GHRH (growth hormone releasing hormone)

2003-10-01  

Identity

HGNC
LOCATION
20q11.23
LOCUSID
ALIAS
GHRF,GRF,INN
FUSION GENES

Other Information

Locus ID:

NCBI: 2691
MIM: 139190
HGNC: 4265
Ensembl: ENSG00000118702

Variants:

dbSNP: 2691
ClinVar: 2691
TCGA: ENSG00000118702
COSMIC: GHRH

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000118702ENST00000237527P01286
ENSG00000118702ENST00000373611P01286
ENSG00000118702ENST00000373614P01286

Expression (GTEx)

0
1
2
3
4
5
6

Pathways

PathwaySourceExternal ID
Signal TransductionREACTOMER-HSA-162582
Signaling by GPCRREACTOMER-HSA-372790
GPCR ligand bindingREACTOMER-HSA-500792
Class B/2 (Secretin family receptors)REACTOMER-HSA-373080
Glucagon-type ligand receptorsREACTOMER-HSA-420092
GPCR downstream signalingREACTOMER-HSA-388396
G alpha (s) signalling eventsREACTOMER-HSA-418555

References

Pubmed IDYearTitleCitations
207340642010A large-scale candidate gene association study of age at menarche and age at natural menopause.38
190860532009Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment.34
208106042010Eighteen insulin-like growth factor pathway genes, circulating levels of IGF-I and its binding protein, and risk of prostate and breast cancer.34
206341972010Comprehensive analysis of common genetic variation in 61 genes related to steroid hormone and insulin-like growth factor-I metabolism and breast cancer risk in the NCI breast and prostate cancer cohort consortium.25
204530002010A Large-scale genetic association study of esophageal adenocarcinoma risk.23
194532612009High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men.20
121869802002The expression of growth hormone-releasing hormone (GHRH) and splice variants of its receptor in human gastroenteropancreatic carcinomas.19
123644622002Expression of growth hormone-releasing hormone and its receptor splice variants in human prostate cancer.19
214782112011Cardiovascular actions of the ghrelin gene-derived peptides and growth hormone-releasing hormone.19
303441242018P53, GHRH, inflammation and cancer.16

Citation

Dessen P

GHRH (growth hormone releasing hormone)

Atlas Genet Cytogenet Oncol Haematol. 2003-10-01

Online version: http://atlasgeneticsoncology.org/gene/40712/ghrh