Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

GJA3 (gap junction protein alpha 3)

Identity

Alias_namesCZP3
gap junction protein, alpha 3, 46kD (connexin 46)
gap junction protein, alpha 3, 46kDa (connexin 46)
gap junction protein, alpha 3, 46kDa
Alias_symbol (synonym)CX46
Other aliasCTRCT14
HGNC (Hugo) GJA3
LocusID (NCBI) 2700
Atlas_Id 51586
Location 13q12.11  [Link to chromosome band 13q12]
Location_base_pair Starts at 20712395 and ends at 20735183 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GJA3   4277
Cards
Entrez_Gene (NCBI)GJA3  2700  gap junction protein alpha 3
AliasesCTRCT14; CX46; CZP3
GeneCards (Weizmann)GJA3
Ensembl hg19 (Hinxton)ENSG00000121743 [Gene_View]  chr13:20712395-20735183 [Contig_View]  GJA3 [Vega]
Ensembl hg38 (Hinxton)ENSG00000121743 [Gene_View]  chr13:20712395-20735183 [Contig_View]  GJA3 [Vega]
ICGC DataPortalENSG00000121743
TCGA cBioPortalGJA3
AceView (NCBI)GJA3
Genatlas (Paris)GJA3
WikiGenes2700
SOURCE (Princeton)GJA3
Genetics Home Reference (NIH)GJA3
Genomic and cartography
GoldenPath hg19 (UCSC)GJA3  -     chr13:20712395-20735183 -  13q12.11   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)GJA3  -     13q12.11   [Description]    (hg38-Dec_2013)
EnsemblGJA3 - 13q12.11 [CytoView hg19]  GJA3 - 13q12.11 [CytoView hg38]
Mapping of homologs : NCBIGJA3 [Mapview hg19]  GJA3 [Mapview hg38]
OMIM121015   601885   
Gene and transcription
Genbank (Entrez)BC121137 BF726530 DR003755
RefSeq transcript (Entrez)NM_021954
RefSeq genomic (Entrez)NC_000013 NC_018924 NG_016399 NT_024524 NW_004929388
Consensus coding sequences : CCDS (NCBI)GJA3
Cluster EST : UnigeneHs.130313 [ NCBI ]
CGAP (NCI)Hs.130313
Alternative Splicing GalleryENSG00000121743
Gene ExpressionGJA3 [ NCBI-GEO ]   GJA3 [ EBI - ARRAY_EXPRESS ]   GJA3 [ SEEK ]   GJA3 [ MEM ]
Gene Expression Viewer (FireBrowse)GJA3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2700
GTEX Portal (Tissue expression)GJA3
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y6H8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y6H8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y6H8
Splice isoforms : SwissVarQ9Y6H8
PhosPhoSitePlusQ9Y6H8
Domaine pattern : Prosite (Expaxy)CONNEXINS_1 (PS00407)    CONNEXINS_2 (PS00408)   
Domains : Interpro (EBI)Connexin    Connexin46    Connexin_CCC    Connexin_CS    Connexin_N   
Domain families : Pfam (Sanger)Connexin (PF00029)   
Domain families : Pfam (NCBI)pfam00029   
Domain families : Smart (EMBL)CNX (SM00037)  Connexin_CCC (SM01089)  
Conserved Domain (NCBI)GJA3
DMDM Disease mutations2700
Blocks (Seattle)GJA3
SuperfamilyQ9Y6H8
Human Protein AtlasENSG00000121743
Peptide AtlasQ9Y6H8
HPRD00415
IPIIPI00221385   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y6H8
IntAct (EBI)Q9Y6H8
FunCoupENSG00000121743
BioGRIDGJA3
STRING (EMBL)GJA3
ZODIACGJA3
Ontologies - Pathways
QuickGOQ9Y6H8
Ontology : AmiGOgap junction channel activity  connexon complex  transport  cell-cell signaling  visual perception  response to pH  integral component of membrane  response to hydrogen peroxide  identical protein binding  membrane raft  transmembrane transport  
Ontology : EGO-EBIgap junction channel activity  connexon complex  transport  cell-cell signaling  visual perception  response to pH  integral component of membrane  response to hydrogen peroxide  identical protein binding  membrane raft  transmembrane transport  
NDEx NetworkGJA3
Atlas of Cancer Signalling NetworkGJA3
Wikipedia pathwaysGJA3
Orthology - Evolution
OrthoDB2700
GeneTree (enSembl)ENSG00000121743
Phylogenetic Trees/Animal Genes : TreeFamGJA3
HOVERGENQ9Y6H8
HOGENOMQ9Y6H8
Homologs : HomoloGeneGJA3
Homology/Alignments : Family Browser (UCSC)GJA3
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGJA3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GJA3
dbVarGJA3
ClinVarGJA3
1000_GenomesGJA3 
Exome Variant ServerGJA3
ExAC (Exome Aggregation Consortium)GJA3 (select the gene name)
Genetic variants : HAPMAP2700
Genomic Variants (DGV)GJA3 [DGVbeta]
DECIPHER (Syndromes)13:20712395-20735183  ENSG00000121743
CONAN: Copy Number AnalysisGJA3 
Mutations
ICGC Data PortalGJA3 
TCGA Data PortalGJA3 
Broad Tumor PortalGJA3
OASIS PortalGJA3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGJA3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGJA3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)Eye diseases - LOVD
BioMutasearch GJA3
DgiDB (Drug Gene Interaction Database)GJA3
DoCM (Curated mutations)GJA3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GJA3 (select a term)
intoGenGJA3
Cancer3DGJA3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM121015    601885   
Orphanet14001    14008    14010   
MedgenGJA3
Genetic Testing Registry GJA3
NextProtQ9Y6H8 [Medical]
TSGene2700
GENETestsGJA3
Huge Navigator GJA3 [HugePedia]
snp3D : Map Gene to Disease2700
BioCentury BCIQGJA3
ClinGenGJA3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2700
Chemical/Pharm GKB GenePA28688
Clinical trialGJA3
Miscellaneous
canSAR (ICR)GJA3 (select the gene name)
Probes
Litterature
PubMed49 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGJA3
EVEXGJA3
GoPubMedGJA3
iHOPGJA3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Mar 30 15:02:25 CEST 2017

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.