Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2700
MIM: 121015
HGNC: 4277
Ensembl: ENSG00000121743
Variants:
dbSNP: 2700
ClinVar: 2700
TCGA: ENSG00000121743
COSMIC: GJA3
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000121743 | ENST00000241125 | Q9Y6H8 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38178039 | 2024 | Novel and known variants in GJA3 and LIM2 in congenital cataract families from North India. | 0 |
| 38178039 | 2024 | Novel and known variants in GJA3 and LIM2 in congenital cataract families from North India. | 0 |
| 37589989 | 2023 | GJA3 Genetic Variation and Autosomal Dominant Congenital Cataracts and Glaucoma Following Cataract Surgery. | 2 |
| 37892142 | 2023 | Connexins in Cancer, the Possible Role of Connexin46 as a Cancer Stem Cell-Determining Protein. | 0 |
| 37589989 | 2023 | GJA3 Genetic Variation and Autosomal Dominant Congenital Cataracts and Glaucoma Following Cataract Surgery. | 2 |
| 37892142 | 2023 | Connexins in Cancer, the Possible Role of Connexin46 as a Cancer Stem Cell-Determining Protein. | 0 |
| 33140904 | 2021 | Connexins in melanoma: Potential role of Cx46 in its aggressiveness. | 5 |
| 34226295 | 2021 | Aging-dependent loss of GAP junction proteins Cx46 and Cx50 in the fiber cells of human and mouse lenses accounts for the diminished coupling conductance. | 8 |
| 34830485 | 2021 | Connexin46 Expression Enhances Cancer Stem Cell and Epithelial-to-Mesenchymal Transition Characteristics of Human Breast Cancer MCF-7 Cells. | 12 |
| 33140904 | 2021 | Connexins in melanoma: Potential role of Cx46 in its aggressiveness. | 5 |
| 34226295 | 2021 | Aging-dependent loss of GAP junction proteins Cx46 and Cx50 in the fiber cells of human and mouse lenses accounts for the diminished coupling conductance. | 8 |
| 34830485 | 2021 | Connexin46 Expression Enhances Cancer Stem Cell and Epithelial-to-Mesenchymal Transition Characteristics of Human Breast Cancer MCF-7 Cells. | 12 |
| 32353936 | 2020 | Connexin-46 Contained in Extracellular Vesicles Enhance Malignancy Features in Breast Cancer Cells. | 15 |
| 32808810 | 2020 | Identification of GJA3 p.S50P Mutation in a Chinese Family with Autosomal Dominant Congenital Cataract and Its Underlying Pathogenesis. | 2 |
| 32971763 | 2020 | Lens Connexin Channels Show Differential Permeability to Signaling Molecules. | 12 |
Citation
Dessen P
GJA3 (gap junction protein alpha 3)
Atlas Genet Cytogenet Oncol Haematol. 2010-08-01
Online version: http://atlasgeneticsoncology.org/gene/51586/gja3
