Atlas of Genetics and Cytogenetics in Oncology and Haematology

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GHSR (growth hormone secretagogue receptor)

Identity

Other names-
HGNC (Hugo) GHSR
LocusID (NCBI) 2693
Location 3q26.31
Location_base_pair Starts at 172165333 and ends at 172166246 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)GHSR   4267
Entrez_Gene (NCBI)GHSR  2693  growth hormone secretagogue receptor
Cards
GeneCards (Weizmann)GHSR
Ensembl (Hinxton)ENSG00000121853 [Gene_View]  chr3:172165333-172166246 [Contig_View]  GHSR [Vega]
AceView (NCBI)GHSR
Genatlas (Paris)GHSR
SOURCE (Stanford)NM_004122 NM_198407
Genomic and cartography
GoldenPath (UCSC)GHSR  -  3q26.31   chr3:172165333-172166246 -  3q26.31   [Description]    (hg19-Feb_2009)
EnsemblGHSR - 3q26.31 [CytoView]
Mapping of homologs : NCBIGHSR [Mapview]
OMIM601898   604271   
Gene and transcription
Genbank (Entrez)AY429112 BC069068 BC069374 BC113547 HQ258211
RefSeq transcript (SRS)NM_004122 NM_198407
RefSeq transcript (Entrez)NM_004122 NM_198407
RefSeq genomic (SRS)AC_000135 NC_000003 NC_018914 NG_021159 NT_005612 NW_001838884 NW_004078013
RefSeq genomic (Entrez)AC_000135 NC_000003 NC_018914 NG_021159 NT_005612 NW_001838884 NW_004078013
Consensus coding sequences : CCDS (NCBI)GHSR
Cluster EST : UnigeneHs.130212 [ SRS ] Hs.130212 [ NCBI ]
CGAP (NCI)Hs.130212
Alternative Splicing : Fast-db (Paris)GSHG0022238
Alternative Splicing GalleryENSG00000121853
Gene ExpressionGHSR [ NCBI-GEO ]   GHSR [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ92847 (SRS) Q92847 (Uniprot)
NextProtQ92847
With graphics : InterProQ92847
Splice isoforms : SwissVarQ92847(Swissvar)
Domaine pattern : Prosite (SRS)G_PROTEIN_RECEP_F1_1 (PS00237)    G_PROTEIN_RECEP_F1_2 (PS50262)   
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F1_1 (PS00237)    G_PROTEIN_RECEP_F1_2 (PS50262)   
Domains : Interpro (SRS)7TM_GPCR_Rhodpsn    GHS1_rcpt    GPCR_Rhodpsn_supfam   
Domains : Interpro (EBI)7TM_GPCR_Rhodpsn    GHS1_rcpt    GPCR_Rhodpsn_supfam   
Related proteins : CluSTrQ92847
Domain families : Pfam (SRS)7tm_1 (PF00001)   
Domain families : Pfam (Sanger)7tm_1 (PF00001)   
Domain families : Pfam (NCBI)pfam00001   
DMDM2693
Blocks (Seattle)Q92847
Human Protein AtlasENSG00000121853
HPRD03541
IPIIPI00023793   IPI00219687   
Protein Interaction databases
DIP (DOE-UCLA)Q92847
IntAct (EBI)Q92847
FunCoupENSG00000121853
REACTOMEGHSR
Protein Interaction Database2693
BioGRIDGHSR
InParanoidQ92847
Interologous Interaction database Q92847
IntegromeDBGHSR
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)GHSR
SNP (GeneSNP Utah)GHSR
SNP : HGBaseGHSR
Genetic variants : HAPMAPGHSR
Somatic Mutations in Cancer : COSMICGHSR 
CONAN: Copy Number AnalysisGHSR 
Mutations and Diseases : HGMDGHSR
OMIM601898    604271   
GENETests601898    604271   
Disease Genetic AssociationGHSR
Huge Navigator GHSR [HugePedia]  GHSR [HugeCancerGEM]
Genomic VariantsGHSR  GHSR [DGVbeta]
snp3D : Map Gene to Disease2693
General knowledge
Homologs : HomoloGeneGHSR
Homology/Alignments : Family Browser (UCSC)GHSR
Phylogenetic Trees/Animal Genes : TreeFamGHSR
Chemical/Protein Interactions : CTD2693
Chemical/Pharm GKB GenePA28677
Clinical trialGHSR
Cancer Resource (Charite)ENSG00000121853
Ontology : AmiGOgrowth hormone secretagogue receptor activity  G-protein coupled receptor activity  plasma membrane  G-protein coupled receptor signaling pathway  actin polymerization or depolymerization  adult feeding behavior  response to hormone stimulus  hormone-mediated signaling pathway  cell surface  integral to membrane  growth hormone-releasing hormone receptor activity  peptide hormone binding  growth hormone secretion  response to food  positive regulation of appetite  negative regulation of interleukin-1 beta production  cellular response to insulin stimulus  positive regulation of multicellular organism growth  negative regulation of tumor necrosis factor biosynthetic process  neuron projection  regulation of hindgut contraction  positive regulation of insulin-like growth factor receptor signaling pathway  membrane raft  negative regulation of interleukin-6 biosynthetic process  positive regulation of fatty acid metabolic process  negative regulation of insulin secretion  decidualization  negative regulation of inflammatory response  regulation of synapse assembly  
Ontology : EGO-EBIgrowth hormone secretagogue receptor activity  G-protein coupled receptor activity  plasma membrane  G-protein coupled receptor signaling pathway  actin polymerization or depolymerization  adult feeding behavior  response to hormone stimulus  hormone-mediated signaling pathway  cell surface  integral to membrane  growth hormone-releasing hormone receptor activity  peptide hormone binding  growth hormone secretion  response to food  positive regulation of appetite  negative regulation of interleukin-1 beta production  cellular response to insulin stimulus  positive regulation of multicellular organism growth  negative regulation of tumor necrosis factor biosynthetic process  neuron projection  regulation of hindgut contraction  positive regulation of insulin-like growth factor receptor signaling pathway  membrane raft  negative regulation of interleukin-6 biosynthetic process  positive regulation of fatty acid metabolic process  negative regulation of insulin secretion  decidualization  negative regulation of inflammatory response  regulation of synapse assembly  
Pathways : KEGGNeuroactive ligand-receptor interaction
Other databases
Probes
Litterature
PubMed104 Pubmed reference(s) in Entrez
PubGeneGHSR
iHOPGHSR
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 1 12:42:54 CEST 2013
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