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GIF (gastric intrinsic factor)

Identity

Alias_namesgastric intrinsic factor (vitamin B synthesis)
Alias_symbol (synonym)TCN3
IF
IFMH
INF
Other alias
HGNC (Hugo) GIF
LocusID (NCBI) 2694
Atlas_Id 52926
Location 11q12.1  [Link to chromosome band 11q12]
Location_base_pair Starts at 59829273 and ends at 59845501 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
PIGR (1q32.1) / GIF (11q12.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GIF   4268
Cards
Entrez_Gene (NCBI)GIF  2694  gastric intrinsic factor
AliasesIF; IFMH; INF; TCN3
GeneCards (Weizmann)GIF
Ensembl hg19 (Hinxton)ENSG00000134812 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000134812 [Gene_View]  chr11:59829273-59845501 [Contig_View]  GIF [Vega]
ICGC DataPortalENSG00000134812
TCGA cBioPortalGIF
AceView (NCBI)GIF
Genatlas (Paris)GIF
WikiGenes2694
SOURCE (Princeton)GIF
Genetics Home Reference (NIH)GIF
Genomic and cartography
GoldenPath hg38 (UCSC)GIF  -     chr11:59829273-59845501 -  11q12.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GIF  -     11q12.1   [Description]    (hg19-Feb_2009)
EnsemblGIF - 11q12.1 [CytoView hg19]  GIF - 11q12.1 [CytoView hg38]
Mapping of homologs : NCBIGIF [Mapview hg19]  GIF [Mapview hg38]
OMIM261000   609342   
Gene and transcription
Genbank (Entrez)AK301290 AK301295 AK314275 BC037958 DQ892469
RefSeq transcript (Entrez)NM_005142
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GIF
Cluster EST : UnigeneHs.110014 [ NCBI ]
CGAP (NCI)Hs.110014
Alternative Splicing GalleryENSG00000134812
Gene ExpressionGIF [ NCBI-GEO ]   GIF [ EBI - ARRAY_EXPRESS ]   GIF [ SEEK ]   GIF [ MEM ]
Gene Expression Viewer (FireBrowse)GIF [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2694
GTEX Portal (Tissue expression)GIF
Protein : pattern, domain, 3D structure
UniProt/SwissProtP27352   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP27352  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP27352
Splice isoforms : SwissVarP27352
PhosPhoSitePlusP27352
Domaine pattern : Prosite (Expaxy)COBALAMIN_BINDING (PS00468)   
Domains : Interpro (EBI)Cbl-bd_transpt_euk    DUF4430   
Domain families : Pfam (Sanger)Cobalamin_bind (PF01122)    DUF4430 (PF14478)   
Domain families : Pfam (NCBI)pfam01122    pfam14478   
Conserved Domain (NCBI)GIF
DMDM Disease mutations2694
Blocks (Seattle)GIF
PDB (SRS)2CKT    2PMV    3KQ4   
PDB (PDBSum)2CKT    2PMV    3KQ4   
PDB (IMB)2CKT    2PMV    3KQ4   
PDB (RSDB)2CKT    2PMV    3KQ4   
Structural Biology KnowledgeBase2CKT    2PMV    3KQ4   
SCOP (Structural Classification of Proteins)2CKT    2PMV    3KQ4   
CATH (Classification of proteins structures)2CKT    2PMV    3KQ4   
SuperfamilyP27352
Human Protein AtlasENSG00000134812
Peptide AtlasP27352
HPRD02024
IPIIPI00018169   IPI01011862   IPI00983052   
Protein Interaction databases
DIP (DOE-UCLA)P27352
IntAct (EBI)P27352
FunCoupENSG00000134812
BioGRIDGIF
STRING (EMBL)GIF
ZODIACGIF
Ontologies - Pathways
QuickGOP27352
Ontology : AmiGOextracellular region  extracellular space  endosome  endosome  microvillus  cobalt ion transport  cobalamin metabolic process  cobalamin transport  apical plasma membrane  cobalamin binding  lysosomal lumen  
Ontology : EGO-EBIextracellular region  extracellular space  endosome  endosome  microvillus  cobalt ion transport  cobalamin metabolic process  cobalamin transport  apical plasma membrane  cobalamin binding  lysosomal lumen  
Pathways : KEGGVitamin digestion and absorption   
NDEx NetworkGIF
Atlas of Cancer Signalling NetworkGIF
Wikipedia pathwaysGIF
Orthology - Evolution
OrthoDB2694
GeneTree (enSembl)ENSG00000134812
Phylogenetic Trees/Animal Genes : TreeFamGIF
HOVERGENP27352
HOGENOMP27352
Homologs : HomoloGeneGIF
Homology/Alignments : Family Browser (UCSC)GIF
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGIF [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GIF
dbVarGIF
ClinVarGIF
1000_GenomesGIF 
Exome Variant ServerGIF
ExAC (Exome Aggregation Consortium)GIF (select the gene name)
Genetic variants : HAPMAP2694
Genomic Variants (DGV)GIF [DGVbeta]
DECIPHERGIF [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGIF 
Mutations
ICGC Data PortalGIF 
TCGA Data PortalGIF 
Broad Tumor PortalGIF
OASIS PortalGIF [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGIF  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGIF
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GIF
DgiDB (Drug Gene Interaction Database)GIF
DoCM (Curated mutations)GIF (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GIF (select a term)
intoGenGIF
Cancer3DGIF(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM261000    609342   
Orphanet3359   
MedgenGIF
Genetic Testing Registry GIF
NextProtP27352 [Medical]
TSGene2694
GENETestsGIF
Huge Navigator GIF [HugePedia]
snp3D : Map Gene to Disease2694
BioCentury BCIQGIF
ClinGenGIF
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2694
Chemical/Pharm GKB GenePA28678
Clinical trialGIF
Miscellaneous
canSAR (ICR)GIF (select the gene name)
Probes
Litterature
PubMed23 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGIF
EVEXGIF
GoPubMedGIF
iHOPGIF
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri May 19 12:17:13 CEST 2017

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