGGko00480
Taurine and hypotaurine metabolismKEGGhsa00430
Glutathione metabolismKEGGhsa00480
Metabolic pathwaysKEGGhsa01100
MetabolismREACTOMER-HSA-1430728
Biological oxidationsREACTOMER-HSA-211859
Phase II conjugationREACTOMER-HSA-156580
Glutathione conjugationREACTOMER-HSA-156590
Glutathione synthesis and recyclingREACTOMER-HSA-174403
Aflatoxin activation and detoxificationREACTOMER-HSA-5423646

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
122701272002Molecular cloning and characterization of CT120, a novel membrane-associated gene involved in amino acid transport and glutathione metabolism.4
258846242015γ-Glutamyl transferase 7 is a novel regulator of glioblastoma growth.4

Citation

Dessen P

GGT7 (gamma-glutamyltransferase 7)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/43718/ggt7