GKN1 (gastrokine 1)

2003-06-01  

Identity

HGNC
LOCATION
2p13.3
LOCUSID
ALIAS
AMP18,BRICD1,CA11,FOV,foveolin
FUSION GENES

Other Information

Locus ID:

NCBI: 56287
MIM: 606402
HGNC: 23217
Ensembl: ENSG00000169605

Variants:

dbSNP: 56287
ClinVar: 56287
TCGA: ENSG00000169605
COSMIC: GKN1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000169605ENST00000377938Q9NS71
ENSG00000169605ENST00000377938Q53YU7

Expression (GTEx)

0
500
1000
1500
2000

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
185939952008Decreased expression of gastrokine 1 and the trefoil factor interacting protein TFIZ1/GKN2 in gastric cancer: influence of tumor histology and relationship to prognosis.31
159618822005AMP-18 protects barrier function of colonic epithelial cells: role of tight junction proteins.28
238463372013GKN1-miR-185-DNMT1 axis suppresses gastric carcinogenesis through regulation of epigenetic alteration and cell cycle.21
218980902011Gastrokine 1 functions as a tumor suppressor by inhibition of epithelial-mesenchymal transition in gastric cancers.20
217929142011Overexpression of gastrokine 1 in gastric cancer cells induces Fas-mediated apoptosis.19
252396412014Gastrokine 1 inhibits the carcinogenic potentials of Helicobacter pylori CagA.14
170927862007Gastrokine 1 expression in patients with and without Helicobacter pylori infection.13
189274982008Molecular expression of Gastrokine 1 in normal mucosa and in Helicobacter pylori-related preneoplastic and neoplastic gastric lesions.12
217513842011Proteomics characterization of gastrokine 1-induced growth inhibition of gastric cancer cells.11

Citation

Dessen P

GKN1 (gastrokine 1)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/40717/gkn1