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GK (glycerol kinase)

Identity

Alias_symbol (synonym)GK1
GKD
Other alias
HGNC (Hugo) GK
LocusID (NCBI) 2710
Atlas_Id 63804
Location Xp21.2  [Link to chromosome band Xp21]
Location_base_pair Starts at 30653359 and ends at 30731460 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
TPM1 (15q22.2) / GK (Xp21.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GK   4289
LRG (Locus Reference Genomic)LRG_848
Cards
Entrez_Gene (NCBI)GK  2710  glycerol kinase
AliasesGK1; GKD
GeneCards (Weizmann)GK
Ensembl hg19 (Hinxton)ENSG00000198814 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000198814 [Gene_View]  chrX:30653359-30731460 [Contig_View]  GK [Vega]
ICGC DataPortalENSG00000198814
TCGA cBioPortalGK
AceView (NCBI)GK
Genatlas (Paris)GK
WikiGenes2710
SOURCE (Princeton)GK
Genetics Home Reference (NIH)GK
Genomic and cartography
GoldenPath hg38 (UCSC)GK  -     chrX:30653359-30731460 +  Xp21.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GK  -     Xp21.2   [Description]    (hg19-Feb_2009)
EnsemblGK - Xp21.2 [CytoView hg19]  GK - Xp21.2 [CytoView hg38]
Mapping of homologs : NCBIGK [Mapview hg19]  GK [Mapview hg38]
OMIM300474   307030   
Gene and transcription
Genbank (Entrez)AA689298 AK294304 AK294938 AK308238 AK313215
RefSeq transcript (Entrez)NM_000167 NM_001128127 NM_001205019 NM_203391
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GK
Cluster EST : UnigeneHs.1466 [ NCBI ]
CGAP (NCI)Hs.1466
Alternative Splicing GalleryENSG00000198814
Gene ExpressionGK [ NCBI-GEO ]   GK [ EBI - ARRAY_EXPRESS ]   GK [ SEEK ]   GK [ MEM ]
Gene Expression Viewer (FireBrowse)GK [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2710
GTEX Portal (Tissue expression)GK
Protein : pattern, domain, 3D structure
UniProt/SwissProtP32189   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP32189  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP32189
Splice isoforms : SwissVarP32189
Catalytic activity : Enzyme2.7.1.30 [ Enzyme-Expasy ]   2.7.1.302.7.1.30 [ IntEnz-EBI ]   2.7.1.30 [ BRENDA ]   2.7.1.30 [ KEGG ]   
PhosPhoSitePlusP32189
Domaine pattern : Prosite (Expaxy)FGGY_KINASES_1 (PS00933)    FGGY_KINASES_2 (PS00445)   
Domains : Interpro (EBI)Carb_kinase_FGGY    Carb_kinase_FGGY_C    Carb_kinase_FGGY_CS    Carb_kinase_FGGY_N    Glycerol_kin   
Domain families : Pfam (Sanger)FGGY_C (PF02782)    FGGY_N (PF00370)   
Domain families : Pfam (NCBI)pfam02782    pfam00370   
Conserved Domain (NCBI)GK
DMDM Disease mutations2710
Blocks (Seattle)GK
SuperfamilyP32189
Human Protein AtlasENSG00000198814
Peptide AtlasP32189
HPRD08363
Protein Interaction databases
DIP (DOE-UCLA)P32189
IntAct (EBI)P32189
FunCoupENSG00000198814
BioGRIDGK
STRING (EMBL)GK
ZODIACGK
Ontologies - Pathways
QuickGOP32189
Ontology : AmiGOglycerol kinase activity  glycerol kinase activity  glycerol kinase activity  protein binding  ATP binding  mitochondrion  mitochondrial outer membrane  cytosol  glycerol metabolic process  triglyceride metabolic process  phosphorylation  triglyceride biosynthetic process  glycerol catabolic process  glycerol-3-phosphate biosynthetic process  extracellular exosome  
Ontology : EGO-EBIglycerol kinase activity  glycerol kinase activity  glycerol kinase activity  protein binding  ATP binding  mitochondrion  mitochondrial outer membrane  cytosol  glycerol metabolic process  triglyceride metabolic process  phosphorylation  triglyceride biosynthetic process  glycerol catabolic process  glycerol-3-phosphate biosynthetic process  extracellular exosome  
Pathways : KEGGGlycerolipid metabolism    PPAR signaling pathway   
NDEx NetworkGK
Atlas of Cancer Signalling NetworkGK
Wikipedia pathwaysGK
Orthology - Evolution
OrthoDB2710
GeneTree (enSembl)ENSG00000198814
Phylogenetic Trees/Animal Genes : TreeFamGK
HOVERGENP32189
HOGENOMP32189
Homologs : HomoloGeneGK
Homology/Alignments : Family Browser (UCSC)GK
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGK [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GK
dbVarGK
ClinVarGK
1000_GenomesGK 
Exome Variant ServerGK
ExAC (Exome Aggregation Consortium)GK (select the gene name)
Genetic variants : HAPMAP2710
Genomic Variants (DGV)GK [DGVbeta]
DECIPHERGK [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGK 
Mutations
ICGC Data PortalGK 
TCGA Data PortalGK 
Broad Tumor PortalGK
OASIS PortalGK [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGK  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGK
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)Leiden Muscular Dystrophy pages
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch GK
DgiDB (Drug Gene Interaction Database)GK
DoCM (Curated mutations)GK (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GK (select a term)
intoGenGK
Cancer3DGK(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM300474    307030   
Orphanet20608    20606    20607   
MedgenGK
Genetic Testing Registry GK
NextProtP32189 [Medical]
TSGene2710
GENETestsGK
Target ValidationGK
Huge Navigator GK [HugePedia]
snp3D : Map Gene to Disease2710
BioCentury BCIQGK
ClinGenGK
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2710
Chemical/Pharm GKB GenePA28700
Clinical trialGK
Miscellaneous
canSAR (ICR)GK (select the gene name)
Probes
Litterature
PubMed29 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGK
EVEXGK
GoPubMedGK
iHOPGK
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 15:50:41 CEST 2017

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