Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

GH2 (growth hormone 2)

Identity

Alias_symbol (synonym)GH-V
GHV
GHL
hGH-V
Other aliasGHB2
HGNC (Hugo) GH2
LocusID (NCBI) 2689
Atlas_Id 45698
Location 17q23.3  [Link to chromosome band 17q23]
Location_base_pair Starts at 63880212 and ends at 63881942 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
BCAS3 (17q23.2) / GH2 (17q23.3)RUSC2 (9p13.3) / GH2 (17q23.3)BCAS3 17q23.2 / GH2 17q23.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GH2   4262
Cards
Entrez_Gene (NCBI)GH2  2689  growth hormone 2
AliasesGH-V; GHB2; GHL; GHV; 
hGH-V
GeneCards (Weizmann)GH2
Ensembl hg19 (Hinxton)ENSG00000136487 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000136487 [Gene_View]  chr17:63880212-63881942 [Contig_View]  GH2 [Vega]
ICGC DataPortalENSG00000136487
TCGA cBioPortalGH2
AceView (NCBI)GH2
Genatlas (Paris)GH2
WikiGenes2689
SOURCE (Princeton)GH2
Genetics Home Reference (NIH)GH2
Genomic and cartography
GoldenPath hg38 (UCSC)GH2  -     chr17:63880212-63881942 -  17q23.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GH2  -     17q23.3   [Description]    (hg19-Feb_2009)
EnsemblGH2 - 17q23.3 [CytoView hg19]  GH2 - 17q23.3 [CytoView hg38]
Mapping of homologs : NCBIGH2 [Mapview hg19]  GH2 [Mapview hg38]
OMIM139240   
Gene and transcription
Genbank (Entrez)AB451332 AB451477 AF006060 AF006061 AK312194
RefSeq transcript (Entrez)NM_002059 NM_022556 NM_022557 NM_022558
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GH2
Cluster EST : UnigeneHs.654390 [ NCBI ]
CGAP (NCI)Hs.654390
Alternative Splicing GalleryENSG00000136487
Gene ExpressionGH2 [ NCBI-GEO ]   GH2 [ EBI - ARRAY_EXPRESS ]   GH2 [ SEEK ]   GH2 [ MEM ]
Gene Expression Viewer (FireBrowse)GH2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2689
GTEX Portal (Tissue expression)GH2
Protein : pattern, domain, 3D structure
UniProt/SwissProtP01242   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP01242  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP01242
Splice isoforms : SwissVarP01242
PhosPhoSitePlusP01242
Domaine pattern : Prosite (Expaxy)SOMATOTROPIN_1 (PS00266)    SOMATOTROPIN_2 (PS00338)   
Domains : Interpro (EBI)4_helix_cytokine-like_core    4_helix_cytokine_core    Somatotropin    Somatotropin_CS   
Domain families : Pfam (Sanger)Hormone_1 (PF00103)   
Domain families : Pfam (NCBI)pfam00103   
Conserved Domain (NCBI)GH2
DMDM Disease mutations2689
Blocks (Seattle)GH2
SuperfamilyP01242
Human Protein AtlasENSG00000136487
Peptide AtlasP01242
HPRD00750
IPIIPI00000890   IPI00218361   IPI00021672   IPI00021673   
Protein Interaction databases
DIP (DOE-UCLA)P01242
IntAct (EBI)P01242
FunCoupENSG00000136487
BioGRIDGH2
STRING (EMBL)GH2
ZODIACGH2
Ontologies - Pathways
QuickGOP01242
Ontology : AmiGOhormone activity  extracellular region  endosome lumen  JAK-STAT cascade involved in growth hormone signaling pathway  
Ontology : EGO-EBIhormone activity  extracellular region  endosome lumen  JAK-STAT cascade involved in growth hormone signaling pathway  
Pathways : KEGGCytokine-cytokine receptor interaction    Neuroactive ligand-receptor interaction    PI3K-Akt signaling pathway    Jak-STAT signaling pathway   
NDEx NetworkGH2
Atlas of Cancer Signalling NetworkGH2
Wikipedia pathwaysGH2
Orthology - Evolution
OrthoDB2689
GeneTree (enSembl)ENSG00000136487
Phylogenetic Trees/Animal Genes : TreeFamGH2
HOVERGENP01242
HOGENOMP01242
Homologs : HomoloGeneGH2
Homology/Alignments : Family Browser (UCSC)GH2
Gene fusions - Rearrangements
Fusion : MitelmanBCAS3/GH2 [17q23.2/17q23.3]  [t(17;17)(q23;q23)]  
Fusion: TCGABCAS3 17q23.2 GH2 17q23.3 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGH2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GH2
dbVarGH2
ClinVarGH2
1000_GenomesGH2 
Exome Variant ServerGH2
ExAC (Exome Aggregation Consortium)GH2 (select the gene name)
Genetic variants : HAPMAP2689
Genomic Variants (DGV)GH2 [DGVbeta]
DECIPHERGH2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGH2 
Mutations
ICGC Data PortalGH2 
TCGA Data PortalGH2 
Broad Tumor PortalGH2
OASIS PortalGH2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGH2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGH2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GH2
DgiDB (Drug Gene Interaction Database)GH2
DoCM (Curated mutations)GH2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GH2 (select a term)
intoGenGH2
Cancer3DGH2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM139240   
Orphanet
MedgenGH2
Genetic Testing Registry GH2
NextProtP01242 [Medical]
TSGene2689
GENETestsGH2
Huge Navigator GH2 [HugePedia]
snp3D : Map Gene to Disease2689
BioCentury BCIQGH2
ClinGenGH2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2689
Chemical/Pharm GKB GenePA28672
Clinical trialGH2
Miscellaneous
canSAR (ICR)GH2 (select the gene name)
Probes
Litterature
PubMed42 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGH2
EVEXGH2
GoPubMedGH2
iHOPGH2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri May 19 12:17:11 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.